A competitive mechanism of CArG element regulation by YY1 and SRF: implications for assessment of …
KA Martin, A Gualberto, MF Kolman, J Lowry, K … - DNA Cell Biol, 1997 - ncbi.nlm.nih.gov
A competitive mechanism of CArG element regulation by YY1 and SRF: implications
for assessment of Phox1/MHox transcription factor interactions at CArG elements ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Functional antagonism between YY1 and the serum response factor - Full text - MIT Libraries
A Gualberto, D LePage, G Pons, SL Mader, K Park, … - Mol. Cell. Biol, 1992 - mcb.asm.org
... Unlike that of YY1, SRF overexpression alone did not influence the transcriptional
activity of the target sequence, but SRF overexpression could reverse YY1 ...
Cited by 75 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

YY1 facilitates the association of serum response factor with the c-fos serum response element - Full text - MIT Libraries
S Natesan, M Gilman - Mol. Cell. Biol, 1995 - mcb.asm.org
... This enhancement requires the binding of YY1 to SRE DNA. YY1 and SRF can cooccupy
the SRE at least transiently. ... YY1 and SRF can cooccupy the SRE. ...
Cited by 51 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Displacement of BrdUrd-Induced YY1 by Serum Response Factor Activates Skeletal {alpha}-Actin … - Full text - MIT Libraries
T Lee, Y Shi, RJ Schwartz - Proceedings of the National Academy of Sciences - pnas.org
... Since the functions of YY1 and SRF appear to be developmentally regulated, the
convergence of their binding sites upon the SRE constitutes an integrated ...
Cited by 40 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Influence of promoter potency on the transcriptional effects of YY 1, SRF and Msx-1 in transient … - Full text - MIT Libraries
T Lee, ME Bradley, JL Walowitz - Nucleic Acids Research, 1998 - nar.oupjournals.org
... References. Influence of promoter potency on the transcriptional effects of
YY1, SRF and Msx-1 in transient transfection analysis. Techung ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Context-dependent Transcriptional Regulation - Full text - MIT Libraries
CJ Fry, PJ Farnham - J Biol Chem, 1999 - dx.doi.org
... Overlapping binding sites for Sp1 and Egr, E2F and CDF-1 (CDE), and YY1
and SRF (SRE) can result in competitive binding. Therefore ...
Cited by 76 - Web Search - jbc.org - ncbi.nlm.nih.gov

Transforming growth factor-beta response elements of the skeletal alpha- actin gene. Combinatorial … - Full text - MIT Libraries
WR MacLellan, TC Lee, RJ Schwartz, MD Schneider - J Biol Chem, 1994 - jbc.org
... Mutations of SRE1 that prevent recognition by SRF and YY1, or SRF alone, virtually
abolish SkA transcription in both TGF beta- and vehicle-treated cells ...
Cited by 88 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal a-actin transcription …
TEC LEE, Y SHIt, RJ SCHWARTZ - Cell, 1992 - pnas.org
... Since the functions of YY1 and SRF appear to be developmentally regulated, the
convergence of their binding sites upon the SRE constitutes ...
Cited by 18 - Web Search - Get it from MIT Libraries

Competition between negative acting YY1 versus positive acting serum response factor and tinman … - Full text - MIT Libraries
CY Chen, RJ Schwartz - Mol Endocrinol, 1997 - mend.endojournals.org
... We proposed that the skeletal -actin promoter could be repressed or activated by
two functionally opposite SRE-binding proteins, YY1 and SRF, depending on the ...
Cited by 16 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

YY1 binds to and regulates cis-acting negative elements in the Epstein-Barr virus BZLF1 promoter - Full text - MIT Libraries
EA Montalvo, M Cottam, S Hill, YJ Wang - J. Virol, 1995 - jvi.asm.org
... serum-in- ducible and basal expression of the c-fos promoter; this repres- sion
is apparently due to the functional antagonism between YY1 and SRF (15, 22). ...
Cited by 20 - Web Search - pubmedcentral.nih.gov - intl-jvi.asm.org - ncbi.nlm.nih.gov - all 5 versions »

… myosin heavy chain gene expression at the transcriptional level-possible role of SRF and YY1 … - Full text - MIT Libraries
S Itoh, Y Katoh, H Konishi, N Takaya, T Kimura, M … - J Mol Cell Cardiol, 2001 - ingentaconnect.com
... Nitric Oxide Regulates Smooth-muscle-specific Myosin Heavy Chain Gene Expression
at the Transcriptional Level-Possible Role of SRF and YY1 Through CArG Element. ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov

