TP53 and Breast Cancer - Full text - MIT Libraries
I Liss - HUMAN MUTATION, 2003 - doi.wiley.com
p53 REVIEW ARTICLE TP53 and Breast Cancer ... The role of TP53 mutation as a prognostic
marker is reviewed as well as its role as a predictor for therapy response. ...
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human lung adenocarcinomas - Full text - MIT Libraries
M Shiraishi, A Sekiguchi, AJ Oates, MJ Terry, Y … - Oncogene, 2002 - nature.com
... region of the CDKN1A gene, which is a target of the TP53 gene product ... It has been
demonstrated that methylation of the CpG island of the HOXA5 gene results in ...
Cited by 7 - Web Search - nature.com - ncbi.nlm.nih.gov

Identification and classification of p53-regulated genes - Full text - MIT Libraries
J Yu, L Zhang, PM Hwang, C Rago, KW Kinzler, B … - Cancer Res, 2004 - dx.doi.org
... Home page H. Chen, S. Chung, and S. Sukumar HOXA5-Induced Apoptosis in ... NS Pellegata
Gene expression profiling of isogenic cells with different TP53 gene dosage ...
Cited by 199 - Web Search - pnas.org - pubmedcentral.nih.gov - milkpa.idv.tw - all 8 versions »

The p 53 pathway in breast cancer - Full text - MIT Libraries
M Gasco, S Shami, T Crook - Breast Cancer Res, 2002 - dx.doi.org
... A, Montesano R, Hall J: Abnormal expression of the ATM and TP53 genes in ... D, Evron
E, Odenwald WF, Jaffee E, Marks J, Sukumar S: Compromised HOXA5 function can ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - breast-cancer-research.com - citebase.eprints.org - all 10 versions »

Genomics of Pancreatic Cancer: Does It Make Any Improvement in Diagnosis, Prognosis and Therapy?
L KOPPER, A ZALATNAI, J TIMAR - PATHOLOGY ONCOLOGY RESEARCH, 2005 - webio.hu
... regulated, among them GATA4, GATA5, GATA6, gas- trin, villin1, villin2, HOXA5, SOX2
or ... errors were the following: ERBB2, EGFR1, K-ras, INK4A, TP53, SMAD4/DPC4. ...
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HOMOZYGOUS DELETIONS SCANNING IN TUMOR CELL LINES DETECTS PREVIOUSLY UNSUSPECTED LOCI - Full text - MIT Libraries
PCR Genomic - Int. J. Cancer, 2003 - doi.wiley.com
... 30%) affect only TP53 and RB, whereas for ovarian cancer, TP53 and KRAS ... For HOXA5
(7p12), primer sequences detecting indicated STS were found in UniGene (http ...
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Overexpression of mdm 2 and p 53 and association with progesterone receptor expression in benign … - Full text - MIT Libraries
A Das, WL Tan, J Teo, DR Smith - Neuropathology, 2002 - blackwell-synergy.com
... In this scenario, inappropriate activation of HOXA5 could lead to an upregulation
of both ... Detection of Tp53 gene mutation in human meningiomas: a study using ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Technical Advance
CM Chen, HL Chen, HCH Timothy, HAH Andrew, H Shi, … - American Journal of Pathology, 2003 - ajp.amjpathol.org
... FHIT NM 002012 3 4 1 1 1 0 2 3 HOXA5* NM 019102 12 21 6 9 4 4 7 13 ... GJB2
NM 004004 0 2 0 2 0 1 0 1 TP53 NM 000546 0 0 5 2 5 5 4 5 ...
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Genes, chromatin, and breast cancer: an epigenetic tale
LM Mielnicki, HL Asch, BB Asch - J Mammary Gland Biol Neoplasia, 2001 - kluweronline.com
... Genes affected by epigenetic changes in breast cancers include HoxA5, p21 WAF ,
gelsolin, BRCA1, BRCA2, E-cadherin, steroid hormone receptors, and retinoic ...
Cited by 10 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
YP Mosse, J Greshock, A Margolin, T Naylor, K Cole … - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
... was determined by Q-PCR with primer/probe pairs to MPO (17q23) referenced to TP53
(17p13) as ... HOX gene cluster includes HOXA1, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7 ...
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Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced …
A Barbouti, B Johansson, M Hoeglund, N Mauritzson, … - Genes Chromosomes and Cancer, 2002 - doi.wiley.com
... associated genes, such as CDKN2A, MYC, RAS, RB1, and TP53 (Johansson et al ... AC004080)
and containing the HOXA4, HOXA5, HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 ...
Cited by 6 - Web Search - lu-research.lub.lu.se - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Breast cancer gene discovery
K Polyak - Expert Reviews in Molecular Medicine, 2002 - journals.cambridge.org
... Germline mutations in several other genes (Table 1), including TP53 (‘tumour protein
p53’), PTEN (‘phosphatase and tensin homologue’), LKB1, CHK2 ...
Cited by 1 - Web Search - expertreviews.org - www-ermm.cbcu.cam.ac.uk - dx.doi.org - all 7 versions »

