TP 53 and MYC gene alterations independently predict poor prognosis in breast cancer patients
EMJJ Berns, JGM Klijn, M Smid, IL van Staveren, MP … - Genes Chromosomes and Cancer, 1996 - ncbi.nlm.nih.gov
TP53 and MYC gene alterations independently predict poor prognosis in breast
cancer patients. Berns EM, Klijn JG, Smid M, van Staveren ...
Cited by 29 - Web Search - Get it from MIT Libraries

Alterations of the TP53 gene in human gliomas
BK Rasheed, RE McLendon, JE Herndon, HS Friedman, … - Cancer Res, 1994 - intl-cancerres.aacrjournals.org
... TP53 protein to determine whether the incidence and type of TP53 alterations differ ...
and for amplification of the epidermal growth factor receptor, C-MYC, N-MYC ...
Cited by 87 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell … - Full text - MIT Libraries
R Supino, P Perego, L Gatti, C Caserini, C … - Eur J Cancer, 2001 - ingentaconnect.com
... A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant
small-cell lung cancer cell line. Authors: Supino R.; Perego ...
Cited by 8 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Frequent inactivation of CDKN2A and rare mutation of TP53 in PCNSL - Full text - MIT Libraries
JM Cobbers, M Wolter, J Reifenberger, GU Ring, F … - Brain Pathol, 1998 - ncbi.nlm.nih.gov
... one T-cell lymphoma) were investigated for genetic alterations and/or expression
of the genes BCL2, CCND1, CDK4, CDKN1A, CDKN2A, MDM2, MYC, RB1, REL, and TP53. ...
Cited by 25 - Web Search - ncbi.nlm.nih.gov

… between radiosensitivity and TP53 status, G1 arrest or protein levels of p53, myc, ras or raf in … - Full text - MIT Libraries
T Danielsen, B Smith-Sorensen, HA Gronlund, M … - Int J Radiat Biol, 1994 - dx.doi.org
... 75 , no. 9 , 1149 ± 1160 No association between radiosensitivity and TP53 status,
G 1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines ...
Cited by 6 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov

Molecular genetics of sporadic and familial breast cancer
KA Jones, MA Brown, E Solomon - Cancer Surv, 1995 - ncbi.nlm.nih.gov
... of cell regulation, from cell surface molecules responding to external signals
(eg ERBB2) to nuclear factors controlling gene transcription (eg TP53, MYC). ...
Cited by 14 - Web Search - Get it from MIT Libraries

No association between c-myc amplification and TP53 mutation in sarcoma tumorigenesis
JS Castresana, C Barrios, L Gomez, A Kreicbergs - Cancer Genet Cytogenet, 1994 - ncbi.nlm.nih.gov
... We found eight tumors with c-myc amplification and five different tumors with TP53
mutations but no tumors harbor both c-myc and TP53 alterations. ...
Cited by 4 - Web Search - Get it from MIT Libraries

Multiple Genomic Alterations Including N-myc Amplification in a Primary Large Cell Medulloblastoma - Full text - MIT Libraries
P Neurosurgery - Pediatric Neurosurgery, 2000 - content.karger.com
... Mass., USA) genomic DNA. Full-lenght cDNA N-myc, c-myc and TP53 probes
(kindly provided by Drs. Garrett Brodeur, Linda Harris and ...
Cited by 15 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions »

Prognostic implications of chromosome 17p deletions in human medulloblastomas
SK Batra, RE McLendon, JS Koo, S Castelino-Prabhu, … - J Neurooncol, 1995 - ncbi.nlm.nih.gov
... derived from medulloblastoma biopsies was analyzed to determine if deletions of
the 17p region, mutations of the TP53 gene, or amplification of the c-myc, N-myc ...
Cited by 46 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

c-MYC, RB-1, TP53, and Centromere 8 and 17 Copy Number in B-Cell Non-Hodgkin’s Lymphomas Assessed …
E Galteland, H Holte, T Stokke - Cytometry (Communications in Clinical Cytometry), 1999 - doi.wiley.com
... (25). Dual-color FISH was used to examine numerical alter- ations in c-MYC,
TP53, RB-1 and centromere 8 and 17 in this study of NHL. ...
Cited by 4 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