Proteolytic Regulation of the Zinc Finger Transcription Factor YY 1, a Repressor of Muscle- … - Full text - MIT Libraries
JL Walowitz, ME Bradley, SJ Chen, TC Lee - J Biol Chem, 1998 - jbc.org
... PAGE. Proteins were electrotransferred to Immobilon-P membrane. The YY1 and SRF
antibodies were described previously (24). The chemiluminescence ...
Cited by 20 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Expression of the serum response factor gene is regulated by serum response factor binding sites. - Full text - MIT Libraries
JA Spencer, RP Misra - J Biol Chem, 1996 - jbc.org
... in CArG box complexes containing SRF. However, we are continuing to
investigate a possible role for YY1 in SRF promoter activity. ...
Cited by 37 - Web Search - jbc.org - ncbi.nlm.nih.gov

The Dystrophin Promoter Is Negatively Regulated by YY 1 in Undifferentiated Muscle Cells - Full text - MIT Libraries
F Galvagni, E Cartocci, S Oliviero - J Biol Chem, 1998 - jbc.org
... binding. Competitive binding between YY1 and SRF was described previously
for other muscle-specific CArG elements (35, 37, 38). ...
Cited by 17 - Web Search - unisi.it - unisi.it - ncbi.nlm.nih.gov - all 5 versions »

Two YY-1-binding Proximal Elements Regulate the Promoter Strength of the TATA-less Mouse … - Full text - MIT Libraries
E Johansson, K Hjortsberg, L Thelander - J Biol Chem, 1998 - jbc.org
... composed as described (11), and the antibodies against YY1, SRF, DP-2 (Santa Cruz
Biotechnology), NF-YA, and NF-YB (kindly provided by Dr. Roberto Mantovani ...
Cited by 15 - Web Search - medchem.umu.se - jbc.org - ncbi.nlm.nih.gov

The hardwiring of development: organization and function of genomic regulatory systems - Full text - MIT Libraries
MI Arnone, EH Davidson - Development, 1997 - dev.biologists.org
... 1858 MI Arnone and EH Davidson MEF2 HF1 TEF1 SP1 HD MDF SRF YY1 MAPF SRF MEF2 MDF
MDF MDF HD MDF MAPF MDF MDF MEF2 SRF HF1 SRF SRF SRF MDF SRF MDF SRF SRF YY1 ...
Cited by 258 - Web Search - ipef.br - wwwlib.bionet.nsc.ru - bioinformatics.buffalo.edu - all 8 versions »

YY 1 Is Regulated by O-Linked N-Acetylglucosaminylation(O-GlcNAcylation) - Full text - MIT Libraries
M Hiromura, CH Choi, NA Sabourin, H Jones, D … - J Biol Chem, 2003 - jbc.org
... with a double-stranded oligonucleotide corresponding to the CArG DNA box of the
smooth muscle -actin promoter, which contains a binding site for YY1 and SRF. ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Increased actin polymerization reduces the inhibition of serum response factor activity by Yin Yang … - Full text - MIT Libraries
PD Ellis, KM Martin, C Rickman, JC Metcalfe, PR … - Biochem J, 2002 - biochemj.org
... Mutation of the CArG box to inhibit YY1 or SRF binding indicated that both factors
were required for the LIM kinase response in VSMCs and C2C12 cells. ...
Cited by 7 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Serum response element associated transcription factors in mouse embryos: serum response factor, YY1 …
S Liu, B Peng, J Ma, Y Liu, S Ng - Dev. Genet, 1995 - ncbi.nlm.nih.gov
... SRF binds WGA-agarose and apparently is O-glycosylated. ... Furthermore, we showed that
the fastest migrating complex contains the Yin-Yang 1 (YY1) factor. ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, … - Full text - MIT Libraries
EE Furlong, T Rein, F Martin - Mol Cell Biol, 1996 - mcb.asm.org
... A number of such composite binding elements have been described, eg, YY1/MGF (39),
YY1/SRF (34), and YY1/NF- B binding sites (36). Hyde-De- Ruyscher et al. ...
Cited by 37 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Smooth muscle {alpha}-actin CArG elements coordinate formation of a smooth muscle cell-selective, … - Full text - MIT Libraries
CP Mack, MM Thompson, S Lawrenz-Smith, GK Owens - Circ Res, 2000 - circresaha.org
... 38 39 However, like SRF, YY1 is expressed in a wide range of tissues, and its
role in cell-type–specific regulation is unclear at this time. ...
Cited by 42 - Cached - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 8 versions »

