Summary of results |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Parameters |
|
|
|
threshold =
low FN |
|
maxd = 25, 50, 200 bp |
|
|
species = hs |
|
conserved
binding sites |
|
|
|
|
total n |
|
% of each pattern hs[1] |
|
% of each pattern mm[2] |
|
Chi2 test[3] |
expression p value[4] |
TSS position bias[5] |
order p value (binomial) |
maxd[6] |
|
name 1[7] |
name 2[8] |
hs |
mm |
5'-3' |
3'-5' |
3'-3' |
5'-5' |
5'-3' |
3'-5' |
3'-3' |
5'-5' |
p hs |
p mm |
hs |
mm |
hs |
mm |
hs |
mm |
hs |
mm |
|
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
15 |
16 |
17 |
18 |
19 |
20 |
21 |
22 |
|
CEBP |
SRY |
7971 |
9023 |
22% |
22% |
31% |
25% |
22% |
21% |
32% |
25% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CEBP |
LYF1 |
5499 |
5612 |
27% |
29% |
22% |
22% |
27% |
27% |
23% |
23% |
<1E-16 |
9.80E-08 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
CEBP |
PAX4 |
7728 |
7419 |
23% |
20% |
35% |
22% |
22% |
18% |
37% |
23% |
<1E-16 |
<1E-16 |
|
|
* |
|
|
|
25 50 200 |
25 |
|
FOXJ2 |
PBX1 |
6386 |
6158 |
29% |
28% |
22% |
21% |
30% |
29% |
20% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
FOXJ2 |
HFH3 |
4787 |
5708 |
16% |
16% |
34% |
34% |
14% |
13% |
38% |
35% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
FOXJ2 |
FOXD3 |
4907 |
5791 |
19% |
19% |
30% |
31% |
17% |
16% |
33% |
34% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
FOXJ2 |
SRY |
6687 |
8688 |
31% |
31% |
19% |
19% |
35% |
34% |
16% |
16% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
FOXJ2 |
PAX4 |
5029 |
5338 |
32% |
26% |
21% |
22% |
33% |
27% |
19% |
21% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
FOXJ2 |
GKLF |
3525 |
3883 |
32% |
28% |
21% |
20% |
34% |
27% |
19% |
20% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
CEBPB |
CEBPB |
12878 |
7604 |
23% |
23% |
27% |
27% |
23% |
23% |
28% |
27% |
<1E-16 |
1.90E-15 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CEBPB |
CEBP |
23494 |
7097 |
27% |
26% |
24% |
23% |
27% |
28% |
23% |
22% |
<1E-16 |
8.90E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CEBPB |
MZF1 |
7105 |
6800 |
29% |
28% |
22% |
22% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
** |
* |
|
|
25 50 200 |
25 |
|
CEBPB |
PAX4 |
6794 |
6547 |
24% |
22% |
32% |
21% |
24% |
21% |
31% |
24% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
CEBPB |
GKLF |
5734 |
5500 |
30% |
27% |
22% |
20% |
28% |
28% |
22% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CEBPB |
SP1 |
4336 |
4293 |
29% |
29% |
21% |
21% |
29% |
27% |
22% |
23% |
<1E-16 |
4.30E-13 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
TST1 |
MZF1 |
4997 |
5009 |
27% |
29% |
21% |
23% |
28% |
28% |
21% |
23% |
<1E-16 |
2.20E-13 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
TST1 |
GKLF |
4893 |
4549 |
28% |
30% |
21% |
22% |
27% |
29% |
22% |
22% |
<1E-16 |
7.30E-15 |
**** |
|
|
|
|
|
25 50 |
25 |
|
AP2 |
SP1 |
20606 |
14676 |
23% |
22% |
28% |
27% |
22% |
21% |
30% |
27% |
<1E-16 |
<1E-16 |
|
|
* |
|
|
|
25 50 |
25 |
|
AP2 |
GATA3 |
6954 |
6621 |
23% |
21% |
28% |
28% |
23% |
23% |
27% |
28% |
<1E-16 |
1.50E-12 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
RREB1 |
3480 |
2035 |
29% |
32% |
17% |
21% |
30% |
34% |
16% |
20% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
AP2 |
P300 |
10684 |
8135 |
23% |
22% |
29% |
26% |
22% |
22% |
29% |
26% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
MZF1 |
16840 |
11983 |
22% |
22% |
29% |
27% |
21% |
21% |
31% |
27% |
<1E-16 |
<1E-16 |
|
|
*** |
**** |
|
|
25 50 |
25 |
|
AP2 |
GATA1 |
13280 |
10660 |
24% |
22% |
28% |
26% |
24% |
22% |
29% |
25% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
LYF1 |
9883 |
7296 |
22% |
23% |
28% |
27% |
23% |
21% |
29% |
28% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
PAX4 |
3721 |
3501 |
20% |
38% |
18% |
24% |
20% |
39% |
17% |
24% |
<1E-16 |
<1E-16 |
**** |
|
** |
* |
|
|
25 50 200 |
25 |
|
AP2 |
GKLF |
7811 |
5825 |
22% |
21% |
29% |
29% |
21% |
21% |
29% |
29% |
<1E-16 |
<1E-16 |
|
|
* |
**** |
|
|
25 50 200 |
25 |
|
CDPCR1 |
TATA |
4963 |
5113 |
24% |
23% |
31% |
22% |
24% |
23% |
32% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
CDPCR1 |
CDPCR3HD |
5234 |
5942 |
29% |
29% |
21% |
21% |
29% |
29% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
HNF1 |
AML1 |
4290 |
4987 |
22% |
38% |
19% |
21% |
23% |
37% |
18% |
22% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 50 |
|
HNF1 |
SRY |
8026 |
8696 |
23% |
21% |
30% |
25% |
22% |
21% |
30% |
27% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
NFY |
SP1 |
10056 |
6115 |
24% |
22% |
28% |
26% |
24% |
22% |
29% |
25% |
<1E-16 |
3.40E-15 |
|
|
**** |
*** |
|
|
25 50 200 |
25 |
|
NFY |
MZF1 |
6548 |
6437 |
22% |
21% |
30% |
27% |
23% |
22% |
29% |
26% |
<1E-16 |
<1E-16 |
|
|
* |
* |
|
|
25 50 200 |
25 50 |
|
NFY |
PAX4 |
4439 |
4327 |
25% |
31% |
22% |
21% |
26% |
32% |
19% |
23% |
<1E-16 |
<1E-16 |
**** |
|
* |
|
|
|
25 50 200 |
25 |
|
LMO2COM |
SP1 |
4548 |
4991 |
29% |
29% |
20% |
22% |
28% |
29% |
22% |
21% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
LMO2COM |
GATA2 |
6343 |
8101 |
29% |
28% |
20% |
22% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
LMO2COM |
GATA3 |
6582 |
8459 |
30% |
30% |
20% |
20% |
29% |
30% |
21% |
20% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
LMO2COM |
MZF1 |
7021 |
7806 |
29% |
29% |
21% |
21% |
28% |
29% |
21% |
22% |
<1E-16 |
<1E-16 |
|
|
|
* |
|
|
25 50 200 |
25 |
|
LMO2COM |
PAX4 |
10035 |
6975 |
23% |
22% |
27% |
28% |
23% |
22% |
27% |
28% |
<1E-16 |
1.10E-16 |
|
|
|
* |
|
|
25 50 200 |
25 50 |
|
LMO2COM |
GKLF |
4864 |
5553 |
31% |
29% |
20% |
20% |
29% |
30% |
20% |
20% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
MEIS1 |
TGIF |
3873 |
5773 |
21% |
21% |
31% |
28% |
21% |
21% |
31% |
27% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
RFX1 |
GKLF |
4710 |
5062 |
27% |
29% |
21% |
23% |
27% |
29% |
23% |
21% |
<1E-16 |
<1E-16 |
**** |
|
* |
|
|
|
25 50 200 |
25 |
|
PAX6 |
SRY |
7673 |
8846 |
22% |
22% |
30% |
25% |
21% |
21% |
31% |
27% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
PAX6 |
PAX4 |
6356 |
6623 |
23% |
22% |
31% |
24% |
22% |
23% |
31% |
24% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
PAX6 |
GKLF |
5430 |
5971 |
23% |
20% |
30% |
26% |
22% |
21% |
30% |
27% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
TATA |
CDPCR3HD |
5157 |
5393 |
23% |
22% |
33% |
21% |
22% |
23% |
33% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
USF |
COUP |
2894 |
3686 |
23% |
21% |
34% |
23% |
23% |
21% |
35% |
21% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
USF |
MEIS1A/HOXA9 |
6840 |
9124 |
22% |
21% |
35% |
22% |
21% |
23% |
34% |
23% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
USF |
PAX4 |
3478 |
4298 |
21% |
32% |
20% |
27% |
20% |
32% |
20% |
29% |
<1E-16 |
<1E-16 |
**** |
|
**** |
* |
|
|
25 50 200 |
25 |
|
PBX1 |
NFAT |
7024 |
6455 |
27% |
28% |
22% |
23% |
28% |
27% |
22% |
23% |
<1E-16 |
6.70E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
PBX1 |
HFH3 |
5693 |
5760 |
20% |
22% |
30% |
28% |
20% |
18% |
33% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
PBX1 |
FOXD3 |
5638 |
5619 |
22% |
21% |
28% |
29% |
21% |
17% |
30% |
31% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
PBX1 |
SRY |
6622 |
7496 |
31% |
29% |
19% |
21% |
31% |
32% |
17% |
20% |
<1E-16 |
<1E-16 |
|
|
* |
|
|
|
25 50 200 |
25 |
|
PBX1 |
PAX4 |
5844 |
5661 |
37% |
23% |
19% |
21% |
39% |
24% |
18% |
20% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
PBX1 |
GKLF |
3834 |
3740 |
31% |
28% |
20% |
21% |
36% |
25% |
20% |
19% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
YY1 |
MZF1 |
6230 |
6857 |
20% |
20% |
31% |
28% |
21% |
20% |
31% |
28% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
YY1 |
PAX4 |
5381 |
6042 |
27% |
31% |
21% |
21% |
26% |
30% |
23% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
YY1 |
SP1 |
4082 |
4343 |
21% |
21% |
32% |
27% |
21% |
21% |
32% |
27% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
YY1 |
P300 |
7327 |
4950 |
23% |
22% |
29% |
26% |
23% |
21% |
28% |
28% |
<1E-16 |
2.00E-14 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
YY1 |
GKLF |
4333 |
5015 |
21% |
20% |
32% |
28% |
21% |
20% |
29% |
30% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
COUP |
TCF11 |
4179 |
5501 |
17% |
17% |
49% |
16% |
18% |
18% |
47% |
18% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
NFAT |
SP1 |
5769 |
5713 |
28% |
29% |
21% |
22% |
30% |
29% |
20% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
NFAT |
AREB6 |
7711 |
8509 |
22% |
22% |
27% |
28% |
22% |
23% |
27% |
28% |
<1E-16 |
<1E-16 |
|
|
* |
|
|
|
25 50 200 |
25 |
|
NFAT |
HNF4 |
8912 |
9682 |
29% |
27% |
22% |
22% |
29% |
27% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
NFAT |
FOXD3 |
5526 |
5573 |
22% |
22% |
27% |
29% |
21% |
21% |
29% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
NFAT |
GATA3 |
8170 |
8872 |
28% |
28% |
22% |
22% |
27% |
27% |
23% |
22% |
<1E-16 |
3.30E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
NFAT |
SRY |
7934 |
8660 |
30% |
27% |
21% |
21% |
30% |
28% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
NFAT |
ELK1 |
8350 |
8940 |
29% |
28% |
21% |
22% |
29% |
28% |
22% |
21% |
<1E-16 |
<1E-16 |
|
|
*** |
** |
|
|
25 50 200 |
25 |
|
NFAT |
P300 |
5645 |
6131 |
28% |
28% |
22% |
22% |
27% |
28% |
23% |
22% |
<1E-16 |
8.60E-13 |
|
|