P 21 WAF 1, P 27 KIP 1, TP 53 and C-MYC analysis in 204 ovarian carcinomas treated with platinum- …
J Plisiecka-Halasa, G Karpinska, T Szymanska, I … - Annals of Oncology, 2003 - ncbi.nlm.nih.gov
Click here to read P21WAF1, P27KIP1, TP53 and C-MYC analysis in 204 ovarian
carcinomas treated with platinum-based regimens. Plisiecka ...
Cited by 4 - Web Search - Get it from MIT Libraries

Abnormal expression of pan-ras, c-myc and tp53 in squamous cell carcinoma of cervix: correlation … - Full text - MIT Libraries
HY Ngan, AN Cheung, SS Liu, DK Cheng, TY Ng, LC … - Oncol Rep, 2001 - ncbi.nlm.nih.gov
Abnormal expression of pan-ras, c-myc and tp53 in squamous cell carcinoma
of cervix: correlation with HPV and prognosis. Ngan HY ...
Cited by 3 - Web Search

Genetic characterization of HHV-8/KSHV-positive primary effusion lymphoma reveals frequent mutations …
G Gaidano, D Capello, AM Cilia, A Gloghini, T … - Genes Chromosomes Cancer, 1999 - doi.wiley.com
... Analysis of Other Genetic Lesions Gross rearrangements of BCL-1, BCL-2, BCL6, and
MYC, as well as mutations of the TP53 and MYC first exon–first intron border ...
Cited by 28 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Loss of heterozygosity at the TP53 gene: independent occurrence from genetic instability events in … - Full text - MIT Libraries
S Lizard-Nacol, JM Riedinger, G Lizard, AL Glasser … - Int J Cancer, 1997 - doi.wiley.com
... TABLE II – RELATIONSHIP BETWEEN ABSENCE OF LOH AT TP53 AND GENETIC ALTERATIONS IN
THE N 2 BREAST TUMORS ANALYZED TP53 N D17S30 cH-ras-1 c-myc c-erbB-2/neu ...
Cited by 6 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Determination of c-myc amplification and overexpression in breast cancer patients: evaluation of its … - Full text - MIT Libraries
A Scorilas, T Trangas, J Yotis, C Pateras, M … - British Journal of Cancer, 1999 - nature.com
... Determination of c-myc amplification and ... The values obtained for c-myc and
c-erbB-2 by densitometer scanning were normalized to values obtained for β-actin. ...
Cited by 29 - Web Search - dx.doi.org - nature.com - ncbi.nlm.nih.gov

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells - Full text - MIT Libraries
Z Li, S Van Calcar, C Qu, WK Cavenee, MQ Zhang, B … - Proceedings of the National Academy of Sciences, 2003 - pnas.org
... RBBP2, RFX5, RNF4, RXRB, SAP18, SAP30, SCML2, SP4, SUPT5H, TIF1, TMF1, TP53, TRAP150,
TRIP13 ... Many of the genes we identified as c-Myc Max targets play key roles ...
Cited by 46 - Web Search - panomics.com - zlab.bu.edu - rulai.cshl.org - all 10 versions »

5'Region and Exon 7 Mutations of the TP53 Gene in Two Cases of B-Cell Prolymphocytic Leukemia- … - Full text - MIT Libraries
C De Angeli, A Cuneo, G Aguiari, MG Roberti, N … - Cancer Genetics and Cytogenetics, 1998 - ingentaconnect.com
... was investigated by Southern blot and PCR-SSCP analysis, and TP53 expression was
investigated by Northern blot analysis and immunocytochemistry. C-MYC and BCL-1 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

HIGH PREVALENCE OF CODON 213 ARG8STOP MUTATIONS OF THE TP53 GENE IN HUMAN OVARIAN CANCER IN THE …
JGM Klijn, JA Foekens, EMJJ Berns - Cancer, 1998 - doi.wiley.com
... V AN P UTTEN , WLJ and F OEKENS , JA, TP53 and MYC gene alterations
independently predict poor prognosis in breast cancer patients. ...
Cited by 6 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Frequent Inactivation of CDKN2A and Rare Mutation of TP53 in PCNSL - Full text - MIT Libraries
C CDKN1A, MYC MDM, REL RB - Brain Pathology, 1998 - brainpathology.com
... T-cell lym- phoma) were investigated for genetic alterations and/or expression of
the genes BCL2, CCND1, CDK4, CDKN1A, CDKN2A, MDM2, MYC, RB1, REL, and TP53. ...
Web Search - brainpath.medsch.ucla.edu