Role of the Transcription Start Site Core Region and Transcription Factor YY1 in Rous Sarcoma Virus … - Full text - MIT Libraries
CM Mobley, L Sealy - J Virol, 1998 - jvi.asm.org
... Gal4 DBD). The two upper complexes, TSSC(A) and -(B), were not affected by
addition of YY1, SRF, or Gal4 DBD antibodies. In addition ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov - all 5 versions »

MyoD Distal Regulatory Region Contains an SRF Binding CArG Element Required for MyoD Expression in … - Full text - MIT Libraries
A L'honore, NJ Lamb, M Vandromme, P Turowski, G … - Mol. Biol. Cell, 2003 - molbiolcell.org
... complexes containing respectively the transcription factor YY1 and SRF associated
with the ... As shown in Figure 2B, complexes formed with SRF and YY1 ...
Cited by 3 - Web Search - molbiolcell.org - intl.molbiolcell.org - pubmedcentral.nih.gov - all 8 versions »

In Silico Genetics: Identification of a Functional Element Regulating H2-E {alpha} Gene Expression - Full text - MIT Libraries
G Liao, J Wang, J Guo, J Allard, J Cheng, A Ng, S … - Science, 2004 - sciencemag.org
... binding site. The CA..G allele–containing haplotype has the YY1 and SRF
binding sites and also had high H2-E gene expression. (B ...
Cited by 3 - Web Search - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Transcriptional regulation of smooth muscle contractile apparatus expression - Full text - MIT Libraries
J Solway, SM Forsythe, AJ Halayko, JE Vieira, MB … - Am. J. Respir. Crit. Care Med, 1998 - ajrccm.atsjournals.org
... A competitive mechanism of CArG element regulation by YY1 and SRF: implications
for assessment of Phox1/MHox transcription factor interactions at CArG elements ...
Cited by 13 - Web Search - ajrccm.atsjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Interaction of transcription factor YY 1 with a replication-enhancing element, REE 1, in an … - Full text - MIT Libraries
C Obuse, T Okazaki, H Masukata - Nucleic Acids Research, 1998 - nar.oupjournals.org
... The filled and open triangles below the SRE sequence show bases protected from
methylation by binding of YY1 and SRF respectively (37). ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Genomic organization and mapping of mouse CDV(carnitine deficiency-associated gene expressed in … - Full text - MIT Libraries
M Higashi, K Kobayashi, M Iijima, S Wakana, M … - Mammalian Genome, 2000 - springerlink.com
... 1997) through the relevant web sites and identified binding sites including TATA,
Nkx-2.5, Sp1, C/EBP, YY1, SRF, and CREB, as shown in Fig. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

SRF protein is upregulated during stretch-induced hypertrophy of rooster ALD muscle - Full text - MIT Libraries
M Flueck, JA Carson, RJ Schwartz, FW Booth - J Appl Physiol, 1999 - jap.org
... Transactivation of the skeletal -actin promoter through SRE1 occurs through
alterations in SRF and YY1 protein concentrations (21). ...
Cited by 19 - Cached - Web Search - jap.physiology.org - jap.org - ncbi.nlm.nih.gov - all 5 versions »

YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity - Full text - MIT Libraries
MJ O'Connor, SH Tan, CH Tan, HU Bernard - J. Virol, 1996 - jvi.asm.org
... YY1 Represses Human Papillomavirus Type 16 Transcription ... The role of YY1 as repressor,
activator, or initiator appears to be context dependent (33). ...
Cited by 52 - Web Search - intl-jvi.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Context-dependent Transcriptional Regulation
TACB Achieved - cbr.med.harvard.edu
... Normally, YY1 blocks access of SRF and prevents activation of the promoter. ... The SRE
in the c-fos promoter is also bound by both YY1 and SRF (19). ...
View as HTML - Web Search - genomecenter.ucdavis.edu - mcardle.oncology.wisc.edu - genomics.ucdavis.edu - all 6 versions »