* |
|
|
|
25 50 200 |
25 50 |
|
NFAT |
MZF1 |
8692 |
8621 |
29% |
30% |
20% |
20% |
29% |
30% |
20% |
21% |
<1E-16 |
<1E-16 |
|
|
* |
|
|
|
25 50 200 |
25 |
|
NFAT |
IK1 |
8128 |
8135 |
28% |
29% |
22% |
21% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
NFAT |
PAX4 |
7319 |
7049 |
36% |
22% |
19% |
23% |
37% |
23% |
18% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
NFAT |
GKLF |
6613 |
6549 |
32% |
31% |
19% |
18% |
32% |
31% |
19% |
18% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
SOX9 |
SOX5 |
6710 |
7663 |
31% |
31% |
19% |
19% |
31% |
31% |
19% |
19% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CEBP |
GKLF |
4688 |
4713 |
29% |
29% |
21% |
20% |
27% |
30% |
21% |
22% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
P53 |
TCF11 |
6546 |
8811 |
21% |
22% |
35% |
22% |
22% |
23% |
34% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
P53 |
MZF1 |
8461 |
8256 |
22% |
23% |
27% |
28% |
21% |
24% |
26% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
CREL |
RREB1 |
1828 |
1596 |
25% |
21% |
35% |
19% |
26% |
19% |
35% |
20% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
CREL |
GKLF |
6054 |
5996 |
20% |
26% |
25% |
29% |
20% |
26% |
25% |
29% |
<1E-16 |
<1E-16 |
|
|
|
** |
|
|
25 50 |
25 |
|
SP1 |
GATA2 |
5806 |
6080 |
29% |
28% |
21% |
22% |
29% |
28% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
SP1 |
AREB6 |
4296 |
3745 |
20% |
20% |
31% |
29% |
20% |
19% |
32% |
29% |
<1E-16 |
<1E-16 |
**** |
|
* |
* |
|
|
25 50 200 |
25 |
|
SP1 |
HNF4 |
9557 |
8860 |
29% |
28% |
21% |
22% |
30% |
27% |
21% |
22% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
GATA3 |
6105 |
6419 |
31% |
31% |
18% |
19% |
31% |
30% |
19% |
19% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
SP1 |
15471 |
11949 |
32% |
32% |
18% |
19% |
34% |
34% |
15% |
17% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
SP1 |
AML1 |
5667 |
5285 |
29% |
30% |
20% |
21% |
29% |
30% |
20% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
RREB1 |
2978 |
2151 |
15% |
16% |
36% |
33% |
12% |
12% |
42% |
34% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
ELK1 |
13601 |
11761 |
27% |
28% |
23% |
22% |
27% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
**** |
* |
|
|
25 50 200 |
25 |
|
SP1 |
P300 |
8937 |
7611 |
32% |
30% |
18% |
20% |
32% |
30% |
19% |
20% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
MZF1 |
14745 |
11825 |
32% |
32% |
18% |
19% |
34% |
33% |
16% |
17% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
CMYB |
8585 |
7841 |
28% |
28% |
23% |
21% |
27% |
28% |
24% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
SP1 |
GATA1 |
11018 |
9640 |
29% |
29% |
21% |
21% |
30% |
29% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
IK1 |
10185 |
8368 |
30% |
29% |
20% |
21% |
31% |
29% |
20% |
20% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
LYF1 |
8652 |
7287 |
30% |
33% |
19% |
19% |
30% |
33% |
18% |
18% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SP1 |
PAX4 |
2959 |
3218 |
23% |
22% |
22% |
33% |
20% |
22% |
23% |
35% |
<1E-16 |
<1E-16 |
**** |
|
**** |
** |
|
|
25 50 200 |
25 |
|
SP1 |
GKLF |
7203 |
6512 |
33% |
35% |
14% |
17% |
33% |
38% |
14% |
15% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
MEIS1A/HOXA9 |
AP4 |
7286 |
9270 |
23% |
24% |
30% |
22% |
23% |
24% |
30% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
TCF11 |
12105 |
15312 |
16% |
16% |
50% |
17% |
18% |
17% |
48% |
17% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MEIS1A/HOXA9 |
MSX1 |
7943 |
9642 |
23% |
30% |
24% |
23% |
23% |
30% |
23% |
24% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
NKX25 |
6391 |
7854 |
22% |
30% |
26% |
21% |
22% |
29% |
27% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
HSF1 |
CP2 |
7004 |
8232 |
24% |
30% |
23% |
24% |
24% |
28% |
23% |
24% |
<1E-16 |
3.80E-12 |
|
|
|
|
|
|
25 50 |
25 |
|
HSF1 |
GKLF |
5991 |
6535 |
25% |
32% |
19% |
24% |
26% |
32% |
20% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
AP4 |
PAX4 |
3766 |
4401 |
22% |
33% |
19% |
27% |
20% |
33% |
18% |
29% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
HFH3 |
FOXD3 |
4489 |
5686 |
32% |
32% |
18% |
18% |
35% |
36% |
15% |
14% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
HFH3 |
SRY |
6052 |
8768 |
18% |
18% |
32% |
33% |
13% |
14% |
36% |
36% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
HFH3 |
PAX4 |
4743 |
5245 |
19% |
20% |
37% |
24% |
17% |
20% |
40% |
24% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
HFH3 |
GKLF |
3107 |
3514 |
21% |
20% |
32% |
28% |
18% |
20% |
36% |
26% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
1-Oct |
1-Oct |
9485 |
8580 |
28% |
28% |
23% |
22% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
1-Oct |
SRY |
7792 |
8172 |
29% |
27% |
22% |
22% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
1-Oct |
PAX4 |
6469 |
6243 |
30% |
25% |
23% |
23% |
30% |
25% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
1-Oct |
GKLF |
4939 |
4870 |
29% |
29% |
20% |
21% |
31% |
28% |
20% |
21% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
GATA2 |
GATA3 |
7030 |
9136 |
29% |
30% |
20% |
21% |
28% |
29% |
22% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
GATA2 |
RREB1 |
1277 |
1315 |
21% |
18% |
35% |
26% |
19% |
22% |
34% |
25% |
<1E-16 |
1.80E-14 |
**** |
|
|
|
|
|
25 50 |
25 |
|
GATA2 |
MZF1 |
8222 |
8954 |
29% |
28% |
21% |
22% |
28% |
29% |
22% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
GATA2 |
PAX4 |
6934 |
8116 |
23% |
22% |
27% |
28% |
23% |
22% |
28% |
27% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
GATA2 |
GKLF |
5568 |
6429 |
30% |
29% |
21% |
20% |
28% |
31% |
21% |
20% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
GATA3 |
3402 |
4129 |
21% |
21% |
29% |
29% |
21% |
22% |
28% |
29% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
SRY |
5782 |
7626 |
21% |
22% |
28% |
28% |
20% |
20% |
30% |
29% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
AREB6 |
ELK1 |
4542 |
5058 |
21% |
23% |
28% |
29% |
21% |
23% |
28% |
28% |
<1E-16 |
3.30E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
AREB6 |
MZF1 |
5502 |
4366 |
23% |
21% |
29% |
27% |
23% |
22% |
29% |
27% |
<1E-16 |
4.30E-12 |
|
|
|
** |
|
|
25 50 200 |
25 |
|
AREB6 |
IK1 |
4028 |
4204 |
21% |
22% |
28% |
29% |
22% |
22% |
28% |
28% |
<1E-16 |
9.80E-14 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
PAX4 |
5413 |
6145 |
20% |
22% |
34% |
24% |
19% |
21% |
36% |
25% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
GKLF |
5518 |
6123 |
21% |
21% |
29% |
28% |
21% |
21% |
30% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
AREB6 |
3746 |
2189 |
30% |
28% |
21% |
21% |
29% |
29% |
22% |
20% |
<1E-16 |
1.70E-11 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
SP1 |
3561 |
3042 |
19% |
21% |
31% |
29% |
20% |
21% |
30% |
29% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
P300 |
3232 |
3500 |
21% |
20% |
29% |
29% |
21% |
23% |
28% |
28% |
<1E-16 |
4.00E-10 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
AREB6 |
GATA1 |
4001 |
4518 |
22% |
21% |
29% |
29% |
22% |
22% |
28% |
28% |
<1E-16 |
7.10E-15 |
**** |
|
|
|
|
|
25 50 200 |
25 50 |
|
AREB6 |
LYF1 |
6383 |
3772 |
22% |
22% |
28% |
28% |
21% |
21% |
30% |
28% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
HNF4 |
GATA3 |
8198 |
10481 |
27% |
28% |
22% |
22% |
27% |
28% |
22% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
SP1 |
7474 |
6933 |
28% |
29% |
19% |
24% |
28% |
28% |
21% |
23% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
HNF4 |
SRY |
6586 |
8127 |
29% |
29% |
20% |
22% |
28% |
29% |
20% |
23% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
HNF4 |
ELK1 |
10747 |
12259 |
27% |
27% |
22% |
23% |
27% |
27% |
23% |
23% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
HNF4 |
MZF1 |
11085 |
11253 |
28% |
30% |
20% |
22% |
28% |
30% |
20% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
HNF4 |
IK1 |
9450 |
10405 |
27% |
28% |
22% |
23% |
27% |
28% |
22% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
HOXA3 |
8165 |
9677 |
22% |
23% |
31% |
25% |
23% |
23% |
30% |
24% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
GKLF |
7011 |
7710 |
31% |
31% |
18% |
20% |
30% |
32% |
18% |
20% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
FOXD3 |
SRY |
5999 |
8490 |
18% |
18% |
32% |
31% |
13% |
15% |
37% |
35% |
<1E-16 |
<1E-16 |
|
|
* |
|
|
|
25 50 200 |
25 |
|
FOXD3 |
PAX4 |
4666 |
5132 |
17% |
19% |
40% |
23% |
16% |
17% |
45% |
23% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
FOXD3 |
GKLF |
2945 |
3244 |
21% |
20% |
29% |
31% |
18% |
18% |
37% |
28% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
GATA3 |
SP1 |
4697 |
4930 |
30% |
30% |
20% |
20% |
32% |
28% |
19% |
21% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
GATA3 |
RREB1 |
1290 |
1348 |
17% |
17% |
36% |
31% |
17% |
20% |
33% |
29% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
GATA3 |
ELK1 |
8159 |
9991 |
27% |
28% |
24% |
22% |
27% |
27% |
23% |
22% |
<1E-16 |
7.00E-15 |
|
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
GATA3 |
P300 |
5735 |
6765 |
30% |
29% |
20% |
21% |
29% |
28% |
21% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
GATA3 |
MZF1 |
8561 |
9357 |
32% |
29% |
19% |
20% |
30% |
31% |
20% |
20% |
<1E-16 |
<1E-16 |
|
|
|
* |
|
|
25 50 200 |
25 |
|
GATA3 |
GATA1 |
6972 |
8917 |
29% |
29% |
21% |
21% |
28% |
28% |
22% |
21% |
<1E-16 |
<1E-16 |
|
|
