Methylation of CpG dinucleotides and/or CCWGG motifs at the promoter of TP53 correlates with … - Full text - MIT Libraries
S REPORT - Oncogene, 2003 - nature.com
... Except for one sample in which no TP53 expression could be detected, the rest of
the samples analysed showed some degree of residual expression. ...
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Molecular alterations of the RB1, TP53, and MDM2 genes in primary and xenografted human …
A Pellin, J Boix-Ferrero, D Carpio, D Lopez- … - Diagn Mol Pathol, 1997 - molecularpathology.com
... high in cases 1, 7, 13, and 16 (>75% of tumor cells were positive) and low or absent
in the rest of the tumors. Two samples with TP53 mutation, osteosarcoma ...
Cited by 10 - Web Search - molecularpathology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients - Full text - MIT Libraries
J Alsner, M Yilmaz, P Guldberg, LL Hansen, J … - Clin Cancer Res, 2000 - clincancerres.aacrjournals.org
... Among the rest of the missense mutations within the structural/conserved domains,
a ... of the patients), they appear to define a novel class of TP53 mutations in ...
Cited by 15 - Web Search - biomedcentral.com - dx.doi.org - breast-cancer-research.com - all 12 versions »

ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse … - Full text - MIT Libraries
K Gronbaek, J Worm, E Ralfkiaer, V Ahrenkiel, P … - Blood, 2002 - bloodjournal.org
Page 1. NEOPLASIA ATM mutations are associated with inactivation of the
ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma ...
Cited by 17 - Web Search - auh.dk - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »

Association of p53 accumulation with TP53 mutations, loss of heterozygosity at 17p13, and DNA ploidy …
OP Clausen, RA Lothe, AL Borresen-Dale, P De … - Diagn Mol Pathol, 1998 - molecularpathology.com
... tumors were analyzed for point mutations within exons 5-8 of the TP53 gene using ...
antibody CMI was negligible, the former was chosen to stain the rest of the ...
Cited by 13 - Web Search - molecularpathology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated … - Full text - MIT Libraries
M Pallis, M Grundy, J Turzanski, R Kofler, N … - Blood, 2001 - bloodjournal.org
... stably transfected 4G5 subclone expresses a mutant conformation of TP53 at 37 ... For
analysis, cryopreserved samples were thawed and allowed to rest in CM enriched ...
Cited by 10 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Frequent somatic mutations in PTEN and TP 53 are mutually exclusive in the stroma of breast … - Full text - MIT Libraries
K Kurose, K Gilley, S Matsumoto, PH Watson, XP … - Nature Genetics, 2002 - nature.com
... Consistent with previous somatic mutational spectra for TP53 in various solid tumors,
four mutations were truncating and the rest were missense, with hot spots ...
Cited by 32 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Simultaneous Mutations in K-ras and TP53 Are Indicative of Poor Prognosis in Sporadic Colorectal …
JJ Gonzalez-Aguilera, S Oliart, MM Azcoita, AM … - American Journal of Clinical Oncology, 2004 - amjclinicaloncology.com
... However, LOH in TP53 was independent of the gender and the age of the patient ... mutations
was aspartic in 17 cases (63%) and nonaspartic in the rest (10 patients ...
Cited by 1 - Web Search - amjclinicaloncology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping - Full text - MIT Libraries
CA Telmer, J An, DE Malehorn, X Zeng, SM Gollin, … - Hum Mutat, 2003 - doi.wiley.com
... 19), and a combination of wild type and mutant signatures in the rest (two of ... The
tumor sample may have been entirely wild type (with the TP53 mutations in the ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Nachweis von TP53-Mutationen mittels Exfoliativzytologie (brush biopsy) oraler Leukoplakien - Full text - MIT Libraries
C Scheifele, H Schlechte, G Bethke, PA Reichart - Mund Kiefer GesichtsChir, 2002 - springerlink.com
... TP53-Mutationen Nein Ja ... Für Leukoplakien:L 1 <2 cm,L 2 2–4 cm, L 3 >4 cm,S 2 Mundboden
oder Zunge,S 1 rest- liche Mundhöhle,C 2 inhomogen,C 1 homogen ...
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Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and … - Full text - MIT Libraries
JL Soto, CM Cabrera, S Serrano, MA Lopez-Nevot - BMC Cancer, 2005 - biomedcentral.com
... in Table 1. Of the 39 tumors studied, 14 were primary (36%) while the rest were
metastatic (18 ... Mutation analysis of TP53, CDKN1A, CDKN2A, and CDKN2B genes. ...
Cached - Web Search - dx.doi.org - pubmedcentral.nih.gov - citebase.eprints.org - all 6 versions »