Helicobacter-induced Intestinal Metaplasia in the Stomach Correlates with Elk-1 and Serum Response … - Full text - MIT Libraries
G Rieder, AJ Tessier, XT Qiao, B Madison, DL … - J Biol Chem, 2005 - jbc.org
... prepared after incubating the cells with the bacteria for 0, 3, and 24 h. In untreated
extracts, there was binding of YY1 and SRF and no binding of Elk-1 (Fig. ...
Web Search - jbc.org - ncbi.nlm.nih.gov

SRF and TEF-1 control of chicken skeletal a-actin gene during slow-muscle hypertrophy
JA CARSON, RJ SCHWARTZ, FW BOOTH - Am. J. Physiol, 1996 - ajpcell.physiology.org
Page 1. SRF and TEF-1 control of chicken skeletal ... Booth. SRF and TEF-1 control of
chicken skeletal cx-actin gene during slow-muscle hypertrophy. Am. J. Physiol. ...
Cited by 33 - Web Search - ajpcell.physiology.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Polycomb Ezh 2 methyltransferase regulates muscle gene expression and skeletal muscle … - Full text - MIT Libraries
G Caretti, M Di Padova, B Micales, GE Lyons, V … - Genes & Development, 2004 - genesdev.org
... (K) Immunoblot of extracts derived from myoblasts at different stages of
differentiation probed with antibodies against Ezh2, YY1, SRF, and Sp1. ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Multiple tandemly repeated binding sites for the YY1 repressor and transcription factors AP-1 and SP …
W Gu, Q Huang, GS Hayward - J. Biomed. Sci, 1995 - ncbi.nlm.nih.gov
... Several of the YY1 sites also bound weakly to SRF. The intron also contains four
clustered purine/pyrimidine tracts of between 16 and 23 bp long. ...
Cited by 2 - Web Search - Get it from MIT Libraries

The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex - Full text - MIT Libraries
M Hassler, TJ Richmond - The EMBO Journal, 2001 - embojournal.npgjournals.com
... serum response factor (SRF) (Norman et al., 1988), ternary complex factors (TCFs)
(Shaw et al., 1989) and YY1 (Natesan and Gilman, 1995). The SRF homodimer and ...
Cited by 34 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 6 versions »

Binding of SRF to CArG box sequences is necessary but not sufficient to restrict gene expression to … - Full text - MIT Libraries
M Strobeck, S Kim, JCL Zhang, C Clendenin, KL Du, … - J. Biol. Chem, 2004 - jbc.org
... required. Nuclear protein binding assays revealed that SME-4 binds SRF, YY1
and four additional SMC nuclear proteins. Taken together ...
Web Search

5'CArG degeneracy in smooth muscle {alpha}-actin is required for injury-induced gene suppression in … - Full text - MIT Libraries
JA Hendrix, BR Wamhoff, OG McDonald, S Sinha, T … - J. Clin. Invest, 2005 - jci.org
... Furthermore, studies show that binding sites for SRF and YY1 overlap one another
and that by inducing a single transversion point mutation at any one of a ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ijp-online.com - all 7 versions »

Molecular Medicine
SMACAGE Coordinate, RFCA Complex - circres.ahajournals.org
... 38,39 However, like SRF, YY1 is expressed in a wide range of tissues, and its role
in cell-type–specific regulation is unclear at this time. 40 ...
Web Search

Organization and myogenic restricted expression of the murine serum response factor gene - Full text - MIT Libraries
NS Belaguli, LA Schildmeyer, RJ Schwartz - J. Biol. Chem, 1997 - jbc.org
... modulated by YY1. Displacement of YY1 by increased SRF binding activity during
myogenesis may facilitate the SRF autoregulatory loop. ...
Cited by 61 - Web Search - jbc.org - ncbi.nlm.nih.gov