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity - Full text - MIT Libraries
N Genetics - Nature Genetics, 2002 - nature.com
... Whereas TP53 is inactivated by mutation in approximately half of all human tumors,
p53 function is widely believed to be abrogated in most, if not all, tumors ...
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Targeting STAT3 affects melanoma on multiple fronts
M Kortylewski, R Jove, H Yu - Cancer and Metastasis Reviews, 2005 - springerlink.com
... regression, increasing endogenous p53 expression by either overexpressing HOXA5
[83] or ... Low incidence of TP53 mutations in 10% of familial human melanomas is ...
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Comparison of genomic abnormalities betweenBRCAX and sporadic breast cancers studied by comparative … - Full text - MIT Libraries
J Gronwald, A Jauch, C Cybulski, B Schoell, B … - International Journal of Cancer, 2005 - doi.wiley.com
... 4,5 The involvement of genes predisposing for other family syndromes that show
moderately increased breast cancer risk such as PTEN, ATM, TP53, CHEK2 do not ...
Web Search - ncbi.nlm.nih.gov

Relevance of Breast Cancer Cell Lines as Models for Breast Tumours: An Update - Full text - MIT Libraries
M Lacroix, G Leclercq - Breast Cancer Research and Treatment, 2004 - springerlink.com
... HCC1937 BCC also have an acquired mutation of TP53 with wild-allele loss,
and an acquired homozygous deletion of the PTEN gene. ...
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Studies of p53 Tumor Suppression Activity in Mouse Models
D Martin-Zanca - Current Genomics, 2002 - ingentaconnect.com
... p53 is regulated at the transcriptional level, by NF-kB and HOXA5 [20], as well
as at the level of translation; however, p53 is controlled mainly at the level ...
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Untersuchungen zu funktionellen Wechselwirkungen des Kernproteins SAF-A
F Herrmann - ub.uni-konstanz.de
... Auf Transkriptionsebene wird die Expression von p53 durch die Transkriptionsfaktoren
NF-κB und HOXA5 (Webster et al., 1999; Raman et al., 2000) aktiviert. ...
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Die prognostische Relevanz der Zellzyklusregulationsproteine P21, P27 und P53 sowie der Apoptoserate …
ET Becker - tumb1.biblio.tu-muenchen.de
Page 1. Hals-Nasen-Ohrenklinik und Poliklinik Technische Universität München
Klinikum rechts der Isar (Direktor: Univ.-Prof. Dr. W. Arnold) ...
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POSTER SESSION I
CD Baldus, SM Tanner, A Ruppert, SP Whitman, G … - springerlink.com
... on the following chromosome arms: 2p (n=2, hMSH2), 5q (n=9, APC), 7q (n=5, D5486,
c-met), 8q (n=8, Eto), 11q (n=6, MLL), 17q (n=6, BRCA1), 17p (n=3, TP53). ...
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