|
** |
|
|
25 50 200 |
25 |
|
GATA3 |
IK1 |
7572 |
8727 |
29% |
28% |
21% |
22% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
GATA3 |
LYF1 |
6750 |
7838 |
29% |
30% |
21% |
21% |
27% |
29% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
GATA3 |
PAX4 |
5510 |
6143 |
26% |
23% |
21% |
30% |
26% |
23% |
21% |
31% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
GATA3 |
GKLF |
5930 |
6708 |
32% |
32% |
18% |
18% |
31% |
33% |
19% |
17% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
TCF11 |
AML1 |
5633 |
7762 |
22% |
38% |
20% |
21% |
22% |
37% |
20% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
TCF11 |
ARP1 |
3177 |
4194 |
21% |
21% |
37% |
21% |
23% |
21% |
34% |
23% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 50 |
|
TCF11 |
CREBP1CJUN |
1109 |
1174 |
9% |
7% |
77% |
6% |
9% |
7% |
76% |
8% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
GR |
SRY |
6598 |
8889 |
20% |
23% |
28% |
29% |
20% |
23% |
28% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
GR |
MZF1 |
8770 |
10037 |
22% |
23% |
27% |
28% |
22% |
24% |
27% |
28% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
GR |
GKLF |
6039 |
7318 |
20% |
22% |
29% |
29% |
19% |
22% |
30% |
30% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
AML1 |
MZF1 |
6384 |
6802 |
30% |
28% |
21% |
22% |
29% |
27% |
22% |
23% |
<1E-16 |
<1E-16 |
|
|
*** |
*** |
|
|
25 50 200 |
25 50 |
|
AML1 |
LYF1 |
4440 |
5281 |
32% |
28% |
19% |
21% |
30% |
28% |
21% |
21% |
<1E-16 |
<1E-16 |
**** |
|
|
** |
|
|
25 50 200 |
25 |
|
AML1 |
PAX4 |
3131 |
3610 |
20% |
22% |
25% |
33% |
19% |
23% |
26% |
32% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
NF1 |
SRY |
5599 |
6746 |
22% |
20% |
33% |
25% |
21% |
21% |
32% |
26% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
NF1 |
GKLF |
5746 |
6007 |
23% |
21% |
30% |
26% |
22% |
21% |
31% |
26% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
ARP1 |
MZF1 |
3940 |
3634 |
20% |
23% |
27% |
30% |
23% |
22% |
26% |
29% |
<1E-16 |
2.20E-10 |
**** |
|
|
* |
|
|
25 50 |
25 |
|
ARP1 |
GKLF |
3779 |
2266 |
22% |
21% |
28% |
29% |
21% |
20% |
27% |
32% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
NKX61 |
SRY |
1857 |
1898 |
20% |
19% |
37% |
24% |
16% |
18% |
39% |
27% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
NKX61 |
PAX4 |
1600 |
1451 |
19% |
17% |
42% |
22% |
18% |
17% |
43% |
23% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
SRY |
ELK1 |
5569 |
6980 |
29% |
28% |
21% |
23% |
30% |
26% |
20% |
23% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
SRY |
LYF1 |
6055 |
6962 |
21% |
23% |
34% |
23% |
22% |
20% |
35% |
23% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
SRY |
PAX4 |
6205 |
7417 |
38% |
26% |
16% |
20% |
42% |
25% |
15% |
19% |
<1E-16 |
<1E-16 |
**** |
|
* |
** |
|
|
25 50 200 |
25 |
|
SRY |
GKLF |
4622 |
5483 |
32% |
30% |
18% |
20% |
37% |
27% |
16% |
20% |
<1E-16 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
RREB1 |
P300 |
1662 |
1312 |
16% |
17% |
36% |
31% |
16% |
18% |
37% |
30% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
RREB1 |
MZF1 |
3022 |
2326 |
15% |
17% |
38% |
30% |
13% |
13% |
44% |
30% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
RREB1 |
GATA1 |
2126 |
1784 |
17% |
17% |
38% |
27% |
18% |
16% |
38% |
28% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
RREB1 |
IK1 |
1737 |
1583 |
18% |
20% |
31% |
31% |
20% |
20% |
32% |
29% |
<1E-16 |
1.10E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
RREB1 |
LYF1 |
1550 |
1306 |
18% |
17% |
29% |
36% |
17% |
15% |
33% |
35% |
<1E-16 |
<1E-16 |
**** |
|
**** |
* |
|
|
25 50 200 |
25 |
|
RREB1 |
PAX4 |
740 |
792 |
21% |
46% |
15% |
18% |
24% |
44% |
12% |
20% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
RREB1 |
GKLF |
1362 |
1171 |
17% |
15% |
34% |
34% |
18% |
16% |
32% |
33% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
ELK1 |
ELK1 |
12232 |
13354 |
29% |
28% |
21% |
22% |
28% |
28% |
21% |
22% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
ELK1 |
P300 |
8344 |
8773 |
28% |
28% |
21% |
22% |
28% |
27% |
22% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
ELK1 |
MZF1 |
13045 |
12134 |
28% |
28% |
22% |
22% |
28% |
28% |
22% |
22% |
<1E-16 |
<1E-16 |
|
|
**** |
* |
|
|
25 50 200 |
25 |
|
ELK1 |
GATA1 |
10218 |
11440 |
28% |
28% |
23% |
22% |
27% |
27% |
22% |
24% |
<1E-16 |
1.10E-16 |
|
|
* |
|
|
|
25 50 200 |
25 50 |
|
ELK1 |
IK1 |
10178 |
10570 |
27% |
28% |
22% |
22% |
28% |
28% |
22% |
23% |
<1E-16 |
<1E-16 |
|
|
** |
|
|
|
25 50 200 |
25 50 |
|
ELK1 |
LYF1 |
8994 |
9522 |
27% |
28% |
23% |
22% |
27% |
28% |
23% |
22% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
ELK1 |
PAX4 |
12013 |
11447 |
23% |
23% |
26% |
28% |
23% |
23% |
26% |
28% |
<1E-16 |
<1E-16 |
|
|
*** |
|
|
|
25 50 200 |
25 50 |
|
ELK1 |
GKLF |
7481 |
7731 |
30% |
30% |
20% |
20% |
30% |
31% |
20% |
19% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 200 |
25 |
|
P300 |
MZF1 |
9553 |
8740 |
30% |
31% |
19% |
21% |
31% |
30% |
19% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
P300 |
CMYB |
6111 |
6853 |
27% |
29% |
22% |
22% |
26% |
27% |
24% |
23% |
<1E-16 |
1.10E-06 |
|
|
|
|
|
|
25 50 200 |
25 |
|
P300 |
GATA1 |
7376 |
7763 |
28% |
28% |
21% |
22% |
29% |
28% |
21% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
P300 |
IK1 |
7216 |
7172 |
29% |
29% |
21% |
21% |
29% |
29% |
20% |
22% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
P300 |
LYF1 |
6589 |
6508 |
29% |
31% |
20% |
20% |
28% |
31% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
**** |
* |
|
|
25 50 200 |
25 |
|
P300 |
PAX4 |
8846 |
8294 |
20% |
19% |
31% |
31% |
21% |
19% |
31% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
P300 |
GKLF |
5393 |
5558 |
31% |
33% |
17% |
19% |
29% |
33% |
18% |
20% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
MZF1 |
MZF1 |
14460 |
12208 |
33% |
33% |
17% |
18% |
34% |
33% |
16% |
16% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MZF1 |
CMYB |
9357 |
9556 |
26% |
28% |
23% |
22% |
26% |
27% |
24% |
23% |
<1E-16 |
1.00E-08 |
|
|
|
|
|
|
25 50 |
25 |
|
MZF1 |
GATA1 |
11295 |
10907 |
29% |
29% |
21% |
21% |
29% |
29% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MZF1 |
IK1 |
11360 |
10302 |
30% |
29% |
20% |
21% |
30% |
29% |
20% |
20% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MZF1 |
LYF1 |
10160 |
9177 |
29% |
31% |
20% |
20% |
29% |
32% |
20% |
20% |
<1E-16 |
<1E-16 |
|
|
**** |
** |
|
|
25 50 200 |
25 |
|
MZF1 |
HOXA3 |
7279 |
7870 |
21% |
25% |
28% |
26% |
22% |
25% |
27% |
25% |
<1E-16 |
5.20E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
MZF1 |
NKX25 |
4959 |
5448 |
27% |
29% |
22% |
22% |
26% |
28% |
23% |
23% |
<1E-16 |
5.10E-10 |
|
|
*** |
**** |
|
|
25 50 200 |
25 50 |
|
MZF1 |
PAX4 |
5304 |
5615 |
30% |
21% |
21% |
28% |
30% |
22% |
21% |
27% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MZF1 |
GKLF |
8798 |
8611 |
35% |
36% |
15% |
15% |
33% |
37% |
14% |
15% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MZF1 |
COMP1 |
7273 |
7899 |
26% |
29% |
23% |
22% |
26% |
27% |
23% |
24% |
<1E-16 |
3.90E-06 |
|
|
* |
|
|
|
25 50 |
25 |
|
CMYB |
PAX4 |
8530 |
9033 |
21% |
22% |
27% |
29% |
22% |
23% |
26% |
29% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CP2 |
PAX4 |
3602 |
4357 |
24% |
31% |
18% |
27% |
24% |
32% |
17% |
26% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
GATA1 |
IK1 |
8862 |
9297 |
27% |
27% |
22% |
23% |
28% |
27% |
22% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
GATA1 |
LYF1 |
7566 |
7974 |
29% |
29% |
21% |
22% |
27% |
29% |
21% |
22% |
<1E-16 |
<1E-16 |
|
|
**** |
* |
|
|
25 50 200 |
25 |
|
GATA1 |
PAX4 |
4292 |
4876 |
23% |
25% |
21% |
31% |
22% |
26% |
20% |
32% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
GATA1 |
GKLF |
6447 |
6834 |
29% |
33% |
19% |
20% |
28% |
34% |
19% |
19% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
SOX5 |
PAX4 |
6078 |
6188 |
27% |
29% |
21% |
23% |
27% |
29% |
21% |
23% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
IK1 |
LYF1 |
8112 |
7902 |
28% |
30% |
21% |
21% |
28% |
29% |
21% |
21% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
IK1 |
PAX4 |
10020 |
9424 |
22% |
20% |
29% |
28% |
22% |
21% |
30% |
28% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
IK1 |
GKLF |
6987 |
6833 |
31% |
32% |
18% |
20% |
30% |
33% |
19% |
19% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
LYF1 |
PAX4 |
5420 |
5654 |
27% |
19% |
27% |
27% |
25% |
19% |
28% |
27% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
LYF1 |
GKLF |
6422 |
6322 |
32% |
28% |
23% |
18% |
30% |
29% |
24% |
18% |
<1E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
HOXA3 |
GKLF |
5118 |
5564 |
24% |
20% |
29% |
27% |
23% |
22% |
28% |
27% |
<1E-16 |
2.20E-14 |
**** |
|
|
|
|
|
25 50 |
25 |
|
EN1 |
PAX4 |
5996 |
7109 |
23% |
21% |
27% |
29% |
24% |
21% |
28% |
28% |
<1E-16 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
PAX4 |
PAX4 |
3953 |
4317 |
33% |
22% |
22% |
23% |
35% |
23% |
20% |
22% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
PAX4 |
GKLF |
3972 |
4180 |
22% |
26% |
19% |
33% |
24% |
26% |
18% |
32% |
<1E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
CEBP |
MZF1 |
5921 |
6014 |
27% |
29% |
22% |
23% |
26% |
29% |
22% |
22% |
1.10E-16 |
2.20E-15 |
|
|
**** |
*** |
|
|
25 50 200 |
25 50 |
|
RORA1 |
ER |
9337 |
2939 |
22% |
23% |
27% |
28% |
21% |
21% |
27% |
32% |