Analysis of linked human epsilon and gamma transgenes: effect of locus control region hypersensitive … - Full text - MIT Libraries
W Zhu, C TomHon, M Mason, T Campbell, E Shelden, N … - Blood, 1999 - bloodjournal.org
... Analysis of Linked Human and Transgenes: Effect of Locus Control Region Hypersensitive
Sites 2 and 3 or a Distal YY1 Mutation on Stage-Specific Expression ...
Cited by 2 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulation of SRF Activity by Rho Family GTPases
R TREISMAN, AS ALBERTS, E SAHAI - Cold Spring Harbor Symposia on Quantitative Biology, 1998 - dx.doi.org
... 1996), YY1 (Natesan and Gilman 1995), and C/EBP (Sealy et al ... We are currently seeking
to identify novel SRF interaction partners, by use of both modified yeast ...
Cited by 21 - Web Search - cshl-symposium.org - cshl-symposium.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Impaired repression at a vasopressin promoter polymorphism underlies overexpression of vasopressin … - Full text - MIT Libraries
C Murgatroyd, A Wigger, E Frank, N Singewald, M … - The Journal of Neuroscience, 2004 - jneurosci.org
... Martin KA, Gualberto A, Kolman MF, Lowry J, Walsh K (1997) A competitive mechanism
of CArG element regulation by YY1 and SRF: implications for assessment of ...
Cited by 2 - Web Search - dx.doi.org - jneurosci.org - ncbi.nlm.nih.gov

Neurobiology of Disease
C Murgatroyd, A Wigger, E Frank, N Singewald, M … - mpipsykl.mpg.de
... This cis-regulatory ele- ment, also known as a serum response element (SRE), is
bound byserumresponsefactor(SRF)(Treisman,1987),YY1(Martinet al., 1997), and CBF ...
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Transfection of Keratinocytes Abrogates Detectable DNA-Binding Activity of CCAAT Displacement …
J Narahari, A Roman - DNA and Cell Biology, 2002 - dx.doi.org
... Influence of promoter potency on the transcriptional effects of YY1, SRF and
Msx-1 in transient transfection analysis. Nucleic Acids Res. 26, 3215–3220. ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Decisions, Decisions... SRF Coactivators and Smooth Muscle Myogenesis - Full text - MIT Libraries
MW Majesky - Circ Res, 2003 - circres.ahajournals.org
... other SRF cofactors including MRTFs, Nkx, and paired-type homeodomain proteins,
GATA factors, HOP, Barx2B, chromatin-organizing factors HMGI(Y) and SSRP1, YY1, ...
Cited by 5 - Web Search - ahavj.ahajournals.org - intl-circres.ahajournals.org - ncbi.nlm.nih.gov

The YY1 Transcription Factor is a Component of Ribonucleoprotein Complexes in Xenopus laevis Oocytes …
S Saskatchewan, AD Ficzycz - library.usask.ca
... overlapping binding sites have been observed for YY1 and serum response factor Page
24. 11 (SRF, a 67 kDa phosphoprotein) on the c-fos serum response element ...
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A switch region determines the cell type-specific positive or negative action of YY1 on the activity … - Full text - MIT Libraries
T Bauknecht, F Jundt, I Herr, T Oehler, H Delius, … - J. Virol, 1995 - jvi.asm.org
... YY1 regu- lates expression of the human c-fos promoter by competition with serum
response factor SRF for binding to the serum response element (19), to CArG ...
Cited by 35 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Analysis of Linked Human and Transgenes: Effect of Locus Control Region Hypersensitive Sites 2 and 3 … - Full text - MIT Libraries
W Zhu, C TomHon, M Mason, T Campbell, E Shelden, N … - Blood, 1999 - bloodjournal.org
... Transgenes: Effect of Locus Control Region Hypersensitive Sites 2 and 3 or
a Distal YY1 Mutation on Stage-Specific Expression Patterns ...
Web Search

YY1 Represses Vitamin D Receptor-Mediated 25-Hydroxyvitamin D 3 24-Hydroxylase Transcription: Relief … - Full text - MIT Libraries
M Raval-Pandya, P Dhawan, F Barletta, S Christakos - Mol Endocrinol, 2001 - mend.endojournals.org
... addition, the YY1 site in the fos promoter (33) and in the -actin promoter (27)
overlaps the binding site for the serum response factor (SRF). YY1 sites also ...
Cited by 8 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional … - Full text - MIT Libraries
J Kalenik, D Chen, ME Bradley, SJ Chen, TC Lee - Nucleic Acids Research, 1997 - nar.oupjournals.org
... ( Bottom ) Western blots of YY1 and SRF. Proteins were isolated from skeletal
muscle cell cultures at 24, 48 and 72 h. In vitro ...
Cited by 31 - Web Search - nar.oupjournals.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »