The endoplasmic reticulum stress response is stimulated through the continuous activation of … - Full text - MIT Libraries
J ichi Nozaki, H Kubota, H Yoshida, M Naitoh, J … - Genes to Cells, 2004 - genestocellsonline.org
... stress response is stimulated through the continuous activation of transcription
factors ATF6 and XBP1 in Ins2 +/Akita pancreatic ß cells. Jun ichi Nozaki 1 ,3 ...
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XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress. - Full text - MIT Libraries
S Kanemoto, S Kondo, M Ogata, T Murakami, F Urano, … - Biochem Biophys Res Commun, 2005 - ncbi.nlm.nih.gov
2005 Jun 17;331(4):1146-53. ... Click here to read XBP1 activates the transcription
of its target genes via an ACGT core sequence under ER stress. ...
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A possible association between the-116C/G single nucleotide polymorphism of the XBP1 gene and …
T Masui, R Hashimoto, I Kusumi, K Suzuki, T Tanaka … - Int J Neuropsychopharmacol, 2005 - ncbi.nlm.nih.gov
2005 Jun 1;:1-6 [Epub ahead of print], ... A possible association between the -116C/G
single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in ...
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About GATA3, HNF3A and XBP1, three genes co-expressed with the oestrogen receptor-a gene (ESR1) in …
M Lacroix, G Leclercq - Molecular and Cellular Endocrinology, 2004 - geocities.com
... 3 About GATA3, HNF3A, and XBP1, three genes co-expressed with the ... Three of them,
GATA3, HNF3A (also known as FOXA1), and XBP1 encode transcription factors. ...
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The unfolded protein response - Full text - MIT Libraries
CY Liu, RJ Kaufman - J. Cell Sci, 2003 - jcs.biologists.org
... ATF6 also induces XBP1 transcription, providing a positive feedback for the UPR. ...
Activated IRE1 recruits Jun N-terminal inhibitory kinase (JIK) and TRAF2 to ...
Cited by 16 - Web Search - ncbi.nlm.nih.gov

Signaling the Unfolded Protein Response from the Endoplasmic Reticulum - Full text - MIT Libraries
K Zhang, RJ Kaufman - J Biol Chem, 2004 - jbc.org
... of glycoproteins misfolded in the ER, depends solely on IRE1-XBP1 UPR signaling ... Under
the ER stress, activated IRE1 can bind c-Jun-N-terminal inhibitory kinase ...
Cited by 25 - Web Search - ncbi.nlm.nih.gov

Parkinsonian Mimetics Induce Aspects of Unfolded Protein Response in Death of Dopaminergic Neurons - Full text - MIT Libraries
WA Holtz, KL O'Malley - J Biol Chem, 2003 - jbc.org
... from MN9D cells treated with 6-OHDA and MPP + and used for reverse transcription
and semiquantitative RT-PCR using primer pairs to BiP/Grp78, c-Jun, and Xbp1. ...
Cited by 23 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Caspase-12 and ER-Stress-Mediated Apoptosis - Full text - MIT Libraries
EVA SZEGEZDI, UNA FITZGERALD, A SAMALI - Ann. NY Acad. Sci, 2003 - annalsnyas.org
... The resulting mRNA is translated into an XBP1 protein with an active ... 17,18 Alternatively,
Ire1 may activate proximal components of the c-jun N-terminal kinase ...
Cited by 8 - Web Search - annalsnyas.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Gene Expression Profiles of HeLa Cells Impacted by Hepatitis C Virus Non-structural Protein NS4B - Full text - MIT Libraries
Y Zheng, L Ye, J Liu, W Jing, KA Timani, X Yang, F … - Journal of Biochemistry and Molecular Biology, 2005 - jbmb.or.kr
... Yi Zheng, Lin-bai Ye*, Jing Liu, Wei Jing, Khalid A. Timani, Xiao-jun Yang, Fan
Yang, Wei Wang, Bo Gao and Zhen-hui Wu Key Laboratory of Virology, Ministry of ...
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Signaling the Unfolded Protein Response from the Endoplasmic Reticulum
TUPR Transducers, OM Regulator - aroianlab.ucsd.edu
... of glycoproteins misfolded in the ER, depends solely on IRE1- XBP1 UPR signaling
(42 ... Under the ER stress, activated IRE1 can bind c-Jun-N-terminal inhibitory ...
View as HTML - Web Search - cellbiology.wustl.edu - biochem.emory.edu - www-biology.ucsd.edu