1.10E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
HNF1 |
MEIS1A/HOXA9 |
8746 |
9327 |
23% |
24% |
29% |
24% |
24% |
24% |
30% |
23% |
1.10E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
NFAT |
HFH3 |
5625 |
5713 |
22% |
22% |
28% |
28% |
21% |
22% |
28% |
29% |
1.10E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
MEIS1A/HOXA9 |
HNF1 |
8305 |
8774 |
24% |
24% |
29% |
23% |
24% |
23% |
30% |
23% |
1.10E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
GATA2 |
GATA1 |
11382 |
8616 |
27% |
27% |
23% |
23% |
26% |
27% |
24% |
22% |
1.10E-16 |
9.60E-12 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
HNF4 |
RREB1 |
1762 |
1679 |
20% |
20% |
33% |
26% |
21% |
21% |
31% |
27% |
1.10E-16 |
7.40E-11 |
**** |
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
PAX4 |
9859 |
10478 |
23% |
22% |
28% |
27% |
24% |
22% |
27% |
27% |
1.10E-16 |
5.40E-15 |
|
|
|
|
|
|
25 50 |
25 |
|
AML1 |
GATA1 |
5027 |
6288 |
28% |
28% |
21% |
23% |
26% |
26% |
23% |
24% |
1.10E-16 |
0.00046 |
**** |
|
** |
**** |
|
|
25 50 |
|
|
GATA2 |
LYF1 |
6385 |
7566 |
28% |
28% |
23% |
22% |
26% |
28% |
23% |
23% |
2.20E-16 |
2.00E-11 |
|
|
|
|
|
|
25 50 |
25 |
|
1-Oct |
AML1 |
3926 |
4780 |
24% |
22% |
31% |
23% |
25% |
22% |
31% |
22% |
2.20E-16 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
AML1 |
NF1 |
4494 |
5667 |
30% |
26% |
22% |
22% |
28% |
27% |
21% |
25% |
2.20E-16 |
7.10E-11 |
**** |
|
|
* |
|
|
25 50 |
25 |
|
PAX5 |
GKLF |
2927 |
1564 |
29% |
29% |
20% |
23% |
29% |
29% |
19% |
24% |
3.30E-16 |
1.40E-09 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
SP1 |
EN1 |
3285 |
3813 |
28% |
29% |
21% |
21% |
28% |
28% |
21% |
24% |
3.30E-16 |
3.10E-10 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
YY1 |
IK1 |
5618 |
6394 |
23% |
22% |
28% |
27% |
22% |
22% |
28% |
28% |
5.60E-16 |
1.10E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
CEBP |
SP1 |
4365 |
4333 |
28% |
29% |
22% |
22% |
27% |
28% |
22% |
23% |
5.60E-16 |
2.50E-09 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
P53 |
SP1 |
8022 |
6752 |
22% |
24% |
26% |
28% |
21% |
25% |
25% |
29% |
5.60E-16 |
3.40E-15 |
|
|
*** |
** |
|
|
25 50 |
25 |
|
HFH3 |
AREB6 |
4281 |
5187 |
28% |
29% |
22% |
21% |
29% |
30% |
21% |
21% |
5.60E-16 |
<1E-16 |
**** |
|
*** |
|
|
|
25 50 200 |
25 |
|
SOX9 |
SRY |
7028 |
8266 |
28% |
28% |
23% |
22% |
28% |
29% |
21% |
22% |
7.80E-16 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
LMO2COM |
GATA1 |
5891 |
7641 |
28% |
27% |
22% |
22% |
26% |
28% |
23% |
23% |
8.90E-16 |
2.90E-14 |
|
|
|
*** |
|
|
25 50 200 |
25 50 |
|
HNF4 |
P300 |
7281 |
8354 |
27% |
27% |
22% |
23% |
27% |
27% |
23% |
23% |
1.10E-15 |
1.20E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBPB |
LYF1 |
6797 |
6472 |
27% |
28% |
23% |
22% |
27% |
27% |
23% |
23% |
1.20E-15 |
1.20E-07 |
|
|
*** |
* |
|
|
25 50 200 |
25 50 |
|
NFAT |
1-Oct |
13710 |
7689 |
27% |
27% |
23% |
23% |
26% |
28% |
23% |
23% |
1.20E-15 |
2.70E-11 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
1-Oct |
FOXD3 |
6033 |
5712 |
23% |
22% |
27% |
28% |
23% |
22% |
28% |
27% |
1.20E-15 |
1.60E-12 |
|
|
|
|
|
|
25 50 |
25 |
|
P53 |
GKLF |
4677 |
5067 |
21% |
24% |
26% |
29% |
20% |
26% |
24% |
30% |
1.30E-15 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
NFY |
LYF1 |
5067 |
5128 |
22% |
22% |
28% |
28% |
23% |
22% |
28% |
27% |
1.80E-15 |
5.20E-11 |
|
|
|
* |
|
|
25 50 200 |
25 50 |
|
PBX1 |
HNF4 |
5737 |
5867 |
28% |
27% |
21% |
24% |
29% |
27% |
22% |
22% |
1.90E-15 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
AREB6 |
HNF4 |
7683 |
9682 |
22% |
23% |
28% |
26% |
23% |
23% |
27% |
27% |
2.00E-15 |
7.30E-11 |
|
|
|
|
|
|
25 50 |
25 |
|
AP4 |
ARP1 |
3568 |
3907 |
23% |
23% |
31% |
23% |
24% |
23% |
30% |
23% |
2.10E-15 |
2.10E-12 |
**** |
|
|
|
|
|
25 50 |
25 |
|
FOXJ2 |
AREB6 |
4902 |
5812 |
22% |
22% |
28% |
28% |
21% |
21% |
28% |
29% |
3.60E-15 |
<1E-16 |
**** |
|
*** |
* |
|
|
25 50 200 |
25 |
|
NKX25 |
PAX4 |
4131 |
4478 |
23% |
24% |
23% |
31% |
21% |
25% |
22% |
32% |
3.70E-15 |
<1E-16 |
**** |
|
|
|
|
|
25 50 200 |
25 50 |
|
RREB1 |
CMYB |
1459 |
1418 |
21% |
18% |
30% |
30% |
22% |
18% |
32% |
28% |
3.90E-15 |
2.30E-14 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
LMO2COM |
HNF4 |
6996 |
9067 |
28% |
27% |
23% |
22% |
27% |
26% |
23% |
24% |
4.60E-15 |
1.00E-11 |
|
|
|
|
|
|
25 50 |
25 |
|
NKX25 |
GKLF |
5275 |
4987 |
25% |
21% |
28% |
27% |
24% |
21% |
29% |
26% |
5.30E-15 |
3.30E-16 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
LMO2COM |
ELK1 |
11197 |
8320 |
27% |
27% |
23% |
23% |
27% |
27% |
22% |
24% |
5.90E-15 |
1.30E-13 |
|
|
** |
**** |
|
|
25 50 |
25 |
|
HSF1 |
MZF1 |
8117 |
8296 |
25% |
28% |
22% |
25% |
25% |
28% |
22% |
25% |
6.40E-15 |
3.80E-13 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
SP1 |
NKX25 |
3781 |
4026 |
26% |
30% |
22% |
22% |
25% |
29% |
22% |
23% |
6.70E-15 |
3.50E-10 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
HFH3 |
1-Oct |
6060 |
6017 |
22% |
22% |
28% |
27% |
22% |
22% |
28% |
27% |
7.70E-15 |
1.10E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
AML1 |
RREB1 |
892 |
986 |
18% |
19% |
28% |
35% |
18% |
20% |
27% |
35% |
8.00E-15 |
2.60E-14 |
|
|
* |
|
|
|
25 50 200 |
25 |
|
NFAT |
GATA1 |
7140 |
7912 |
27% |
28% |
22% |
23% |
27% |
27% |
23% |
24% |
8.30E-15 |
2.00E-07 |
|
|
* |
|
|
|
25 50 |
25 |
|
GR |
ELK1 |
8329 |
11030 |
22% |
23% |
27% |
27% |
23% |
23% |
26% |
27% |
8.80E-15 |
2.70E-10 |
|
|
*** |
*** |
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
AP1 |
8364 |
9952 |
23% |
23% |
29% |
24% |
24% |
23% |
29% |
25% |
1.00E-14 |
<1E-16 |
|
|
|
|
|
|
25 |
25 |
|
CREL |
MZF1 |
9624 |
8184 |
23% |
25% |
24% |
28% |
22% |
26% |
24% |
28% |
1.20E-14 |
4.30E-13 |
|
|
*** |
|
|
|
25 50 |
25 |
|
P53 |
PAX4 |
8095 |
7847 |
28% |
26% |
24% |
22% |
28% |
25% |
25% |
22% |
1.50E-14 |
2.90E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
FOXJ2 |
NFAT |
6317 |
6391 |
27% |
28% |
23% |
22% |
28% |
28% |
22% |
22% |
1.70E-14 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
YY1 |
GATA3 |
5914 |
7416 |
22% |
22% |
28% |
28% |
22% |
22% |
28% |
27% |
1.70E-14 |
<1E-16 |
|
|
|
|
|
|
25 50 200 |
25 |
|
YY1 |
GATA1 |
9187 |
6743 |
22% |
23% |
28% |
27% |
23% |
23% |
28% |
26% |
2.20E-14 |
1.20E-13 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
FOXJ2 |
1-Oct |
6565 |
6443 |
28% |
27% |
23% |
23% |
28% |
27% |
23% |
23% |
2.30E-14 |
3.30E-11 |
|
|
|
|
|
|
25 50 |
25 |
|
COUP |
AP4 |
3134 |
3891 |
22% |
23% |
31% |
23% |
23% |
23% |
32% |
22% |
2.60E-14 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
NFAT |
GR |
8177 |
9928 |
22% |
24% |
27% |
27% |
23% |
23% |
27% |
27% |
3.00E-14 |
1.90E-14 |
|
|
|
|
|
|
25 50 |
25 |
|
NFY |
P300 |
7464 |
4518 |
23% |
22% |
28% |
26% |
23% |
23% |
28% |
25% |
3.70E-14 |
1.60E-07 |
|
|
** |
|
|
|
25 50 200 |
25 50 |
|
GATA3 |
HOXA3 |
7494 |
8937 |
23% |
24% |
29% |
24% |
23% |
24% |
29% |
25% |
4.30E-14 |
4.20E-15 |
|
|
|
|
|
|
25 50 |
25 |
|
SRY |
MZF1 |
5883 |
6825 |
25% |
29% |
23% |
23% |
28% |
28% |
22% |
23% |
4.70E-14 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
HNF1 |
PAX4 |
6016 |
5567 |
29% |
24% |
23% |
24% |
29% |
24% |
23% |
24% |
7.20E-14 |
4.90E-09 |
|
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
GR |
8118 |
11155 |
23% |
22% |
27% |
27% |
23% |
22% |
27% |
27% |
8.70E-14 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
GATA2 |
P300 |
5519 |
6587 |
28% |
28% |
23% |
22% |
27% |
27% |
22% |
23% |
9.00E-14 |
3.30E-11 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
CEBPB |
SRY |
7108 |
7701 |
25% |
23% |
29% |
24% |
24% |
23% |
28% |
25% |
9.80E-14 |
1.40E-09 |
|
|
** |
**** |
|
|
25 50 |
25 |
|
NFY |
GKLF |
4170 |
4339 |
23% |
21% |
29% |
27% |
25% |
22% |
27% |
27% |
1.00E-13 |
4.50E-06 |
**** |
|
|
** |
|
|
25 50 |
25 |
|
AP2 |
IK1 |
12092 |
9013 |
23% |
23% |
28% |
26% |
23% |
23% |
28% |
26% |
1.50E-13 |
7.50E-15 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
ZID |
SP1 |
3602 |
2878 |
22% |
22% |
28% |
29% |
22% |
23% |
27% |
28% |
1.60E-13 |
1.70E-06 |
**** |
|
**** |
**** |
|
|
25 50 200 |
25 |
|
ZID |
MZF1 |
6107 |
3000 |
23% |
22% |
28% |
27% |
22% |
23% |
28% |
28% |
1.70E-13 |
4.30E-08 |
|
|
|
|
|
|
25 50 |
25 |
|
NFY |
GATA1 |
5699 |
6419 |
23% |
22% |
28% |
27% |
23% |
24% |
28% |
25% |
1.80E-13 |
4.10E-07 |
|
|
** |
|
|
|
25 50 200 |
25 50 |
|
HFH3 |
HNF4 |
7568 |
5161 |
23% |
23% |
28% |
26% |
21% |
22% |
30% |
27% |
2.00E-13 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
MYCMAX |
PAX4 |
3749 |
4627 |
24% |
29% |
20% |
26% |
24% |
30% |
20% |
26% |
2.30E-13 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
YY1 |
NFAT |
10870 |
11369 |
24% |
23% |
27% |
27% |
24% |
24% |
26% |
26% |
2.40E-13 |
2.90E-05 |
|
|
|
|
|
|
25 50 200 |
|
|
YY1 |
ELK1 |
9848 |
7065 |
23% |
23% |
27% |
26% |
23% |
24% |
27% |
26% |
2.40E-13 |
1.20E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
SP1 |
MEIS1A/HOXA9 |
5432 |
6046 |
28% |
28% |
22% |
23% |
27% |
26% |
23% |
24% |
2.90E-13 |
2.20E-06 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
E2F |
SRY |
82 |
110 |
15% |
9% |
62% |
15% |
13% |
9% |
57% |
21% |
3.10E-13 |
7.00E-14 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
CMYB |
GATA1 |
7631 |
9104 |
28% |
27% |
23% |
23% |
26% |
26% |
24% |
24% |
3.40E-13 |
0.032 |
|
|
|
|
|
|
25 50 |
|
|
PAX5 |
MZF1 |
4164 |
3045 |
29% |
27% |
22% |
22% |