… B-cell lymphoma with t (2; 8)(p12; q24) abnormality and absence of C-MYC amplification and TP53 … - Full text - MIT Libraries
A Potti, A Panwalkar, MC Ingebretson, SA Tharapel, … - Cancer Genetics and Cytogenetics, 2003 - ingentaconnect.com
... An indolent B-cell lymphoma with t(2;8)(p12;q24) abnormality and absence
of C-MYC amplification and TP53 deletion. A new variant? ...
Web Search - ncbi.nlm.nih.gov

[CITATION] P21 WAF1, P27 KIP1, TP53 and C-MYC analysis in 204 ovarian carcinomas treated with...
S In, PST Access, S Up
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Original Paper
A Chudecka-Glaz, K Urbanski, M Klimek, J Zielinski … - Annals of Oncology, 2003 - ingentaconnect.com
... Original Paper P21 WAF1 , P27 KIP1 , TP53 and C-MYC analysis in 204 ovarian
carcinomas treated with platinum-based regimens. Authors ...
Web Search - ingentaconnect.com

HT-29, a frequently used cell line, has the on-cogenetic alterations typical of colorectal cancer, …
C Corzo, M Petzold, X Mayol, B Espinet, M Salido, … - GENES, CHROMOSOMES & CANCER, 2003 - doi.wiley.com
RxFISH Karyotype and MYC Amplification in the HT-29 Colon Adenocarcinoma Cell Line ...
alterations typical of colorectal cancer, that is, APC and TP53 loss of ...
Web Search

Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell … - Full text - MIT Libraries
CDK CDK, MYC ETV - BLOOD, 2002 - bloodjournal.org
... The maximally selected 2 statistics tests yielded cut-off values for the genes BCL2,
CCND1, CDK4, TP53, CDKN1B, MYC, SELL, and ETV5, indicat- ing significant ...
Web Search

No correlation of c-myc overexpression and p53 mutations in liposarcomas - Full text - MIT Libraries
C Hoang-Vu, A Roessner - Virchows Arch, 1998 - springerlink.com
... Cancer Res 52:1107–1113 5. Berns EM, Klijn JG, Smid M, van Staveren IL, Look MP,
van Putten WL, Foekens JA (1996) TP53 and Myc gene alterations independently ...
Web Search

c-MYC and nodular malignant melanoma
KM Greulich, J Utikal, RU Peter, G Kraehn - Cancer, 2000 - doi.wiley.com
... TP53 and myc gene alterations inde- pendently predict poor prognosis in breast
cancer patients. Gene Chromosomes Cancer 1996;16:170–9. 23. ...
Cited by 4 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

c-myc, p53 AND bcl-2, APOPTOSIS-RELATED GENES IN INFILTRATING BREAST CARCINOMAS: EVIDENCE OF A LINK …
MG Le, MC Mathieu, S Douc-Rasy, ML Le Bihan, HA El … - Int. J. Cancer (Pred. Oncol.), 1999 - doi.wiley.com
c-myc, p53 AND bcl-2, APOPTOSIS-RELATED GENES IN INFILTRATING BREAST CARCINOMAS:
EVIDENCE OF A LINK BETWEEN bcl-2 PROTEIN OVER-EXPRESSION AND A LOWER RISK OF ...
Cited by 10 - Web Search - doi.wiley.com

Evidence for Distinct Pathomechanisms in Genetic Subgroups of Chronic Lymphocytic Leukemia Revealed … - Full text - MIT Libraries
DL Kienle, C Korz, B Hosch, A Benner, D Mertens, A … - Journal of Clinical Oncology, 2005 - jco.org
... Control Experiments Experiments were repeated for TP53, MYC, CDK4, BCL2, CCND3,
E2F1, and for all three housekeeping genes to obtain an independent data set. ...
Web Search - dx.doi.org - jco.org - ncbi.nlm.nih.gov

Oligo GEArray® Human Breast Cancer Biomarkers Microarray
PP Markers - search.cosmobio.co.jp
... Cell cycle: Cell cycle arrest/checkpoint: MYC, RB1, TP53. Negative regulation of
cell cycle: ATM, BAX, BRCA1, EGFR, ESR1, NME1, PTEN, RB1, TP53. ...
View as HTML - Web Search