Methylation of CpG dinucleotides and/or CCWGG motifs at the promoter of TP 53 correlates with … - Full text - MIT Libraries
X Agirre, JL Vizmanos, MJ Calasanz, M Garcia- … - Oncogene, 2003 - nature.com
... Except for one sample in which no TP53 expression could be detected, the rest of
the samples analysed showed some degree of residual expression. ...
Cited by 9 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Increased genetic damage in oral leukoplakia from high risk sites
L Zhang, KJ Cheung, WL Lam, X Cheng, C Poh, R … - Cancer, 2001 - doi.wiley.com
... SCC. 17,19 Finally, two more markers formed the rest of the analysis: TP53,
located within the p53 gene, and CHRNB1 at 17p11.1-p12. ...
Cited by 5 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Free presentations - Full text - MIT Libraries
B JH, M Morgan, S Whawell, PA Atkin, PM Speight, … - J Oral Pathol Med - ingentaconnect.com
... LFS is frequently (∂70%) associated with germ- line TP53 mutations; the genetic
alteration in the rest of LFS cases remains un- identified. ...
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DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino, 17-demethoxygeldanamycin, an … - Full text - MIT Libraries
LR Kelland, SY Sharp, PM Rogers, TG Myers, P … - Journal of the National Cancer Institute, 1999 - jncicancerspectrum.oupjournals.org
... impor- tant oncogenic proteins, including Raf-1 and mutant p53 (also known as TP53). ...
cell growth inhibition assay in culture and by the ar- rest of xenograft ...
Cited by 67 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Caffeine-inhibitable control of the radiation-induced G2 arrest in L5178Y-S cells deficient in non- … - Full text - MIT Libraries
D Kowalczyk, P Janik - Radiat Environ Biophys, 2001 - springerlink.com
... that AT cells retain the Atr gene and Atr also is implied in the pathway leading
to G2 ar- rest and is inhibited by caffeine. Atr also modifies Tp53, so that ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Chromosome 17 loss-of-heterozygosity studies in benign and malignant tumors in neurofibromatosis …
SA Rasmussen, J Overman, SAM Thomson, SD Colman, … - Genes Chromosomes and Cancer, 2000 - doi.wiley.com
... The TP53 markers are on 17p13.1, and the rest of the markers are on 17q:
D17S841–D17S1800 lie in 17q11.2; D17S57, D17S73, and D17S250 lie at 17q12. ...
Cited by 30 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

DIFFERENT GENETIC PATHWAYS TO PROXIMAL AND DISTAL COLORECTAL CANCER INFLUENCED BY SEX-RELATED …
J Breivik, RA Lothe, GI Meling, TO Rognum, AL … - Cancer, 1997 - doi.wiley.com
... MIN exhibited a K-ras mutation, and only 2 of 14 (14%) had a TP53 mutation. ... between
samples from patients with a family history of cancer and the rest of the ...
Cited by 56 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

associated with action. Note also that the activation is mostly lateralized to the right hemisphere … - Full text - MIT Libraries
JCA Tomogr - Neuropsychologia, 1999 - dceg2.cancer.gov
... period and included the first brain volume of the following rest period. ... familial
cancer phenotype usually associated with inherited mutations in the TP53 gene ...
View as HTML - Web Search - dceg.cancer.gov

Relationship between abnormal p 53 protein and failure to express p 21 protein in human breast … - Full text - MIT Libraries
IK Bukholm, JM Nesland, R Karesen, U Jacobsen, AL … - The Journal of Pathology, 1997 - doi.wiley.com
... The rest of the lanes show tumours with wild-type sequence. ... Table II—Relationship
between p53 protein accumulation and TP53 gene mutation in 212 breast ...
Cited by 39 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Low rate of TP 53 germline mutations in breast cancer/sarcoma families not fulfilling classical … - Full text - MIT Libraries
DGR Evans, JM Birch, M Thorneycroft, G McGown, F … - Journal of Medical Genetics, 2002 - dx.doi.org
... basis of family history and many of the rest could have arisen de novo. 12 While
breast cancer is common in LFS and the penetrance of TP53 germline mutations ...
Cited by 4 - Web Search - jmg.bmjjournals.com - jmg.bmjjournals.com - ncbi.nlm.nih.gov

p 21 WAF 1/CIP 1 expression in primary lung adenocarcinomas: heterogeneous expression in tumor … - Full text - MIT Libraries
Y Takeshima, M Yamasaki, T Nishisaka, S Kitaguchi, … - Carcinogenesis, 1998 - carcin.oupjournals.org
... the center of the tumor was designated as ‘central region’, and the rest of the ... of
loss of heterozygosity (LOH) analysis of the p53 gene The TP53 locus was ...
Cited by 11 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Intronic deletion affecting a negative regulatory region of TP73 is related to breast and colorectal …
C Pena, JM Garcia, G Dominguez, J Silva, V Garcia, … - GENES, CHROMOSOMES & CANCER, 2004 - doi.wiley.com
... The im- munohistochemistry of TP53 was analyzed with the cl 1801 mouse monoclonal ...
The frequency of the rest of the haplotypes was more homogeneous (Table 2 ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Full Text View - Full text - MIT Libraries
KINA TRTKOVA, JII PLACHÝ - In Vitro Cellular & Developmental Biology-Animal - bioone.org
... tumor cell line PR9692. Both deletions destroy the DNA-binding domain and
perfectly match the rest of TP53 cDNA (Fig. 2 ). We have ...
Web Search

Chromosome analyses of 16 cases of Wilms tumor: different pattern in unfavorable histology - Full text - MIT Libraries
EM Peres, S Savasan, B Cushing, S Abella, AN … - Cancer Genet Cytogenet, 2004 - ingentaconnect.com
... exhibited an unfavorable histology (ie, anaplastic changes); the rest fell into ...
unfavorable histology had abnormalities of 17p, resulting in TP53 gene deletion ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Nephroblastoma arising in a germ cell tumor of testicular origin
RE Emerson, TM Ulbright, S Zhang, RS Foster, JN … - Am J Surg Pathol, 2004 - ajsp.com
... LOH of the TP53 tumor suppressor gene was observed in both metastases but not ... but
this tumor may have arisen from an intrascrotal mesonephric rest.38 Primary ...
Cited by 4 - Web Search - ajsp.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecularly Targeted Therapy in Acute Myeloid Leukemia - Full text - MIT Libraries
P BERNASCONI, M BONI, PM CAVIGLIANO, S CALATRONI, … - Ann. NY Acad. Sci, 2004 - annalsnyas.org
... them, nicotinamide, inhibits TP53-dependent apoptosis by antagonizing TP53
deacetylation mediated ... seven consecutive days followed by seven days of rest for ...
Web Search - annalsnyas.org - ncbi.nlm.nih.gov

Cushing Syndrome and Addison Disease
C Syndrome - content.karger.com
... chromo- somal region was the area around the 17p TP53 locus [54 ... middle and lower
panels) show furtherincreaseinthesignalintensityascom- pared to the rest of the ...
Web Search - content.karger.com

Three different subsite classification systems for carcinomas in the proximity of the GEJ, but is it … - Full text - MIT Libraries
K DOLAN, AI MORRIS, JR GOSNEY, JK FIELD, R SUTTON - Journal of Gastroenterology and Hepatology, 2004 - blackwell-synergy.com
... 37,38 It would seem that adenocarcinomas of the esophagus, GEJ and cardia have similar
TP53 mutations which are different to those detected in the rest of the ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Gene Therapy of Brain and Endocrine Tumors - Full text - MIT Libraries
G Palu, R Bonaguro, E Gnatta, E Franchin, L Barzon - Croat Med J, 2001 - cmj.hr
... tissue, in an anatomical compartment well sepa- rated from the rest of the body ... Tumor
Suppressor Gene Replacement Mutations of the TP53 tumor suppressor gene oc ...
View as HTML - Web Search - ncbi.nlm.nih.gov - cmj.hr

Detection of Microsatellite Alterations in Bronchial Washings in Squamous Cell Lung Cancer: the … - Full text - MIT Libraries
P Malhotra, D Behera, R Srinivasan, S Majumdar, A … - Japanese Journal of Clinical Oncology, 2004 - jjco.oupjournals.org
... Results: The sensitivities of the TP53 and D3S1300 loci in bronchial washings were ...
The rest of the tissue was deparaffinized and passed through graded alcohols ...
Web Search - jjco.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