29% |
27% |
22% |
22% |
5.40E-13 |
4.00E-12 |
**** |
|
|
|
|
|
25 50 |
25 |
|
NFY |
EN1 |
6563 |
6888 |
23% |
23% |
29% |
26% |
24% |
23% |
29% |
25% |
5.90E-13 |
5.90E-12 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
GATA2 |
ELK1 |
7705 |
9483 |
27% |
27% |
23% |
23% |
27% |
27% |
23% |
24% |
6.30E-13 |
2.60E-09 |
|
|
|
* |
|
|
25 50 |
25 |
|
HNF1 |
EN1 |
9644 |
9559 |
26% |
27% |
22% |
25% |
26% |
27% |
22% |
25% |
7.50E-13 |
2.10E-14 |
|
|
|
|
|
|
25 |
25 |
|
YY1 |
LYF1 |
9133 |
5947 |
23% |
23% |
28% |
26% |
23% |
22% |
28% |
27% |
7.90E-13 |
9.70E-14 |
|
|
** |
** |
|
|
25 50 |
25 |
|
AML1 |
P300 |
7292 |
5192 |
27% |
27% |
22% |
23% |
28% |
27% |
22% |
23% |
8.00E-13 |
3.00E-13 |
|
|
**** |
** |
|
|
25 50 200 |
25 50 |
|
AP1 |
SRY |
6936 |
7807 |
24% |
23% |
29% |
24% |
24% |
24% |
29% |
23% |
8.50E-13 |
6.60E-12 |
|
|
|
|
|
|
25 |
25 |
|
ELK1 |
NKX25 |
5343 |
6738 |
27% |
28% |
22% |
23% |
26% |
27% |
24% |
23% |
8.80E-13 |
3.90E-05 |
|
|
**** |
**** |
|
|
25 50 |
|
|
PBX1 |
NKX61 |
1912 |
1706 |
21% |
21% |
31% |
28% |
20% |
20% |
32% |
27% |
1.00E-12 |
3.90E-15 |
**** |
|
|
|
|
|
25 50 |
25 |
|
AREB6 |
FOXD3 |
4111 |
4937 |
28% |
28% |
22% |
22% |
30% |
30% |
21% |
20% |
1.00E-12 |
<1E-16 |
**** |
|
**** |
|
|
|
25 50 200 |
25 |
|
TST1 |
SP1 |
2835 |
3077 |
26% |
30% |
21% |
23% |
27% |
28% |
22% |
23% |
1.10E-12 |
1.80E-07 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
GATA3 |
AML1 |
7803 |
10545 |
27% |
27% |
23% |
23% |
26% |
26% |
24% |
24% |
1.20E-12 |
0.00016 |
|
|
|
|
|
|
25 50 200 |
|
|
MYOGNF1 |
HOXA3 |
5656 |
6837 |
29% |
24% |
23% |
24% |
28% |
24% |
23% |
24% |
1.40E-12 |
4.20E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBPB |
GATA3 |
8107 |
8302 |
27% |
27% |
23% |
23% |
27% |
26% |
23% |
24% |
1.70E-12 |
2.70E-06 |
|
|
|
|
|
|
25 50 |
25 |
|
1-Oct |
LYF1 |
5630 |
6050 |
23% |
22% |
29% |
26% |
25% |
23% |
28% |
24% |
2.00E-12 |
8.80E-09 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
SRY |
NKX25 |
8812 |
9074 |
23% |
24% |
28% |
25% |
23% |
23% |
28% |
26% |
2.50E-12 |
8.90E-16 |
|
|
* |
|
|
|
25 50 |
25 |
|
CMYB |
LYF1 |
11310 |
7658 |
27% |
26% |
24% |
23% |
27% |
27% |
24% |
22% |
2.90E-12 |
3.40E-11 |
|
|
** |
|
|
|
25 50 |
25 |
|
LMO2COM |
NFAT |
7383 |
7939 |
27% |
27% |
22% |
24% |
26% |
26% |
24% |
23% |
3.30E-12 |
3.40E-05 |
|
|
|
|
|
|
25 50 |
|
|
AREB6 |
GR |
7047 |
9858 |
26% |
28% |
23% |
23% |
27% |
28% |
23% |
23% |
3.80E-12 |
1.80E-15 |
|
|
* |
|
|
|
25 50 |
25 |
|
NFY |
GATA3 |
5764 |
6498 |
22% |
23% |
28% |
27% |
24% |
23% |
28% |
25% |
3.90E-12 |
9.80E-08 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
PBX1 |
1-Oct |
7630 |
6828 |
27% |
28% |
23% |
23% |
28% |
27% |
22% |
23% |
3.90E-12 |
4.30E-13 |
|
|
|
|
|
|
25 50 |
25 |
|
AML1 |
SRY |
3378 |
4741 |
21% |
23% |
27% |
29% |
19% |
22% |
30% |
30% |
3.90E-12 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
CMYB |
10189 |
8403 |
24% |
22% |
27% |
26% |
25% |
22% |
27% |
26% |
4.00E-12 |
5.20E-10 |
|
|
* |
**** |
|
|
25 |
25 |
|
SRY |
SOX5 |
7159 |
8333 |
27% |
27% |
23% |
23% |
29% |
27% |
21% |
22% |
4.10E-12 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
PAX4 |
6895 |
8296 |
23% |
23% |
28% |
27% |
24% |
23% |
27% |
26% |
4.50E-12 |
2.00E-05 |
|
|
|
|
|
|
25 50 |
25 |
|
SRY |
CP2 |
4104 |
5487 |
28% |
27% |
20% |
25% |
29% |
27% |
19% |
25% |
6.80E-12 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
SOX9 |
PAX4 |
5899 |
6123 |
28% |
26% |
21% |
24% |
28% |
27% |
21% |
24% |
7.00E-12 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
SOX9 |
GKLF |
7736 |
5057 |
28% |
26% |
24% |
22% |
29% |
26% |
23% |
23% |
7.10E-12 |
9.30E-11 |
|
|
|
|
|
|
25 50 200 |
25 |
|
HNF1 |
MYCMAX |
4734 |
5731 |
23% |
24% |
30% |
24% |
23% |
24% |
28% |
25% |
1.00E-11 |
2.30E-09 |
|
|
|
|
|
|
25 50 |
25 |
|
LMO2COM |
LYF1 |
5724 |
6583 |
27% |
27% |
23% |
22% |
25% |
28% |
23% |
24% |
1.00E-11 |
7.60E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
CREL |
SRY |
4758 |
5634 |
22% |
23% |
27% |
28% |
22% |
23% |
26% |
29% |
1.10E-11 |
8.90E-16 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
GATA2 |
SP1 |
4418 |
4642 |
28% |
28% |
23% |
22% |
29% |
28% |
21% |
22% |
1.10E-11 |
3.30E-16 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
AREB6 |
RREB1 |
774 |
714 |
33% |
30% |
17% |
20% |
33% |
31% |
19% |
17% |
1.10E-11 |
1.30E-13 |
|
|
|
|
|
|
25 50 200 |
25 |
|
AP2 |
ELK1 |
14818 |
11915 |
24% |
23% |
27% |
26% |
23% |
24% |
26% |
26% |
1.20E-11 |
2.20E-08 |
|
|
* |
**** |
|
|
25 50 |
25 |
|
NFAT |
LYF1 |
7534 |
7645 |
26% |
28% |
24% |
22% |
26% |
27% |
24% |
23% |
1.30E-11 |
5.10E-06 |
|
|
* |
* |
|
|
25 50 |
25 |
|
SRY |
CMYB |
5333 |
6827 |
23% |
22% |
27% |
28% |
23% |
21% |
26% |
30% |
1.30E-11 |
<1E-16 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
SP1 |
CP2 |
10220 |
8267 |
22% |
24% |
27% |
26% |
24% |
24% |
26% |
25% |
1.40E-11 |
0.017 |
|
|
**** |
**** |
|
|
25 50 |
|
|
AP1FJ |
PAX4 |
4800 |
5818 |
27% |
25% |
21% |
27% |
27% |
26% |
20% |
27% |
1.40E-11 |
5.20E-14 |
**** |
|
|
|
|
|
25 |
25 |
|
ER |
MZF1 |
9986 |
10033 |
23% |
24% |
26% |
28% |
22% |
24% |
25% |
28% |
1.50E-11 |
3.70E-14 |
|
|
|
|
|
|
25 50 |
25 |
|
ZID |
LYF1 |
2178 |
2211 |
23% |
20% |
27% |
30% |
22% |
23% |
27% |
28% |
1.70E-11 |
1.30E-05 |
**** |
|
**** |
|
|
|
25 50 |
|
|
HOXA3 |
PAX4 |
6108 |
6192 |
22% |
28% |
23% |
27% |
21% |
28% |
23% |
27% |
1.70E-11 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
NF1 |
PAX4 |
4520 |
4804 |
23% |
23% |
29% |
25% |
22% |
23% |
28% |
27% |
1.80E-11 |
4.90E-10 |
**** |
|
|
|
|
|
25 50 |
25 |
|
AP2 |
NFY |
6343 |
5441 |
27% |
26% |
21% |
25% |
27% |
26% |
22% |
25% |
2.20E-11 |
0.00015 |
|
|
|
|
|
|
25 50 |
|
|
GATA3 |
CMYB |
6620 |
8576 |
25% |
29% |
24% |
22% |
25% |
27% |
24% |
24% |
2.20E-11 |
9.20E-05 |
|
|
|
* |
|
|
25 50 |
|
|
LMO2COM |
P300 |
8258 |
5702 |
27% |
27% |
24% |
22% |
27% |
27% |
22% |
23% |
2.80E-11 |
1.70E-09 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBPB |
ELK1 |
11949 |
7434 |
27% |
27% |
23% |
24% |
27% |
26% |
23% |
23% |
3.30E-11 |
7.00E-09 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
LMO2COM |
IK1 |
6365 |
7379 |
27% |
27% |
23% |
23% |
27% |
27% |
23% |
24% |
3.50E-11 |
7.70E-08 |
|
|
|
|
|
|
25 50 200 |
25 50 |
|
HSF1 |
SRY |
6156 |
7175 |
26% |
28% |
22% |
24% |
27% |
28% |
21% |
24% |
4.80E-11 |
2.20E-16 |
|
|
**** |
**** |
|
|
25 |
25 |
|
CREL |
HOXA3 |
6532 |
7028 |
27% |
23% |
28% |
22% |
27% |
23% |
28% |
23% |
6.30E-11 |
7.30E-14 |
|
|
* |
** |
|
|
25 |
25 |
|
GR |
IK1 |
7874 |
9739 |
23% |
23% |
27% |
27% |
24% |
23% |
27% |
26% |
6.50E-11 |
7.50E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
1-Oct |
MZF1 |
9970 |
5728 |
27% |
27% |
23% |
23% |
26% |
27% |
23% |
23% |
6.80E-11 |
6.20E-08 |
|
|
**** |
**** |
|
|
25 50 200 |
25 50 |
|
SP1 |
ER |
8637 |
8034 |
24% |
22% |
26% |
27% |
24% |
22% |
25% |
28% |
8.00E-11 |
1.90E-15 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
TCF11 |
EN1 |
8095 |
9804 |
26% |
27% |
22% |
25% |
26% |
27% |
22% |
25% |
1.00E-10 |
1.60E-11 |
|
|
|
|
|
|
25 |
25 |
|
LYF1 |
EN1 |
6744 |
7363 |
28% |
26% |
23% |
23% |
28% |
27% |
22% |
24% |
1.20E-10 |
2.80E-14 |
|
|
* |
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
MZF1 |
7976 |
9011 |
27% |
27% |
24% |
23% |
27% |
25% |
24% |
24% |
1.70E-10 |
0.00098 |
|
|
|
|
|
|
25 50 |
25 |
|
MSX1 |
EN1 |
8549 |
9418 |
28% |
24% |
25% |
23% |
28% |
23% |
26% |
23% |
1.80E-10 |
1.90E-13 |
|
|
|
|
|
|
25 |
25 |
|
AML1 |
CMYB |
7910 |
6221 |
26% |
27% |
24% |
22% |
27% |
27% |
24% |
22% |
2.00E-10 |
4.80E-10 |
|
|
** |
*** |
|
|
25 50 |
25 |
|
LYF1 |
NKX25 |
7973 |
9239 |
26% |
28% |
23% |
23% |
26% |
26% |
25% |
23% |
2.00E-10 |
0.00069 |
|
|
|
|
|
|
25 50 |
|
|
FOXJ2 |
HNF4 |
8330 |
5744 |
27% |
27% |
23% |
23% |
29% |
27% |
22% |
22% |
2.30E-10 |
1.90E-15 |
|
|
|
|
|
|
25 50 |
25 |
|
PAX6 |
PBX1 |
7419 |
6924 |
23% |
24% |
28% |
26% |
23% |
23% |
29% |
26% |
2.70E-10 |
8.70E-14 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBP |
AML1 |
4199 |
5180 |
27% |
28% |
22% |
23% |
28% |
28% |
21% |
23% |
3.00E-10 |
6.70E-15 |
**** |
|
|
|
|
|
25 50 200 |
25 50 |
|
TATA |
NKX25 |
7839 |
7200 |
24% |
24% |
28% |
24% |
23% |
24% |
29% |
23% |
3.10E-10 |
2.70E-13 |
|
|
|
|
|
|
25 |
25 |
|
CEBPB |
PBX1 |
6947 |
5997 |
24% |
24% |
29% |
24% |
24% |
23% |
27% |
25% |
3.60E-10 |
0.0004 |
|
|
|
|
|
|
25 50 |
|
|
CDPCR1 |
MZF1 |
5240 |
5572 |
27% |
28% |
22% |
23% |
27% |
26% |
23% |
24% |
3.60E-10 |
8.60E-06 |
|
|
* |
** |
|
|
25 |
|
|
P53 |
LYF1 |
5874 |
6357 |
22% |
24% |
27% |
27% |
23% |
24% |
25% |
27% |
3.90E-10 |
3.00E-05 |
|
|
|
|
|
|
25 50 |
|
|
HNF1 |
NFY |
6023 |
5901 |
23% |
24% |
29% |
25% |
22% |
22% |
31% |
25% |
4.00E-10 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBPB |
P300 |
5013 |
5051 |
27% |
27% |
22% |
23% |
28% |
25% |
23% |
24% |
4.20E-10 |
4.90E-08 |
|
|
** |
|
|
|
25 50 200 |
25 50 |
|
CEBPB |
RREB1 |
1747 |
1629 |
20% |
22% |
31% |
27% |
20% |
23% |
27% |
30% |
4.40E-10 |
9.70E-08 |
**** |
|
* |
|
|
|
25 50 200 |
50 |
|
NFY |
NFY |
406 |
384 |
18% |
15% |
35% |
31% |
13% |
16% |
36% |
35% |
4.50E-10 |
3.20E-15 |
* |
**** |
* |
|
|
|
50 200 |
50 |
|
CEBPB |
IK1 |
12009 |
7006 |
27% |
26% |
24% |
23% |
27% |
27% |
23% |
23% |
5.30E-10 |
4.60E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBP |
GATA3 |
6067 |
6910 |
27% |
27% |
22% |
24% |
26% |
28% |
22% |
24% |
5.30E-10 |
