1: Mol Cell Endocrinol. 2004 Apr 30;219(1-2):1-7. 

About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen
receptor-alpha gene (ESR1) in breast cancer.

Lacroix M, Leclercq G.

Laboratoire Jean-Claude Heuson de Cancerologie Mammaire, Institut Jules Bordet,
Universite Libre de Bruxelles, 127 Boulevard de Waterloo, B-1000 Bruxelles,
Belgium. marc.lacroix@ulb.ac.be

In breast tumours and breast cancer cell (BCC) lines, microarray analyses have
revealed that a series of genes are expressed in close association with the
oestrogen receptor-alpha (ER-alpha) gene, ESR1. Three of them, GATA3, HNF3A
(also known as FOXA1), and XBP1 encode transcription factors. Here, we present
these factors and we discuss their potential involvement in the
ER-alpha-mediated actions in BCC. We notably show the relations that exist, or
that might exist, between these factors and the oestrogen-inducible trefoil
factor TFF1. Copyright 2004 Elsevier Ltd.

PMID: 15149721 [PubMed - indexed for MEDLINE]


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