A common polymorphism in XRCC 1 as a biomarker of susceptibility for chemically induced genetic …
Y Li, MJ Marion, A Rundle, PW Brandt-Rauf - Biomarkers, 2003 - dx.doi.org
... of VC-exposed workers characterized for the presence of biomarkers of TP53 mutations. ...
extraction for this study, but were otherwise similar to the rest of the ...
Cited by 8 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - epi-perspectives.com - all 7 versions »

Amplification of the Steroidogenic Factor 1 (SF-1) Gene in Childhood Adrenocortical Tumors
C Bonald, LR Cavalli, MAD Pianovski, E Lalli, R … - jcem.endojournals.org
... Southern Brazil, particularly in the state of Paraná, as compared to the rest of
the world (3.4-4.2 ... occurs in individuals with germline TP53 mutations (13). ...
Web Search - jcem.endojournals.org

Cell-cycle arrests and p 53 accumulation induced by geldanamycin in human ovarian tumour cells - Full text - MIT Libraries
AJ McIlwrath, VG Brunton, R Brown - Cancer Chemotherapy and Pharmacology, 1996 - springerlink.com
... Using dominant negative mutant TP53 transfectants of A2780 we have analysed the
possible ... important component of the pathway from DNA damage to ar- rest in the ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Biological characteristics of micrometastatic cancer cells in bone marrow
S Braun, K Pantel, UE Universitats-Frauenklinik, G … - Cancer Metastasis Rev, 1999 - kluweronline.com
... of disseminated tumor cells appeared to be non-cycling and rest in G 0 ... Table 2).
Counter to our expectations, coexpression of p53 protein (TP53) was only found ...
Cited by 17 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Multiplex detection of hotspot mutations by rolling circle-enabled universal microarrays - Full text - MIT Libraries
DP Ladner, JH Leamon, S Hamann, G Tarafa, T … - Lab Invest, 2001 - nature.com
... products contained the mutated primer sequence, whereas the rest of the ... 1, forward:
5'-GGCTGAATATAAACTTGTGG-3', reverse: 5'-AATGGTCCTGCACCAGTAAT-3'; TP53 exon 7 ...
Cited by 11 - View as HTML - Web Search - nature.com - ncbi.nlm.nih.gov

Amplification of the Steroidogenic Factor 1 Gene in Childhood Adrenocortical Tumors - Full text - MIT Libraries
BC Figueiredo, LR Cavalli, MAD Pianovski, E Lalli, … - The Journal of Clinical Endocrinology & Metabolism - jcem.endojournals.org
... Brazil, particularly in the state of Paraná, compared with the rest of the ... other
types of cancer, usually occur in individuals with germline TP53 mutations (14 ...
Web Search - jcem.endojournals.org - ncbi.nlm.nih.gov

Allelic deletions of cell growth regulators during progression of bladder cancer - Full text - MIT Libraries
H Primdahl, H von der Maase, M Christensen, H Wolf … - Cancer Res, 2000 - cancerres.aacrjournals.org
... progressing tumor group, and the presence of combined deletions of TP53 and RB1 ... visual
scoring by two independent and experienced observers on the rest of the ...
Cited by 12 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

p 53, p 21 and mdm 2 expression vs the response to radiotherapy in transitional cell carcinoma of … - Full text - MIT Libraries
R Rotterud, A Berner, R Holm, E Skovlund, SD Fossa - BJU International, 2001 - blackwell-synergy.com
... et al.[ 8] reported that the bladder cancer cell line expressing a TP53 mutation
was ... 4-5 weeks before radical cystectomy, which was undertaken after a rest of 4 ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

TP 53 mutations, amplification of P 63 and expression of cell cycle proteins in squamous cell … - Full text - MIT Libraries
P Taniere, G Martel-Planche, JC Saurin, C Lombard- … - British Journal of Cancer, 2001 - nature.com
... In the rest of the world, a variety of cultural and dietary habits have been ... Mutation
of the TP53 gene is the most frequent genetic alter- ation described to ...
Cited by 17 - Web Search - dx.doi.org - nature.com - ncbi.nlm.nih.gov

Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated … - Full text - MIT Libraries
K Kurose, XP Zhou, T Araki, SA Cannistra, ER Maher … - Am J Pathol, 2001 - ajp.amjpathol.org
... were PTEN immunostain-negative, 25 (51%) had reduced staining, and the rest (22%)
were ... 2/neu, KRAS, and C-MYC, somatic mutation of the TP53 tumor suppressor ...
Cited by 47 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov

Low frequency of TSG 101/CC 2 gene alterations in invasive human breast cancers - Full text - MIT Libraries
Q Wang, K Driouch, S Courtois, MH Champeme, I … - Oncogene, 1998 - nature.com
... We thus refer to TSG101 as TSG101/CC2 in the rest of this paper. ... For example, whereas
only 20 ± 25% of invasive breast adenocarcinomas display TP53 muta- tions ...
Cited by 8 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Assessing p53 status in breast cancer prognosis: where should you put the thermometer if you think … - Full text - MIT Libraries
RM Elledge - J. nat. Cancer Inst, 1996 - jncicancerspectrum.oupjournals.org
... the goal of defining the optimal method of assessing p53 (also known as TP53) status
for ... whether more DNA should be made or it is time to just stop and rest. ...
Cited by 19 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Dose-Dependent Transformation of Cells of Human Fibroblast Cell Strain MSU-1. I by Cobalt-60 Gamma …
S O’Reilly, M Walicka, SK Kohler, R Dunstan, VM … - RADIATION RESEARCH, 1998 - com.msu.edu
... in a portion of the tumor were returned to culture, and the rest of the ... Using
TP53-specific primers, the TP5.3’ coding sequence was amplified from the cDNA ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Search Article Keyword：
HG Ding, BD Gong, J Yu, J Gu, HY Zhang, ZB Shang, … - wjgnet.com
... RALBP1), splicing factor (45 kD) (SPF45), S-phase kinase-associated protein 2 (p45)
(SKP2), tumor protein p53 (Li-Fraumeni syndrome) (TP53) and topoisomerase ...
Cached - Web Search - wjgnet.com - wjgnet.com - wjgnet.com

Frequent gains on chromosome arms 1 q and/or 8 q in human endometrial cancer - Full text - MIT Libraries
A Suzuki, S Fukushige, S Nagase, N Ohuchi, S … - Human Genetics, 1997 - springerlink.com
... cancer (EC) is one of the most common fe- male pelvic malignant tumors in Japan
and the rest of the ... 1994), and inactivation of TP53 (10–20%) (Okamoto et al. ...
Cited by 14 - Web Search - ncbi.nlm.nih.gov

Characterization of a new cytogenetic subtype of ductal breast carcinomas - Full text - MIT Libraries
R Molist, Y Remvikos, B Dutrillaux, M Muleris - Oncogene, 2004 - nature.com
... It should be of interest to determine which genes, beside TP53, are associated with ...
When these two condi- tions were fulfilled, the rest of the stained nuclei ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Evaluation of the performance of a p53 sequencing microarray chip using 140 previously sequenced … - Full text - MIT Libraries
FP Wikman, ML Lu, T Thykjaer, SH Olesen, LD … - Clin Chem, 2000 - clinchem.org
... that can test the entire 1.2-kb coding sequence of the TP53 gene, including ... scores
and were therefore identical to the references, whereas the rest had scores ...
Cited by 42 - Web Search - intl.clinchem.org - clinchem.org - ncbi.nlm.nih.gov - all 5 versions »

Gain of 3 q and deletion of 11 q 22 are frequent aberrations in mantle cell lymphoma
O Monni, R Oinonen, E Elonen, K Franssila, L … - Genes Chromosomes and Cancer, 1998 - doi.wiley.com
... In addition, mutations of the TP53 tumor suppres- sor gene have recently been ...
Twenty-three specimens were obtained from lymph nodes, and the rest were obtained ...
Cited by 51 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

ATTACHMENT AND PROLIFERATION OF HUMAN OSTEOBLAST-LIKE CELLS ON COLLAGEN AND TRICALCIUM PHOSPHATE …
S AUREUS - Biotechnology - ptei.org
... Assessing TP53 status in human tumours to evaluate clinical outcome ... were imaged for
cell viability using red-green staining (ref.3), while the rest were plated ...
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