Functional effects of a natural polymorphism in the transcriptional regulatory sequence of HLA-DQB1 - Full text - MIT Libraries
JS Beaty, KA West, GT Nepom - Mol Cell Biol, 1995 - mcb.asm.org
... element of DRA is known to interact with XBP1, XBP2 and c-Jun; at least one of these
factors (XBP2) acts cooperatively with RFX in order for binding to occur ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Salsolinol Causing Parkinsonism Activates Endoplasmic Reticulum-Stress Signaling Pathways in Human …
MKSSM Ebadi - Neurosignals, 2003 - content.karger.com
... 28, 29]. 6-OHDA, but not MPTP, significantly increased hallmarks of UPR
such as Bip, C-jun and processed Xbp1 mRNA. Both toxins ...
Cited by 2 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

ZF, C1, VCAF, CFF 11 NP_067035 127 77
J Bacteriol, J Virol, E Cell, AASM Journals - intl-mcb.asm.org
... CREBL1, 6, XP_004202.3, 320, 313. XBP1, TREB5, 22, NP_005071, 68, 126. Homo- and
heterodimer, C/EBP, ... CRE-BPa, 7, XP_004938.3, 366, 68. JUN, JUND, 19, NP_005345.2 ...
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The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in … - Full text - MIT Libraries
KT Chin, HJ Zhou, CM Wong, JMF Lee, CP Chan, BQ … - Nucleic Acids Research, 2005 - nar.oupjournals.org
... King-Tung Chin 1 , Hai-Jun Zhou 1 ,3 , Chun-Ming Wong 2 , Joyce Man-Fong Lee 2 ,
Ching-Ping Chan 1 , Bo-Qin Qiang 3 , Jian-Gang Yuan 3 , Irene Oi-lin Ng 2 and ...
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A trip to the ER: coping with stress - Full text - MIT Libraries
DT Rutkowski, RJ Kaufman - Trends Cell Biol, 2004 - biochem.wisc.edu
... regulation of the expression of many UPR-responsive genes shifts from ATF6 to XBP1. ...
activation of ASK1, a stress-activated MAP3K [36], and the c-jun N-terminal ...
Cited by 56 - View as HTML - Web Search - lbcm.iib.uba.ar - ncbi.nlm.nih.gov - all 4 versions »

Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... BRN2 TATA 257.1 HNF4 RORA1 80.4 CREB SRF 34.4 CHOP NF1 21.4 USF XBP1 256.3 EGR3
SP1 75.1 HNF1 TATA 33.9 HNF1 Oct-1 21.2 ... GATA-2 c-Jun GATA1_03 CREBP1CJUN_01 1.9 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Gene expression profile of murine long-term reconstituting vs. short-term reconstituting … - Full text - MIT Libraries
JF Zhong, Y Zhao, S Sutton, A Su, Y Zhan, L Zhu, C … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... with LTR HSC activity. These include Cited2, GATA3, Hdac3, Irf6, Jun B,
Nmyc1, Rnps1, Xbp1, and Zfp292. Little is known regarding ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Orchestrating the unfolded protein response in health and disease - Full text - MIT Libraries
RJ Kaufman - J. Clin. Invest, 2002 - dx.doi.org
... mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling ...
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. ...
Cited by 74 - Web Search - jci.org - pubmedcentral.nih.gov - biotech.korea.ac.kr - all 8 versions »

Identification of genes modulated in multiple myeloma using genetically identical twin samples - Full text - MIT Libraries
NC Munshi, T Hideshima, D Carrasco, M Shammas, D … - Blood, 2004 - bloodjournal.org
... RING1 AL031228 70.4 JUN J04111 66.6 PAK3 AF068864 54.3 FOSA V01512 38.1 ... ZNF91 L11672
67.6 EEF1A1 J04617 29.9 XBP1 Z93930 26.8 KRT8 X74929 17.9 ...
Cited by 13 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Regulation Of Major Histocompatibility Complex Class-Ii Genes: X, Y And Other Letters Of The … - Full text - MIT Libraries
C Benoist, D Mathis - Annual Review of Immunology, 1990 - immunol.annualreviews.org
Page 1. Annu. Rev. lmmunol. 1990. 8:681-715 Copyright © 1990 by Annual Reviews Inc.
All rights reserved REGULATION OF MAJOR HISTOCOMPATIBILITY COMPLEX ...
Cited by 165 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Mechanisms controlling early development of the liver - Full text - MIT Libraries
SA Duncan - Mech Dev, 2003 - genetics.wisc.edu
... Knockouts in several genes, including Hlx, c-Jun, Xbp1, and NF-kB, disrupt
growth and expansion of the hepatoblasts. Concurrent ...
Cited by 18 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