1.10E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
NFAT |
CEBP |
6906 |
6785 |
27% |
27% |
23% |
23% |
26% |
26% |
24% |
24% |
5.40E-10 |
0.0018 |
|
|
|
|
|
|
25 50 |
|
|
HFH3 |
GR |
7790 |
5739 |
27% |
27% |
23% |
23% |
26% |
28% |
23% |
23% |
5.50E-10 |
2.80E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
YY1 |
AREB6 |
4520 |
3090 |
27% |
28% |
22% |
23% |
28% |
27% |
23% |
22% |
5.80E-10 |
1.90E-07 |
**** |
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
MSX1 |
7464 |
9188 |
23% |
25% |
28% |
24% |
24% |
24% |
27% |
25% |
6.50E-10 |
5.70E-05 |
|
|
* |
|
|
|
25 50 |
|
|
HNF1 |
PBX1 |
8166 |
7604 |
24% |
23% |
27% |
26% |
23% |
22% |
28% |
27% |
7.70E-10 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
COUP |
GKLF |
3755 |
4427 |
22% |
23% |
28% |
28% |
22% |
23% |
27% |
28% |
7.80E-10 |
3.50E-10 |
**** |
|
|
|
|
|
50 |
50 |
|
IK1 |
NKX25 |
5129 |
5871 |
27% |
28% |
23% |
23% |
26% |
27% |
22% |
24% |
1.10E-09 |
2.60E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
TST1 |
GATA3 |
7156 |
7223 |
26% |
28% |
23% |
24% |
26% |
27% |
23% |
24% |
1.20E-09 |
6.60E-05 |
|
|
|
|
|
|
25 50 |
|
|
LMO2COM |
SRY |
5748 |
6986 |
27% |
28% |
22% |
23% |
25% |
27% |
24% |
25% |
1.20E-09 |
0.0047 |
|
|
|
|
|
|
25 50 |
|
|
YY1 |
RREB1 |
1480 |
1524 |
28% |
31% |
20% |
22% |
26% |
28% |
21% |
24% |
1.20E-09 |
0.0019 |
**** |
|
|
|
|
|
25 50 200 |
|
|
GATA2 |
IK1 |
7224 |
8407 |
27% |
27% |
23% |
23% |
27% |
26% |
23% |
24% |
1.30E-09 |
6.90E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
MYOGNF1 |
MZF1 |
10298 |
9060 |
24% |
23% |
27% |
26% |
24% |
23% |
27% |
26% |
1.40E-09 |
1.50E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
SP1 |
ARP1 |
3146 |
2784 |
24% |
21% |
27% |
29% |
25% |
21% |
25% |
30% |
1.40E-09 |
6.10E-09 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
YY1 |
HNF4 |
10178 |
7727 |
24% |
23% |
28% |
25% |
23% |
24% |
28% |
26% |
1.50E-09 |
1.50E-08 |
|
|
|
|
|
|
25 50 |
25 |
|
MSX1 |
PAX4 |
5560 |
5795 |
22% |
26% |
25% |
28% |
20% |
26% |
25% |
29% |
1.50E-09 |
<1E-16 |
|
|
|
|
|
|
25 |
25 |
|
PBX1 |
MZF1 |
3729 |
3828 |
25% |
29% |
22% |
23% |
27% |
27% |
25% |
22% |
1.70E-09 |
7.00E-06 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
CEBP |
ELK1 |
10175 |
6735 |
26% |
27% |
23% |
24% |
26% |
27% |
23% |
24% |
1.70E-09 |
6.50E-07 |
|
|
* |
|
|
|
25 50 |
25 |
|
SP1 |
COMP1 |
4814 |
5054 |
26% |
29% |
22% |
23% |
26% |
27% |
23% |
24% |
1.70E-09 |
0.00053 |
|
|
**** |
**** |
|
|
25 |
25 |
|
TST1 |
IK1 |
5913 |
5566 |
26% |
28% |
23% |
23% |
26% |
27% |
23% |
24% |
1.80E-09 |
0.0019 |
|
|
|
|
|
|
25 50 |
|
|
HNF1 |
GATA3 |
7091 |
7651 |
25% |
28% |
23% |
24% |
25% |
27% |
23% |
24% |
2.00E-09 |
2.30E-05 |
|
|
|
|
|
|
25 |
|
|
LMO2COM |
RREB1 |
1706 |
1897 |
24% |
20% |
31% |
26% |
22% |
25% |
27% |
27% |
2.10E-09 |
0.0032 |
**** |
|
|
|
|
|
25 50 |
|
|
NFY |
RREB1 |
871 |
832 |
29% |
31% |
18% |
21% |
26% |
33% |
18% |
23% |
2.20E-09 |
1.50E-07 |
|
|
*** |
|
|
|
25 50 200 |
25 |
|
USF |
MYCMAX |
10557 |
12731 |
27% |
27% |
23% |
24% |
26% |
26% |
25% |
23% |
2.20E-09 |
3.10E-06 |
|
|
** |
|
|
|
25 50 200 |
50 |
|
MEIS1A/HOXA9 |
SP1 |
4334 |
4907 |
28% |
27% |
22% |
23% |
27% |
27% |
22% |
24% |
2.20E-09 |
1.10E-08 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
CDPCR3HD |
MZF1 |
5649 |
6069 |
27% |
28% |
23% |
23% |
26% |
26% |
23% |
24% |
2.20E-09 |
0.001 |
|
|
**** |
**** |
|
|
25 50 |
|
|
PBX1 |
ELK1 |
4936 |
4782 |
27% |
28% |
22% |
23% |
27% |
26% |
23% |
24% |
2.30E-09 |
2.30E-05 |
|
|
*** |
** |
|
|
25 50 |
25 |
|
EGR1 |
SP1 |
240 |
220 |
40% |
30% |
17% |
13% |
41% |
35% |
13% |
10% |
2.50E-09 |
4.40E-14 |
|
|
*** |
*** |
|
|
25 50 |
25 |
|
CDPCR3HD |
GATA1 |
5332 |
6734 |
27% |
27% |
22% |
23% |
27% |
27% |
23% |
24% |
2.50E-09 |
4.80E-08 |
|
|
|
|
|
|
25 50 |
25 |
|
HAND1E47 |
PAX4 |
10722 |
11039 |
23% |
24% |
26% |
27% |
24% |
24% |
26% |
26% |
2.60E-09 |
1.10E-05 |
|
|
|
|
|
|
25 50 |
25 |
|
HNF4 |
LYF1 |
8322 |
9494 |
25% |
28% |
23% |
24% |
26% |
27% |
23% |
23% |
2.70E-09 |
2.70E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
AP2 |
AREB6 |
5246 |
4183 |
28% |
26% |
23% |
23% |
27% |
27% |
24% |
22% |
3.10E-09 |
1.90E-06 |
|
|
|
|
|
|
25 50 |
25 |
|
MYOGNF1 |
GKLF |
5734 |
5902 |
24% |
22% |
28% |
26% |
23% |
23% |
27% |
27% |
3.50E-09 |
4.50E-08 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBP |
IK1 |
10002 |
10517 |
27% |
27% |
23% |
24% |
26% |
26% |
24% |
24% |
3.50E-09 |
0.0078 |
|
|
|
|
|
|
25 50 |
|
|
CEBPB |
NFAT |
9278 |
8384 |
27% |
26% |
23% |
23% |
27% |
26% |
24% |
23% |
3.70E-09 |
2.40E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
NFAT |
CREL |
12177 |
12236 |
23% |
24% |
26% |
27% |
23% |
24% |
26% |
26% |
3.80E-09 |
2.70E-07 |
|
|
**** |
** |
|
|
25 50 |
50 200 |
|
RFX1 |
NFAT |
5746 |
6538 |
27% |
27% |
23% |
23% |
27% |
26% |
23% |
24% |
4.00E-09 |
8.00E-06 |
|
|
**** |
*** |
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
GKLF |
5634 |
6485 |
29% |
24% |
24% |
23% |
27% |
25% |
24% |
24% |
4.10E-09 |
0.00015 |
|
|
|
|
|
|
25 50 |
|
|
P300 |
COMP1 |
5410 |
6225 |
27% |
28% |
22% |
24% |
26% |
26% |
24% |
24% |
4.10E-09 |
0.043 |
|
|
|
|
|
|
25 50 |
|
|
AP2 |
HOXA3 |
5714 |
5488 |
28% |
24% |
22% |
26% |
28% |
24% |
22% |
26% |
4.50E-09 |
4.00E-09 |
|
|
**** |
**** |
|
|
25 |
25 |
|
FOXD3 |
NKX61 |
1461 |
1378 |
31% |
26% |
22% |
21% |
33% |
29% |
19% |
19% |
4.50E-09 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
SP1 |
HOXA3 |
5092 |
5511 |
23% |
26% |
28% |
23% |
23% |
25% |
28% |
23% |
6.00E-09 |
3.60E-09 |
|
|
**** |
**** |
|
|
25 |
25 |
|
FOXD3 |
1-Oct |
7209 |
6698 |
23% |
23% |
26% |
27% |
23% |
23% |
27% |
27% |
6.00E-09 |
3.00E-09 |
|
|
|
|
|
|
25 |
25 |
|
FOXD3 |
NF1 |
3417 |
3602 |
29% |
24% |
25% |
22% |
26% |
28% |
25% |
21% |
6.20E-09 |
9.60E-09 |
**** |
|
|
|
|
|
25 50 |
25 |
|
ZID |
GKLF |
3091 |
1752 |
22% |
23% |
26% |
29% |
19% |
24% |
26% |
30% |
6.60E-09 |
9.90E-09 |
**** |
|
|
|
|
|
25 50 |
25 |
|
GATA3 |
GR |
12512 |
16864 |
24% |
24% |
26% |
27% |
24% |
24% |
26% |
26% |
6.70E-09 |
0.00018 |
|
|
|
|
|
|
25 50 |
|
|
SP1 |
XBP1 |
1101 |
827 |
30% |
29% |
19% |
21% |
30% |
26% |
20% |
24% |
8.20E-09 |
0.0002 |
** |
|
|
** |
|
|
25 50 |
|
|
IRF1 |
MZF1 |
281 |
237 |
28% |
39% |
13% |
20% |
27% |
31% |
20% |
22% |
8.50E-09 |
0.067 |
|
|
**** |
**** |
|
|
25 |
|
|
GATA1 |
NKX25 |
4584 |
5949 |
26% |
28% |
22% |
24% |
25% |
27% |
24% |
24% |
8.90E-09 |
0.0041 |
**** |
|
* |
**** |
|
|
25 50 |
|
|
ZID |
P300 |
3743 |
2177 |
22% |
23% |
28% |
27% |
22% |
22% |
29% |
27% |
9.40E-09 |
7.10E-07 |
**** |
|
|
|
|
|
25 50 |
25 |
|
GKLF |
COMP1 |
5511 |
6150 |
26% |
28% |
24% |
22% |
25% |
29% |
24% |
22% |
1.00E-08 |
7.50E-11 |
|
|
|
|
|
|
25 50 |
25 |
|
AML1 |
CP2 |
5143 |
6346 |
23% |
23% |
26% |
28% |
24% |
23% |
27% |
27% |
1.10E-08 |
5.20E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
CMYB |
EN1 |
11361 |
13788 |
27% |
26% |
23% |
24% |
26% |
26% |
24% |
24% |
1.20E-08 |
0.00017 |
|
|
**** |
**** |
|
|
50 |
|
|
MEIS1A/HOXA9 |
GATA1 |
6978 |
8957 |
26% |
27% |
23% |
24% |
26% |
27% |
24% |
23% |
1.30E-08 |
7.50E-07 |
|
|
|
|
|
|
25 50 |
25 |
|
PBX1 |
GR |
5768 |
6278 |
24% |
22% |
27% |
26% |
24% |
22% |
26% |
27% |
1.40E-08 |
4.10E-07 |
|
|
|
|
|
|
25 |
25 |
|
SP1 |
HSF1 |
6415 |
6303 |
26% |
27% |
22% |
25% |
27% |
25% |
23% |
25% |
1.40E-08 |
5.90E-06 |
|
|
**** |
**** |
|
|
25 |
25 |
|
PAX5 |
SP1 |
4910 |
3326 |
28% |
26% |
24% |
22% |
28% |
27% |
22% |
22% |
1.50E-08 |
3.00E-08 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
AML1 |
11205 |
5815 |
24% |
23% |
27% |
26% |
23% |
23% |
27% |
27% |
1.50E-08 |
6.30E-07 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
AP2 |
CEBP |
8637 |
4665 |
24% |
23% |
27% |
26% |
24% |
22% |
28% |
26% |
1.60E-08 |
2.90E-08 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
LMO2COM |
YY1 |
5199 |
6539 |
23% |
23% |
27% |
27% |
23% |
23% |
27% |
27% |
1.60E-08 |
7.50E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
CREL |
PAX4 |
7026 |
4031 |
22% |
26% |
25% |
27% |
22% |
26% |
25% |
28% |
1.60E-08 |
2.00E-06 |
|
|
|
|
|
|
25 50 |
25 |
|
COUP |
HNF4 |
5562 |
4166 |
23% |
23% |
27% |
27% |
22% |
22% |
28% |
28% |
1.80E-08 |
6.60E-13 |
|
|
|
|
|
|
25 50 200 |
25 |
|
USF |
ARP1 |
3030 |
3445 |
24% |
23% |
30% |
23% |
21% |
25% |
31% |
22% |
2.00E-08 |
<1E-16 |
**** |
|
**** |
**** |
|
|
25 |
25 |
|
COUP |
SRY |
3856 |
4917 |
23% |
22% |
27% |
28% |
23% |
24% |
25% |
28% |
2.00E-08 |
3.00E-06 |
**** |
|
**** |
**** |
|
|
25 50 200 |
50 200 |
|
PAX2 |
MZF1 |
8027 |
8920 |
27% |
27% |
23% |
24% |
26% |
27% |
24% |
23% |
2.10E-08 |
1.80E-08 |
|
|
|
|
|
|
25 |
25 |
|
RREB1 |
ELK1 |
2070 |
1783 |
20% |
23% |
27% |
29% |
22% |
21% |
29% |
28% |
2.10E-08 |
3.40E-09 |
**** |
|
|
|
|
|
25 50 |
25 |
|
NFAT |
GATA2 |
7982 |
8567 |
26% |
27% |
24% |
23% |
26% |
26% |
24% |
24% |
2.20E-08 |
0.00044 |
|
|
|
|
|
|
25 |
|
|
HNF4 |
1-Oct |
6841 |
7840 |
23% |
24% |
28% |
25% |
24% |
24% |
27% |
25% |
2.20E-08 |
0.00014 |
|
|
|
|
|
|
25 50 |
25 |
|
CEBPB |
GATA1 |
6129 |
6656 |
27% |
27% |
23% |
23% |
27% |
26% |
23% |
24% |
2.30E-08 |
2.90E-06 |
|
|
* |
** |
|
|
25 50 |
25 |
|
HAND1E47 |
CP2 |
15222 |
17256 |
24% |
24% |
26% |
26% |
24% |
24% |
25% |
26% |
2.30E-08 |
3.80E-05 |
|
|
|
|
|
|
25 50 |
|
|
MSX1 |
GKLF |
4717 |
5260 |
25% |
22% |
28% |
25% |
24% |
23% |
28% |
25% |
2.40E-08 |
1.20E-06 |
**** |
|
|
|
|
|
25 |
25 |