Proto-oncogenes and p53 protein expression in normal cervical stratified squamous epithelium and … - Full text - MIT Libraries
HYS Ngan, SS Liu, H Yu, KL Liu, ANY Cheung - Eur J Cancer, 1999 - ingentaconnect.com
... oncogenes (epidermal growth factor receptor (EGFR), c-fms, c-myc, c-kit,
c-erbB-2 and pan-ras) and one tumour suppressor gene (TP53), by immunohistochemical ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Amplification of IGH/MYC Fusion in Clinically Aggressive IGH/BCL2-Positive Germinal Center B-Cell …
JI Martıno, MD Odero, R Hernandez, JC Cigudosa, X … - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
... Complicons affecting Igh/Myc have been reported previously in lymphomas of mouse
models simultaneously deficient in Tp53 and in genes of the nonhomologous end ...
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Identification of tumour-associated and germ line p 53 mutations in canine mammary cancer - Full text - MIT Libraries
N Veldhoen, J Watterson, M Brash, J Milner - British Journal of Cancer, 1999 - nature.com
... Nucleic Acids Res 18: 4961 Berns EM, Klijn JG, Smid M, van Staveren IL, Look MP,
van Putten WL and Foekens JA (1996) TP53 and MYC gene alterations ...
Cited by 6 - Web Search - nature.com - ncbi.nlm.nih.gov

Mutational analysis of transgenic mouse B cell lymphomas: indication of a Trp53-independent pathway …
SA Samant, RD Sheppard - Leukemia Research, 1999 - ingentaconnect.com
... full text options. Abstract: Deregulated myc, bcl-2 and/or TP53 gene expression
is associated with non-Hodgkin's B cell lymphomas (B-NHLs). ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

MYCL1, FHIT, SPARC, p16 (INK4) and TP53 genes associated to lung cancer in idiopathic pulmonary … - Full text - MIT Libraries
K Demopoulos, DA Arvanitis, DA Vassilakis, NM … - J. Cell. Mol. Med, 2002 - jcmm.ro
... in microsatellite DNA markers located in MYCL1, FHIT, SPARC, p16 Ink4 and TP53 genes
at ... Hatton KS, Tesfaye A., Yancopoulos GD, Alt FW, The human myc gene family ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a … - Full text - MIT Libraries
O Vafa, M Wade, S Kern, M Beeche, TK Pandita, GM … - Mol. Cell, 2002 - uiowa.edu
... c-Myc Can Induce DNA Damage, Increase Reactive Oxygen Species, and Mitigate p53
Function: A ... such as c-myc (Zindy et al., 1998) and ras (Serrano et al., 1997). ...
Cited by 64 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Analysis of genetic alterations related to the development and progression of breast carcinoma
K Nagayama, M Watanabi - Jpn J Cancer Res, 1993 - ncbi.nlm.nih.gov
... Non-US Gov't. Gene Symbols: ERBB2; HRAS; INT2; MYC; NME1; TP53. Substances:
DNA, Neoplasm; Proto-Oncogene Proteins; proto-oncogene protein ...
Cited by 4 - Web Search - Get it from MIT Libraries

Clinical relevance of genomic aberrations in homogeneously treated high-risk stage II/III breast … - Full text - MIT Libraries
A Seute, HP Sinn, RF Schlenk, R Emig, D Wallwiener … - International Journal of Cancer, 2001 - doi.wiley.com
... WL, et al. TP53 and MYC gene alterations independently predict poor prognosis
in breast cancer patients. Genes Chrom Cancer 1996 ...
Cited by 6 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Higher-grade transformation of follicular lymphoma− a continuous enigma
IS Lossos - Leukemia, 2005 - nature.com
... Molecular alterations affecting apoptosis (TP53 gene mutations, c-myc repression),
cell cycle control (inactivation of CDKN2A and CDKN2B genes) and ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

C-myc oncogene amplification in ductal carcinoma in situ of the breast - Full text - MIT Libraries
S Aulmann, M Bentz, HP Sinn - Breast Cancer Res Treat, 2002 - springerlink.com
... J Steroid Biochem Mol Biol 43: 13–19, 1992 5. Berns EMJJ, Klijn JG, Smid M, Staveren
ILV, Look MP, Putten WLV, Foekens JA: TP53 and MYC gene alterations ...
Cited by 3 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Novel regions of amplification on 8 q distinct from the MYC locus and frequently altered in oral …
C Garnis, BP Coe, A Ishkanian, L Zhang, MP Rosin, … - Genes Chromosomes and Cancer, 2004 - doi.wiley.com
... raise the possibility of additional oncogenes on 8q near the MYC locus that ... alter-
ation at 17p13 corresponds to the tumor suppressor gene TP53, whereas the ...
Cited by 13 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mutation analysis of CDP, TP53, and KRAS in uterine leiomyomas. - Full text - MIT Libraries
MI Patrikis, EJ Bryan, NA Thomas, GE Rice, MA … - Mol Carcinog, 2003 - doi.wiley.com
... over- expression is rare in ovarian carcinoma irrespective of TP53 mutation status ...
human cut homeodomain protein represses transcription from the c-myc promoter ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Oligo GEArray® Human Neurotrophin and Receptors Microarray
S Conditions - search.cosmobio.co.jp
... Cell cycle: BAX, BCL2, F2, FGF2, FGF9, IL1B, MYC, NF1, PTN, STAT1, TGFA,
TGFB1, TP53. Cell proliferation: BCL2, CCKBR, ETS1, FGF2 ...
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GENETIC CHANGES ASSOCIATED WITH TELOMERASE ACTIVITY IN BREAST CANCER
RL Loveday, J Greenman, PJ Drew, JRT Monson, MJ … - Int. J. Cancer (Pred. Oncol.), 1999 - doi.wiley.com
... P UTTEN , WL and F OEKENS , JA, TP53 and MYC gene alterations independently
predict poor prognosis in breast cancer patients. Genes ...
Cited by 16 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype - Full text - MIT Libraries
CV Ngo, M Gee, N Akhtar, D Yu, O Volpert, R … - Cell Growth Differ, 2000 - cgd.aacrjournals.org
... E., Loke SL, Pluznik DH, Watt R., Neckers LM A c-myc antisense oligodeoxynucleotide ...
N. Tumour suppressor genes and angiogenesis: the role of TP53 in fibroblasts ...
Cited by 31 - Web Search - phl.vet.upenn.edu - mail.vet.upenn.edu - ncbi.nlm.nih.gov - all 5 versions »

… aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute … - Full text - MIT Libraries
E Hilgenfeld, H Padilla-Nash, N McNeil, T Knutsen, … - British Journal of Haematology, 2001 - blackwell-synergy.com
... the aberrations detected led to loss of 17p and, therefore, loss of TP53 at 17p13 ...
Whereas most cases have shown an amplification of MYC in the dmin, three cases ...
Cited by 17 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

THE TP53 GENOTYPE BUT NOT IMMUNOHISTOCHEMICAL RESULT IS PREDICTIVE OF RESPONSE TO CISPLATIN-BASED …
D Kandioler-Eckersberger, S Kappel, M Mittlboeck, … - Cardiovascular Surgery - akh-wien.ac.at
... Al- though c-myc mutations are rarely seen in NSCLC, other cell cycle–affecting
proteins ... genes appear to be, at least in part, under the con- trol of TP53. ...
Cited by 13 - View as HTML - Web Search - jtcs.ctsnetjournals.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Oligo GEArray® Human Prostate Cancer Biomarkers Microarray
B APOC, C CHGA, C CLU, EGF COL6A1, ERK ERBB, FGF … - search.cosmobio.co.jp
... TP53. Cell cycle arrest: CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C,
CDKN3, INHA, MAPK12, MYC, RASSF1, TP53. Negative regulation ...
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Association between restriction fragment length polymorphism of the L-myc gene and susceptibility to … - Full text - MIT Libraries
L Background, L Conclusion - British Journal of Surgery, 1998 - doi.wiley.com
... Trump Band Harris C. Determination of the allelic frequencies of an L-myc and a ...
Prognostic value of TP53 and K-ras-2 mutational analysis in stage III carcinoma ...
Cited by 11 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov

Oligo GEArray® Rat Toxicology & Drug Resistance Microarray
S Conditions - search.cosmobio.co.jp
... Other growth/proliferation genes: Abl1, Brca1, Cdk4, Cdkn1a, Cdkn1b, Fos,
Igfbp6, Mdm2, Mt3, Myc, Nfkbia, Nfkbib, Ppard, Tp53. Drug ...
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The promyelocytic leukemia zinc finger protein down-regulates apoptosis and expression of the … - Full text - MIT Libraries
A Parrado, M Robledo, MR Moya-Quiles, LA Marin, C … - Proc Natl Acad Sci US A, 2004 - pubmedcentral.nih.gov
... CASP2, CASP3, CASP6, CASP7, CASP8, and CASP9), programmed cell death (PDCD1, PDCD2,
PDCD5, PDCD6, and PDCD8), transcription factors (TP53, MYC, PML, BCL6, STAT6 ...
Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov - all 6 versions »