[CITATION] Survival and apoptosis signals in ER stress: the role of protein kinases
H Kadowaki, H Nishitoh, H Ichijo - Journal of Chemical Neuroanatomy, 2004
... XBP1 deletion also causes embryonic lethality (Masaki et al., 1999), consistent
with the notion that XBP1 acts down ... (2000b) reported that c-Jun amino-terminal ...
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Neuronal survival in the balance: are endoplasmic reticulum membrane proteins the fulcrum
GW Glazner, P Fernyhough - Cell Calcium, 2002 - sbrc.ca
Page 1. Cell Calcium (2002) 32(5–6), 421–433 0143-4160/02/$ – see front
matter © 2002 Elsevier Science Ltd. All rights reserved. ...
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Genes Regulated in Neurons Undergoing Transcription-dependent Apoptosis Belong to Signaling Pathways … - Full text - MIT Libraries
S Desagher, D Severac, A Lipkin, C Bernis, W … - J Biol Chem, 2005 - jbc.org
... 3; the Bcl-2 family members bim and DP5; the transcription factors c-jun, c-fos ...
activation of multiple genes mediated by transcription factors such as XBP1 (28 ...
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Building an antibody factory: a job for the unfolded protein response - Full text - MIT Libraries
JW Brewer, LM Hendershot - Nature Immunology, 2005 - nature.com
... is cleaved from the membrane and upregulates ER chaperone gene and Xbp1 transcription ...
of Ire1 results in recruitment of TRAF2, leading to Jun kinase activation ...
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Persistent eIF2α (P) is colocalized with cytoplasmic cytochrome c in vulnerable hippocampal neurons … - Full text - MIT Libraries
AB Page, CR Owen, R Kumar, JM Miller, JA Rafols, … - Acta Neuropathol, 2003 - springerlink.com
... Paschen’s group has prelimi- nary evidence of XBP1 processing consistent with ... known
as SAPKs (stress activated protein kinases) or JNKs (Jun N-terminal ...
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High-Throughput Immunoblotting Identifies Biotin-Dependent Signaling Proteins in HepG2 …
R Rodriguez-Melendez, JB Griffin, G Sarath, J … - nutrition.org
... We speculate that the increased nuclear abundance of both Fos/Jun and NF- B observed ...
Yoshida H., Matsui T., Yamamoto A., Okada T., Mori K. XBP1 mRNA is induced ...
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Repression of gene expression by oxidative stress - Full text - MIT Libraries
Y Morel, R Barouki - Biochem J, 1999 - bj.portlandpress.com
... the IL-2 gene promoter, whereas they activate the promoter of the c-jun gene [45 ...
It reported that oxidative stress induced transcription of the XBP1 protein, a ...
Cited by 103 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Oxidative stress responses of the yeast Saccharomyces cerevisiae - Full text - MIT Libraries
DJ Jamieson - Yeast, 1998 - doi.wiley.com
Page 1. YEAST Yeast 14, 1511–1527 (1998) Oxidative Stress Responses of the
Yeast Saccharomyces cerevisiae DEREK J. JAMIESON* Department ...
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Requirement of the p38 MAPK signaling pathway for the induction of Grp78/BiP by azetidine stress: … - Full text - MIT Libraries
S Luo, AS Lee - Biochem. J, 2002 - biochemj.org
... Published on 20 Jun 2002 as manuscript BJ20011802 ... activity [34]. Recently, it was
discovered that Ire1-p mediated splicing of XBP1 mRNA produces ...
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Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system
Y Qian, E Tiffany-Castiglioni - Neurochem. Res, 2003 - springerlink.com
... endoribonuclease activity of IRE1 to generate a C-terminus that converts XBP1 mRNA
into a ... signaling pathway of ER stress to the nucleus is c-Jun amino-terminal ...
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Search Article Keyword：
SO Lim, SG Park, JH Yoo, G Jung, YM Park, HJ Kim, … - wjgnet.com
... HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular
carcinomas and dysplastic nodules Seung Oe Lim, Sung Gyoo Park, Jun-Hi Yoo ...
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Complementary signaling pathways regulate the unfolded protein response and are required for C. … - Full text - MIT Libraries
X Shen, RE Ellis, K Lee, CY Liu, K Yang, A Solomon … - Cell, 2001 - bioc.rice.edu
... addition, the hsp-4 promoter contains a mammalian XBP1 (X box DNA binding protein)
binding site (Clauss ... scription factor Xbp1 (Yoshida et al., 2001b). ...
Cited by 90 - View as HTML - Web Search - biochem.northwestern.edu - faculty.buffalostate.edu - all 8 versions »

Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus- … - Full text - MIT Libraries
SO Lim, SG Park, JH Yoo, YM Park, HJ Kim, KT Jang, … - World J Gastroenterol, 2005 - wjgnet.com
... Seung Oe Lim, Sung Gyoo Park, Jun-Hi Yoo, Young Min Park, Hie-Joon Kim, Kee-Taek
Jang, Jae Won Cho, Byung Chul Yoo, Gu-Hung Jung, Cheol Keun Park ELSEVIER ...
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An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1 - Full text - MIT Libraries
D Oikawa, Y Kimata, M Takeuchi, K Kohno - Biochem J, 2005 - biochemj.org
... Cell Biol. 3, 158-164 13. Yoshida, H., Matsui, T., Yamamoto, A., Okada, T., and
Mori, K. (2001) XBP1 mRNA is ... Published on 15 Jun 2005 as manuscript BJ20050640 ...
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Classification of human B-ZIP proteins based on dimerization properties - Full text - MIT Libraries
C Vinson, M Myakishev, A Acharya, AA Mir, JR Moll, … - Mol. Cell. Biol, 2002 - dx.doi.org
... into eight previously identified families, (PAR, CREB, C/EBP, FOS, JUN, Maf, CNC ...
We also reassigned two sequences, XBP1 was moved from the FOS family to the ...
Cited by 47 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - tamza.com - all 8 versions »

Adult neuron survival strategies— slamming on the brakes - Full text - MIT Libraries
SC Benn, CJ Woolf - Nature Reviews Neuroscience, 2004 - nature.com
... 8. Whitfield, J., Neame, SJ, Paquet, L., Bernard, O. & Ham, J. Dominant-negative
c-Jun promotes neuronal survival by reducing BIM expression and inhibiting ...
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Combined Proteomics and Pathways Analysis of Collecting Duct Reveals a Protein Regulatory Network …
EJ Hoorn, JD Hoffert, MA Knepper - J Am Soc Nephrol, 2005 - jasn.asnjournals.org
... XBP1 X-box binding protein 1 IPA ... of five other proteins were increased (caspase 3,
p53, receptor for activated C kinase 1 [RACK1], c-src, and c-jun; Figure 7B ...
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Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted … - Full text - MIT Libraries
X Ma, T Husain, H Peng, S Lin, O Mironenko, N Maun … - Blood, 2002 - bloodjournal.org
... Jun Jun oncogene, part of AP1 transcriptional complex with Fos — — ... Xbp1
Essential for plasma cell differentiation, liver development ...
Cited by 6 - Web Search - info.med.yale.edu - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »

Identifying genetic networks underlying myometrial transition to labor - Full text - MIT Libraries
N Salomonis, N Cotte, A Zambon, K Pollard, K … - Genome Biology, 2005 - dx.doi.org
... prostaglandin receptor subtypes, estrogen, cortisol and transcription factors
c-Jun and c ... regulated Nfil3, and the X-box binding protein Xbp1, also upregulated ...
Web Search - microarrays.berkeley.edu - bmc.ub.uni-potsdam.de - gladstone.ucsf.edu - all 10 versions »

Neuroprotection and Neurorepair
R Table, O Institutions - Restorative Neurology and Neuroscience, 2002 - iospress.metapress.com
Page 1. Restorative Neurology and Neuroscience 20 (2002) 219–295 IOS Press
0922-6028/02/$8.00 © 2002 – IOS Press. All rights reserved 219 ...
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Endoplasmic reticulum signaling as a determinant of recombinant protein expression - Full text - MIT Libraries
RE Cudna, AJ Dickson - Biotechnology and Bioengineering, 2003 - doi.wiley.com
... then followed by IRE1-dependent excision of a small intron from the XBP1 mRNA (Fig ...
to caspase-12 activation, IRE1 signals through TRAF2 to JNK (c-Jun N-terminal ...
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Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic … - Full text - MIT Libraries
HF Frierson, AK El-Naggar, JB Welsh, LM Sapinoso, … - Am J Pathol, 2002 - ajp.amjpathol.org
... Henry F. Frierson, Jr.,* Adel K. El-Naggar, † John B. Welsh, ‡ Lisa M. Sapinoso, ‡
Andrew I. Su, § Jun Cheng, ¶ Takashi Saku, ¶ Christopher A. Moskaluk ...
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Role of Herp in the endoplasmic reticulum stress response - Full text - MIT Libraries
O Hori, F Ichinoda, A Yamaguchi, T Tamatani, M … - Genes to Cells, 2004 - genestocellsonline.org
... for 8 h and subjected to Western blotting with anti-KDEL, anti-XBP1, anti-CHOP ... as
control and JNK activity was measured based on the phosphorylation of c-jun. ...
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Identification of a family of cAMP response element-binding protein coactivators by genome-scale … - Full text - MIT Libraries
V Iourgenko, W Zhang, C Mickanin, I Daly, C Jiang, … - Proc. Natl. Acad. Sci. USA, 2003 - pnas.org
... including the JNK-inducing kinases MAP3K11 and MAP3K12, junD, and c-jun (data not ...
a number of CRE-binding proteins CREB1, CRE-BPa, and XBP1, potently activated ...
Cited by 21 - Web Search - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Genome wide analysis of common and specific stress responses in adult drosophila melanogaster - Full text - MIT Libraries
F Girardot, V Monnier, H Tricoire - BMC Genomics, 2004 - biomedcentral.com
... by the ROS or through signaling pathways, and have either pro- (Jun, p53) or anti ...
in our genetic experiments, halving the dosage of the Xbp1 gene resulted in ...
Cited by 2 - Cached - Web Search - dx.doi.org - pubmedcentral.nih.gov - citebase.eprints.org - all 6 versions »

The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the … - Full text - MIT Libraries
NN Iwakoshi, AH Lee, LH Glimcher - Immunological Reviews, 2003 - blackwell-synergy.com
... XBP-1 has been shown to form a stable heterodimer with the protein encoded by the
proto-oncogene c-fos but not with c-jun (8). The X2 sequence of HLA DRA and ...
Cited by 14 - Web Search - ncbi.nlm.nih.gov

Transmission of proteotoxicity across cellular compartments
T Yoneda, F Urano, D Ron - Signal Transduction, 2002 - dx.doi.org
... Signal transduction by the c-Jun N-terminal kinase ... IRE1-mediated unconventional mRNA
splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling ...
Cited by 4 - Web Search - genesdev.org - saturn.med.nyu.edu - ncbi.nlm.nih.gov - all 8 versions » - Get it from MIT Libraries

Insights Into Host Responses Against Pathogens from Transcriptional Profiling - Full text - MIT Libraries
RG Jenner, RA Young - Nature Reviews Microbiology, 2005 - nature.com
... their co-activator BCL3,the activa- tor protein-1 (AP1) components (JUN, JUNB and ...
BATF and CREM), as well as BCL6, CEBPG, EGR4, HIF1α,NFATC1, SMAD7 and XBP1. ...
Web Search - ncbi.nlm.nih.gov - csa.com

From the Cover Identification of a family of cAMP response element-binding protein coactivators by … - Full text - MIT Libraries
V Iourgenko, W Zhang, C Mickanin, I Daly, C Jiang, … - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... including the JNK-inducing kinases MAP3K11 and MAP3K12, junD, and c-jun (data not ...
a number of CRE-binding proteins CREB1, CRE-BPa, and XBP1, potently activated ...
Web Search