|
OCT-1 |
AREB6 |
11117 |
7144 |
23% |
24% |
26% |
27% |
23% |
24% |
27% |
26% |
2.50E-08 |
9.20E-07 |
|
|
*** |
|
|
|
25 50 |
25 |
|
ARP1 |
ELK1 |
5736 |
6454 |
23% |
23% |
27% |
27% |
23% |
24% |
27% |
26% |
2.60E-08 |
3.50E-06 |
|
|
** |
**** |
|
|
25 50 |
50 |
|
HFH3 |
CMYB |
3503 |
4362 |
26% |
29% |
23% |
23% |
26% |
29% |
24% |
21% |
2.70E-08 |
1.20E-12 |
**** |
|
|
|
|
|
25 50 200 |
25 50 |
|
COUP |
MSX1 |
2617 |
3412 |
23% |
30% |
23% |
24% |
24% |
31% |
23% |
22% |
3.00E-08 |
5.80E-15 |
**** |
|
|
|
|
|
25 |
25 |
|
MZF1 |
EN1 |
6578 |
7149 |
26% |
27% |
23% |
24% |
27% |
27% |
23% |
24% |
3.00E-08 |
3.10E-07 |
|
|
**** |
**** |
|
|
25 |
25 |
|
HFH3 |
IK1 |
6568 |
4011 |
23% |
23% |
27% |
27% |
23% |
23% |
26% |
28% |
3.10E-08 |
5.60E-06 |
|
|
|
|
|
|
25 50 |
25 |
|
FOXD3 |
MZF1 |
3015 |
5819 |
22% |
25% |
24% |
30% |
23% |
24% |
27% |
26% |
3.40E-08 |
1.70E-05 |
**** |
|
**** |
**** |
|
|
25 |
50 200 |
|
FOXJ2 |
GR |
5167 |
6279 |
23% |
23% |
27% |
28% |
23% |
23% |
26% |
28% |
3.70E-08 |
6.80E-09 |
|
|
|
|
|
|
25 50 |
25 |
|
IRF1 |
SRY |
381 |
423 |
33% |
32% |
17% |
18% |
33% |
35% |
14% |
18% |
3.80E-08 |
3.00E-12 |
|
|
* |
|
|
|
25 |
25 |
|
GATA2 |
HNF4 |
7792 |
10212 |
27% |
26% |
24% |
23% |
27% |
25% |
24% |
24% |
4.30E-08 |
3.10E-05 |
|
|
|
|
|
|
25 50 |
|
|
HNF4 |
FOXD3 |
7214 |
4748 |
24% |
23% |
27% |
26% |
23% |
21% |
30% |
27% |
5.00E-08 |
<1E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
HNF1 |
MZF1 |
4839 |
5096 |
25% |
28% |
22% |
25% |
26% |
28% |
22% |
24% |
5.20E-08 |
1.10E-06 |
**** |
|
**** |
**** |
|
|
25 |
25 |
|
MYB |
PAX4 |
5709 |
6396 |
23% |
27% |
23% |
27% |
23% |
28% |
22% |
27% |
5.50E-08 |
6.60E-12 |
|
|
|
|
|
|
25 |
25 |
|
HSF1 |
PAX4 |
5021 |
5188 |
25% |
27% |
22% |
27% |
25% |
27% |
21% |
27% |
5.70E-08 |
1.00E-12 |
|
|
|
|
|
|
25 |
25 |
|
USF |
MZF1 |
10081 |
8967 |
24% |
23% |
27% |
26% |
25% |
23% |
26% |
26% |
5.90E-08 |
0.0012 |
|
|
|
|
|
|
25 |
|
|
TCF11 |
PAX4 |
5230 |
6026 |
26% |
24% |
22% |
27% |
27% |
24% |
22% |
27% |
5.90E-08 |
1.20E-08 |
|
|
|
|
|
|
25 |
25 |
|
EGR1 |
MZF1 |
149 |
127 |
45% |
24% |
12% |
19% |
44% |
30% |
13% |
13% |
7.30E-08 |
1.60E-07 |
|
|
**** |
**** |
|
|
25 |
25 |
|
GATA2 |
AREB6 |
3288 |
3984 |
22% |
23% |
28% |
27% |
24% |
22% |
28% |
27% |
7.30E-08 |
2.60E-08 |
**** |
|
|
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
LYF1 |
6623 |
8017 |
27% |
26% |
22% |
24% |
26% |
27% |
23% |
25% |
7.70E-08 |
1.60E-06 |
|
|
* |
* |
|
|
25 50 |
25 |
|
FOXD3 |
AML1 |
2255 |
2697 |
27% |
29% |
22% |
22% |
29% |
31% |
22% |
19% |
7.70E-08 |
<1E-16 |
**** |
|
|
|
|
|
25 50 |
25 |
|
GATA3 |
NKX25 |
5051 |
6411 |
26% |
28% |
24% |
22% |
26% |
26% |
24% |
24% |
8.10E-08 |
0.059 |
|
|
|
|
|
|
25 |
|
|
MYB |
MEIS1A/HOXA9 |
8713 |
11177 |
23% |
24% |
28% |
25% |
24% |
24% |
27% |
25% |
8.30E-08 |
6.20E-06 |
|
|
|
|
|
|
25 |
25 |
|
CEBP |
P300 |
4270 |
4661 |
27% |
28% |
22% |
24% |
28% |
26% |
23% |
23% |
8.50E-08 |
5.40E-06 |
**** |
|
|
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
AML1 |
4779 |
6520 |
26% |
28% |
22% |
24% |
26% |
28% |
22% |
24% |
8.50E-08 |
1.10E-10 |
|
|
|
|
|
|
25 |
25 |
|
PBX1 |
NF1 |
4621 |
4544 |
23% |
24% |
29% |
25% |
22% |
22% |
29% |
27% |
8.80E-08 |
2.40E-15 |
**** |
|
|
|
|
|
25 50 |
25 |
|
CDPCR3HD |
LYF1 |
5257 |
5924 |
27% |
27% |
23% |
23% |
26% |
27% |
23% |
24% |
9.80E-08 |
0.0019 |
|
|
|
|
|
|
25 |
|
|
AP1 |
GKLF |
8925 |
9895 |
25% |
23% |
27% |
25% |
25% |
23% |
27% |
25% |
9.90E-08 |
3.70E-05 |
|
|
|
|
|
|
25 50 |
|
|
HNF1 |
HFH3 |
6283 |
6333 |
27% |
27% |
23% |
23% |
28% |
27% |
23% |
23% |
1.00E-07 |
1.40E-11 |
|
|
|
|
|
|
25 50 |
25 |
|
MEIS1A/HOXA9 |
SRY |
7075 |
8798 |
28% |
23% |
25% |
25% |
26% |
22% |
25% |
27% |
1.00E-07 |
1.00E-07 |
|
|
|
* |
|
|
25 |
25 |
|
HFH3 |
ELK1 |
6205 |
4110 |
23% |
23% |
27% |
27% |
21% |
24% |
28% |
26% |
1.00E-07 |
9.90E-10 |
|
|
* |
*** |
|
|
25 50 |
25 |
|
GATA3 |
EN1 |
8143 |
9624 |
27% |
26% |
23% |
25% |
27% |
27% |
22% |
25% |
1.00E-07 |
1.10E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
P53 |
HNF4 |
11287 |
13818 |
23% |
25% |
26% |
27% |
24% |
25% |
25% |
26% |
1.10E-07 |
0.00017 |
|
|
|
|
|
|
25 50 |
|
|
FOXD3 |
GR |
4389 |
5138 |
27% |
27% |
24% |
22% |
26% |
28% |
24% |
22% |
1.10E-07 |
9.30E-11 |
**** |
|
|
|
|
|
25 50 |
25 |
|
HAND1E47 |
RREB1 |
1945 |
1740 |
20% |
23% |
28% |
29% |
23% |
24% |
25% |
28% |
1.10E-07 |
0.0051 |
**** |
|
|
|
|
|
25 50 |
|
|
CEBPB |
AREB6 |
5658 |
5575 |
23% |
23% |
27% |
27% |
22% |
25% |
27% |
26% |
1.20E-07 |
4.50E-07 |
|
|
|
|
|
|
25 50 |
50 |
|
HSF1 |
SP1 |
4699 |
4555 |
27% |
26% |
22% |
25% |
25% |
26% |
22% |
26% |
1.20E-07 |
1.40E-05 |
**** |
|
**** |
**** |
|
|
25 |
|
|
1-Oct |
HNF4 |
11900 |
12503 |
27% |
26% |
24% |
24% |
27% |
26% |
24% |
23% |
1.20E-07 |
5.40E-08 |
|
|
|
|
|
|
50 |
50 |
|
FOXJ2 |
HNF1 |
10737 |
6804 |
24% |
24% |
27% |
26% |
23% |
23% |
27% |
26% |
1.50E-07 |
5.90E-08 |
|
|
|
|
|
|
25 50 |
25 |
|
AP2 |
GATA2 |
6795 |
6634 |
24% |
23% |
28% |
25% |
24% |
23% |
27% |
26% |
1.60E-07 |
2.10E-07 |
|
|
**** |
**** |
|
|
25 |
25 |
|
ZID |
PAX4 |
3255 |
3031 |
28% |
27% |
23% |
22% |
28% |
27% |
23% |
22% |
1.60E-07 |
4.60E-07 |
**** |
|
|
|
|
|
25 50 |
25 |
|
ARP1 |
MSX1 |
2427 |
2989 |
24% |
30% |
23% |
23% |
25% |
30% |
23% |
23% |
1.70E-07 |
1.70E-07 |
**** |
|
|
|
|
|
25 |
25 |
|
PAX6 |
MZF1 |
6875 |
7284 |
23% |
23% |
27% |
27% |
24% |
24% |
26% |
26% |
1.80E-07 |
0.0053 |
|
|
*** |
**** |
|
|
25 |
|
|
NFAT |
HOXA3 |
13538 |
13670 |
24% |
24% |
27% |
26% |
25% |
24% |
26% |
26% |
1.80E-07 |
0.0047 |
|
|
|
|
|
|
50 |
|
|
TST1 |
P300 |
4057 |
4135 |
27% |
28% |
23% |
23% |
26% |
26% |
24% |
24% |
2.00E-07 |
0.048 |
**** |
|
|
|
|
|
25 50 |
|
|
RFX1 |
MZF1 |
7757 |
7790 |
26% |
27% |
23% |
25% |
26% |
27% |
23% |
23% |
2.00E-07 |
9.50E-08 |
|
|
|
|
|
|
25 |
25 |
|
PBX1 |
HSF1 |
5587 |
5304 |
27% |
26% |
22% |
25% |
28% |
25% |
21% |
26% |
2.00E-07 |
5.70E-10 |
|
|
|
|
|
|
25 |
25 |
|
P53 |
P300 |
9290 |
10233 |
23% |
24% |
27% |
26% |
24% |
24% |
26% |
26% |
2.00E-07 |
2.20E-05 |
|
|
|
|
|
|
25 50 |
|
|
NF1 |
HOXA3 |
5883 |
6880 |
26% |
26% |
22% |
26% |
26% |
26% |
22% |
25% |
2.10E-07 |
4.90E-08 |
|
|
|
|
|
|
25 |
25 |
|
HNF4 |
ARP1 |
5489 |
6404 |
23% |
23% |
27% |
27% |
24% |
22% |
26% |
27% |
2.10E-07 |
1.90E-07 |
|
|
|
|
|
|
50 |
50 |
|
SP1 |
GR |
6657 |
7304 |
24% |
23% |
27% |
26% |
23% |
22% |
28% |
27% |
2.20E-07 |
4.80E-15 |
|
|
**** |
**** |
|
|
25 |
25 |
|
SP1 |
1-Oct |
2111 |
4531 |
24% |
21% |
29% |
26% |
25% |
24% |
27% |
25% |
2.40E-07 |
0.036 |
**** |
|
**** |
**** |
|
|
25 |
50 |
|
CEBPB |
HNF4 |
8145 |
8654 |
27% |
26% |
23% |
24% |
27% |
27% |
23% |
23% |
2.80E-07 |
4.30E-08 |
|
|
* |
|
|
|
25 |
25 |
|
NFAT |
NKX25 |
5790 |
6256 |
28% |
26% |
24% |
23% |
27% |
26% |
23% |
24% |
2.80E-07 |
2.40E-05 |
|
|
|
|
|
|
25 50 |
|
|
HSF1 |
HNF4 |
8429 |
10255 |
26% |
27% |
22% |
25% |
27% |
27% |
23% |
24% |
2.80E-07 |
7.90E-14 |
|
|
|
|
|
|
25 50 |
25 |
|
MZF1 |
MSX1 |
6869 |
7637 |
23% |
27% |
26% |
24% |
23% |
27% |
26% |
24% |
2.80E-07 |
3.50E-07 |
|
|
** |
** |
|
|
25 |
25 |
|
PBX1 |
NKX25 |
9553 |
8482 |
23% |
24% |
27% |
26% |
23% |
23% |
28% |
26% |
2.90E-07 |
1.70E-15 |
|
|
|
|
|
|
25 |
25 |
|
SOX9 |
HFH3 |
5420 |
5802 |
23% |
23% |
28% |
26% |
23% |
22% |
29% |
26% |
2.90E-07 |
6.60E-14 |
|
|
|
|
|
|
25 50 |
25 |
|
AML1 |
ELK1 |
5955 |
7543 |
28% |
26% |
24% |
23% |
26% |
27% |
24% |
23% |
2.90E-07 |
6.40E-07 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
SP1 |
CDPCR3HD |
4078 |
4350 |
27% |
27% |
21% |
25% |
26% |
28% |
23% |
24% |
3.00E-07 |
0.00012 |
**** |
|
|
|
|
|
25 50 |
|
|
TST1 |
PAX4 |
4152 |
4383 |
23% |
22% |
28% |
26% |
24% |
23% |
26% |
27% |
3.10E-07 |
0.00012 |
**** |
|
|
|
|
|
25 50 |
|
|
GATA3 |
MSX1 |
6981 |
8471 |
23% |
24% |
28% |
25% |
22% |
26% |
28% |
24% |
3.10E-07 |
3.00E-11 |
|
|
|
|
|
|
25 |
25 |
|
CHOP |
HOXA3 |
5568 |
5733 |
28% |
24% |
23% |
25% |
27% |
24% |
24% |
25% |
3.10E-07 |
0.028 |
|
|
|
|
|
|
25 |
|
|
RFX1 |
ELK1 |
7633 |
8538 |
27% |
26% |
23% |
23% |
26% |
26% |
23% |
24% |
3.20E-07 |
0.00034 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
TGIF |
GKLF |
5032 |
5966 |
24% |
23% |
28% |
26% |
24% |
25% |
25% |
26% |
3.50E-07 |
0.075 |
|
|
|
|
|
|
50 |
|
|
TST1 |
GATA1 |
8836 |
9027 |
27% |
26% |
23% |
24% |
25% |
26% |
25% |
24% |
3.90E-07 |
0.018 |
|
|
|
|
|
|
50 |
|
|
TST1 |
RREB1 |
645 |
650 |
21% |
19% |
34% |
25% |
22% |
23% |
31% |
24% |
4.10E-07 |
0.0072 |
|
|
|
|
|
|
25 |
|
|
NMYC |
PAX4 |
1300 |
1568 |
21% |
30% |
21% |
27% |
20% |
31% |
21% |
28% |
4.10E-07 |
2.60E-11 |
**** |
|
|
|
|
|
25 50 |
25 |
|
HAND1E47 |
LYF1 |
8699 |
9597 |
27% |
25% |
24% |
24% |
27% |
26% |
24% |
23% |
4.30E-07 |
1.60E-09 |
|
|
|
|
|
|
25 |
25 |
|
XBP1 |
MZF1 |
1197 |
966 |
30% |
27% |
20% |
22% |
29% |
26% |
20% |
24% |
4.40E-07 |
0.001 |
|
|
**** |
**** |
|
|
25 50 |
|
|
NFAT |
P53 |
9401 |
10975 |
24% |
23% |
26% |
27% |
25% |
23% |
26% |
26% |
4.80E-07 |
2.90E-05 |
|
|
|
|
|
|
25 50 |
|
|
CDPCR3HD |
P300 |
7450 |
8803 |
27% |
26% |
23% |
24% |
26% |
26% |
23% |
24% |
4.80E-07 |
1.80E-05 |
|
|
|
|
|
|
50 |
|
|
NFKAPPAB65 |
GKLF |
666 |
621 |
17% |
27% |
24% |
32% |
21% |
25% |
24% |
30% |
4.90E-07 |
0.008 |
|
|
|
|
|
|
25 50 |
|
|
CDPCR3HD |
PAX4 |
5255 |
6036 |
24% |
22% |
27% |
26% |
23% |
23% |
27% |
27% |
4.90E-07 |
1.30E-09 |
|
|
|
|
|
|
25 |
25 |
|
ARP1 |
SRY |
3381 |
4190 |
23% |
22% |
28% |
27% |
23% |
23% |
27% |
28% |
4.90E-07 |
1.70E-07 |
**** |
|
**** |
*** |
|
|
25 50 |
50 |
|
HFH3 |
NKX61 |
1386 |
1391 |
31% |
26% |
21% |
22% |
30% |
30% |
21% |
19% |
5.20E-07 |
6.50E-12 |
**** |
|
|
|
|
|
25 |
25 |
|
TCF11 |
SRY |
6144 |
7757 |
26% |
24% |
23% |
27% |
25% |
25% |
23% |
27% |
5.40E-07 |
2.50E-07 |
|
|
** |
|
|
|
25 |
25 |
|
HFH3 |
HOXA3 |
5233 |
9273 |
26% |
28% |
22% |
24% |
26% |
27% |
24% |
23% |
5.50E-07 |
8.00E-07 |
|
|
|
|
|
|
25 |
50 |
|
RORA1 |
HNF4 |
4209 |
5196 |
28% |
27% |
23% |
22% |
27% |
26% |
23% |
24% |
5.80E-07 |
0.00014 |
**** |
|
|
|
|
|
25 50 |
|
|
NKX61 |
SOX5 |
1898 |
1714 |
21% |
24% |
30% |
25% |
22% |
24% |
26% |
28% |
5.90E-07 |
0.00072 |
**** |
|
|
|
|
|
25 |
|
|
SRY |
BRN2 |
7680 |
7534 |
26% |
27% |
23% |
24% |
28% |
27% |
22% |
23% |
6.10E-07 |
5.90E-14 |
|
|
**** |
|
|
|
25 |
25 |
|
RFX1 |
HNF4 |
6441 |
7848 |
27% |
27% |
23% |
23% |
27% |
26% |
24% |
24% |
6.40E-07 |
0.0011 |
|
|
**** |
|
|
|
25 |
|
|
NFY |
AML1 |
5948 |
7105 |
23% |
23% |
27% |
27% |
24% |
24% |
26% |
26% |
7.10E-07 |
0.0056 |
|
|
** |
**** |
|
|
50 |
|
|
SP1 |
HAND1E47 |
10219 |
9395 |
26% |
27% |
24% |
23% |
25% |
27% |
24% |
24% |
7.30E-07 |
0.0009 |
|
|
**** |
**** |
|
|
25 |
|
|
TST1 |
ELK1 |
9607 |
9617 |
26% |
27% |
23% |
24% |
26% |
26% |
24% |
23% |
7.30E-07 |
9.30E-06 |
|
|
** |
|
|
|
50 |
|
|
MYB |
RREB1 |
1393 |
1490 |
27% |
29% |
19% |
24% |
26% |
28% |
21% |
26% |
7.60E-07 |
0.0011 |
**** |
|
|
|
|
|
25 |
|
|
GR |
HOXA3 |
7437 |
9759 |
28% |
25% |
24% |
23% |
27% |
26% |
24% |
24% |
7.60E-07 |
1.00E-05 |
|
|
|
|
|
|
25 |
|
|
SP1 |
AHRARNT |
4842 |
1030 |
28% |
26% |
24% |
22% |
32% |
27% |
20% |
22% |
7.70E-07 |
1.60E-07 |
|
|
* |
** |
|
|
50 200 |
25 |
|
TST1 |
LYF1 |
9480 |
9089 |
26% |
27% |
24% |
24% |
26% |
26% |
25% |
23% |
8.00E-07 |
0.0002 |
|
|
** |
** |
|
|
25 50 |
|
|
CDPCR1 |
PAX4 |
4800 |
5484 |
24% |
22% |
27% |
27% |
24% |
23% |
26% |
27% |
8.60E-07 |
0.00012 |
|
|
|
|
|
|
25 50 |
|
|
CDPCR3HD |
RREB1 |
1424 |
1558 |
22% |
21% |
27% |
30% |
23% |
25% |
26% |
26% |
8.80E-07 |
0.29 |
**** |
|
|
|
|
|
50 |
|
|
USF |
TCF11 |
6896 |
9152 |
25% |
24% |
28% |
24% |
25% |
25% |
27% |
23% |
9.20E-07 |
5.40E-07 |
|
|
**** |
**** |
|
|
25 |
25 |
|
CEBPB |
AP2 |
4739 |
4269 |
23% |
23% |
27% |
27% |
24% |
25% |
26% |
25% |
9.30E-07 |
0.18 |
|
|
**** |
**** |
|
|
25 |
|
|
FOXD3 |
HOXA3 |
5091 |
5053 |
25% |
28% |
23% |
24% |
25% |
28% |
23% |
23% |
9.30E-07 |
1.20E-07 |
|
|
|
|
|
|
25 |
25 |
|
NFKAPPAB65 |
MZF1 |
1213 |
989 |
19% |
28% |
23% |
29% |
22% |
26% |
24% |
28% |
9.40E-07 |
0.044 |
|
|
|
|
|
|
25 |
|
|
CEBP |
AREB6 |
2667 |
2887 |
24% |
21% |
28% |
27% |
22% |
23% |
29% |
26% |
9.40E-07 |
7.90E-08 |
**** |
|
|
|
|
|
25 50 |
25 |
|
AP4 |
SP1 |
10397 |
8219 |
24% |
24% |
27% |
25% |
25% |
23% |
27% |
25% |
9.70E-07 |
0.00075 |
|
|
**** |
**** |
|
|
25 |
|
|
TCF11 |
ELK1 |
8268 |
10911 |
24% |
24% |
28% |
25% |
24% |
25% |
26% |
25% |
9.70E-07 |
0.00081 |
|
|
* |
* |
|
|
25 |
|
|
ZID |
GATA1 |
2649 |
2998 |
22% |
22% |
28% |
28% |
23% |
22% |
28% |
26% |
9.80E-07 |
2.60E-06 |
**** |
|
|
|
|
|
25 50 200 |
25 |
|
PAX5 |
HNF4 |
4100 |
4252 |
25% |
28% |
22% |
25% |
26% |
27% |
23% |
23% |
9.90E-07 |
0.0002 |
**** |
|
|
|
|
|
25 50 |
|
|
RFX1 |
GR |
5509 |
7725 |
23% |
23% |
27% |
27% |
24% |
24% |
26% |
26% |
1.00E-06 |
0.021 |
|
|
**** |
**** |
|
|
25 50 |
25 |
|
FOXD3 |
SOX5 |
5605 |
5849 |
23% |
23% |
27% |
27% |
22% |
23% |
29% |
27% |
1.00E-06 |
2.30E-15 |
|
|
|
|
|
|
25 |
25 |
|
RORA1 |
MZF1 |
2854 |
2794 |
25% |
29% |
23% |
23% |
25% |
31% |
22% |
22% |
1.10E-06 |
8.00E-13 |
**** |
|
|
|
|
|
25 50 |
25 |
|
SP1 |
PAX2 |
5900 |
6258 |
26% |
28% |
23% |
23% |
27% |
27% |
23% |
23% |
1.10E-06 |
2.80E-08 |
|
|
**** |
**** |
|
|
25 |
25 |
|
RREB1 |
CP2 |
3620 |
2926 |
28% |
26% |
23% |
23% |
27% |
26% |
23% |
24% |
1.10E-06 |
0.0027 |
**** |
|
|
|
|
|
50 |
|
|
NFY |
IK1 |
5714 |
5837 |
23% |
24% |
26% |
27% |
23% |
23% |
27% |
27% |
1.30E-06 |
6.70E-07 |
|
|
** |
|
|
|
25 50 |
25 |
|
RFX1 |
RFX1 |
7787 |
9391 |
27% |
26% |
23% |
24% |
27% |
26% |
24% |
24% |
1.30E-06 |
3.90E-06 |
|
|
|
|
|
|
50 |
50 |
|
MYOGNF1 |
PAX4 |
10249 |
9515 |
25% |
27% |
24% |
24% |
25% |
27% |
24% |
24% |
1.40E-06 |
5.70E-05 |
|
|
|
|
|
|
25 50 |
|
|
GR |
SP1 |
5395 |
9669 |
22% |
25% |
28% |
25% |
23% |
25% |
27% |
25% |
1.40E-06 |
1.50E-06 |
|
|
**** |
**** |
|
|
25 |
50 |
|
LMO2COM |
HOXA3 |
11203 |
7874 |
24% |
25% |
27% |
25% |
23% |
24% |
27% |
26% |
1.40E-06 |
1.80E-06 |
|
|
|
|
|
|
50 |
25 |
|
NF1 |
CMYB |
10898 |
13076 |
27% |
26% |
24% |
24% |
27% |
26% |
24% |
24% |
1.50E-06 |
6.10E-10 |
|
|
|
|
|
|
50 |
50 |
|
ARP1 |
HOXA3 |
4295 |
5182 |
28% |
26% |
23% |
23% |
27% |
26% |
23% |
24% |
1.50E-06 |
0.0015 |
**** |
|
|
|
|
|
50 |
|
|
NFKAPPAB65 |
CREL |
4139 |
3809 |
27% |
27% |
24% |
22% |
26% |
26% |
25% |
23% |
1.50E-06 |
0.007 |
**** |
|
|
|
|
|
200 |
|
|
GR |
PAX4 |
5199 |
6252 |
22% |
26% |
26% |
26% |
20% |
26% |
26% |
28% |
1.60E-06 |
<1E-16 |
|
|
|
|
|
|
25 |
25 |
|
ER |
GKLF |
5595 |
6296 |
22% |
24% |
26% |
27% |
23% |
24% |
24% |
28% |
1.60E-06 |
1.00E-08 |
|
|
|
|
|
|
25 |
25 |
|
MEIS1A/HOXA9 |
GATA3 |
13269 |
16497 |
25% |
27% |
24% |
24% |
26% |
25% |
25% |
24% |
1.70E-06 |
0.02 |
|
|
|
|
|
|
25 50 |
|
|
CEBP |
PBX1 |
7556 |
7008 |
25% |
23% |
27% |
25% |
23% |
23% |
29% |
25% |
1.80E-06 |
1.10E-16 |
|
|
|
|
|
|
25 |
25 |
|
FOXJ2 |
SOX9 |
9774 |
6431 |
27% |
26% |
24% |
23% |
27% |
27% |
22% |
23% |
1.80E-06 |
1.30E-10 |
|
|
|
|
|
|
25 50 |
25 |
|
LMO2COM |
1-Oct |
7066 |
7283 |
26% |
27% |
23% |
23% |
26% |
27% |
24% |
23% |
1.80E-06 |
1.60E-06 |
|
|
|
|
|
|
25 |
25 |
|
AP1FJ |
SRY |
5566 |
7372 |
27% |
26% |
22% |
26% |
26% |
25% |
22% |
27% |
1.80E-06 |
3.10E-10 |
|
|
**** |
**** |
|
|
25 |
25 |
|
CDPCR3HD |
SP1 |
5618 |
5920 |
27% |
26% |
22% |
24% |
26% |
26% |
24% |
23% |
1.80E-06 |
0.0039 |
|
|
|
|
|
|
25 50 |
|
|
RORA1 |
GKLF |
8070 |
8967 |
27% |
26% |
23% |
24% |
26% |
27% |
23% |
24% |
1.80E-06 |
8.90E-08 |
|
|
|
|
|
|
200 |
200 |
|
LMO2COM |
AREB6 |
2932 |
3529 |
22% |
23% |
28% |
26% |
23% |
22% |
27% |
28% |
1.90E-06 |
2.60E-07 |
**** |
|
|
|
|
|
25 |
25 |
|
FOXJ2 |
ELK1 |
4370 |
4977 |
27% |
27% |
23% |
23% |
27% |
26% |
23% |
24% |
2.00E-06 |
5.50E-06 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
EGR1 |
PAX4 |
117 |
124 |
15% |
13% |
27% |
44% |
11% |
14% |
33% |
42% |
2.00E-06 |
3.10E-07 |
|
|
**** |
**** |
|
|
25 |
25 |
|
NKX61 |
GKLF |
837 |
759 |
22% |
19% |
32% |
26% |
18% |
21% |
36% |
25% |
2.00E-06 |
2.70E-12 |
|
|
|
|
|
|
25 |
25 |
|
SOX9 |
FOXD3 |
5364 |
5617 |
23% |
24% |
27% |
27% |
23% |
22% |
29% |
26% |
2.20E-06 |
2.20E-16 |
|
|
|
|
|
|
25 |
25 |
|
AREB6 |
CMYB |
10586 |
13306 |
26% |
27% |
24% |
24% |
26% |
26% |
24% |
24% |
2.20E-06 |
5.40E-05 |
|
|
*** |
** |
|
|
50 |
|
|
1-Oct |
ELK1 |
10489 |
11111 |
27% |
26% |
24% |
24% |
27% |
26% |
24% |
23% |
2.30E-06 |
1.30E-06 |
|
|
|
|
|
|
25 50 |
50 |
|
HAND1E47 |
SRY |
6042 |
7899 |
23% |
24% |
26% |
27% |
22% |
24% |
26% |
27% |
2.30E-06 |
2.20E-11 |
|
|
**** |
**** |
|
|
25 |
25 |
|
RREB1 |
EN1 |
883 |
1036 |
19% |
23% |
30% |
28% |
22% |
19% |
30% |
29% |
2.30E-06 |
8.80E-08 |
|
|
**** |
**** |
|
|
25 |
25 |
|
ZID |
IK1 |
4451 |
4534 |
23% |
23% |
27% |
27% |
24% |
24% |
26% |
26% |
2.40E-06 |
0.31 |
**** |
|
|
|
|
|
50 |
|
|
PAX2 |
PAX4 |
10669 |
13572 |
25% |
27% |
24% |
24% |
27% |
26% |
24% |
24% |
2.40E-06 |
1.70E-06 |
|
|
|
|
|
|
50 |
50 |
|
HFH3 |
SOX5 |
9161 |
6126 |
24% |
23% |
27% |
26% |
22% |
23% |
29% |
26% |
2.50E-06 |
7.80E-16 |
|
|
|
|
|
|
25 50 |
25 |
|
RFX1 |
CREL |
5743 |
6158 |
24% |
23% |
25% |
28% |
24% |
24% |
26% |
27% |
2.60E-06 |
0.00011 |
|
|
|
|
|
|
25 |
|
|
FOXD3 |
ELK1 |
3542 |
3913 |
23% |
23% |
27% |
27% |
22% |
24% |
28% |
27% |
2.70E-06 |
1.00E-08 |
**** |
|
**** |
**** |
|
|
25 50 |
25 |
|
USF |
SP1 |
11491 |
9503 |
24% |
24% |
27% |
26% |
24% |
24% |
26% |
26% |
2.90E-06 |
0.00099 |
|
|
|
|
|
|
25 |
|
|
MEIS1A/HOXA9 |
ELK1 |
7956 |
10132 |
27% |
26% |
24% |
23% |
25% |
26% |
24% |
24% |
2.90E-06 |
0.069 |
|
|
|
* |
|
|
25 50 |
|
|
1-Oct |
GR |
7278 |
8116 |
24% |
23% |
27% |
26% |
24% |
23% |
26% |
27% |
2.90E-06 |
2.90E-06 |
|
|
|
|
|
|
25 |
25 |
|
HNF1 |
GKLF |
4634 |
4762 |
25% |
28% |
24% |
23% |
25% |
29% |
22% |
24% |
2.90E-06 |
3.50E-11 |
|
|
|
|
|
|
25 |
25 |
|
AML1 |
NKX25 |
3117 |
4382 |
25% |
25% |
29% |
22% |
26% |
23% |
27% |
23% |
3.00E-06 |
3.70E-05 |
**** |
|
|
|
|
|
25 |
|
|
MYOGNF1 |
HNF4 |
7972 |
9191 |
24% |
23% |
27% |
26% |
23% |
24% |
26% |
27% |
3.10E-06 |
1.90E-05 |
|
|
|
|
|
|
25 |
|
|
MYCMAX |
SRY |
4490 |
6220 |
27% |
27% |
23% |
23% |
27% |
26% |
23% |
24% |
3.10E-06 |
3.10E-06 |
**** |
|
**** |
**** |
|
|
25 |
25 |
|
MYB |
CMYB |
12484 |
15605 |
23% |
24% |
26% |
26% |
24% |
24% |
26% |
25% |
3.20E-06 |
5.10E-05 |
|
|
|
|
|
|
50 |
|
|
CDPCR3HD |
GATA3 |
10658 |
13038 |
27% |
26% |
24% |
23% |
26% |
26% |
23% |
24% |
3.30E-06 |
6.10E-07 |
|
|
|
|
|
|
50 |
50 |
|
RFX1 |
IK1 |
10600 |
11755 |
26% |
26% |
23% |
24% |
26% |
26% |
24% |
24% |
3.40E-06 |
4.70E-05 |
|
|
|
|
|
|
25 50 |
50 |
|
RREB1 |
SOX5 |
729 |
849 |
33% |
21% |
23% |
22% |
27% |
27% |
22% |
24% |
3.40E-06 |
0.071 |
|
|
|
|
|
|
25 |
|
|
FOXJ2 |
IK1 |
7314 |
7892 |
27% |
26% |
24% |
23% |
27% |
26% |
23% |
24% |
3.40E-06 |
9.90E-07 |
|
|
|
|
|
|
50 |
50 |
|
NF1 |
EN1 |
6486 |
7419 |
26% |
27% |
23% |
25% |
27% |
25% |
23% |
25% |
3.50E-06 |
2.20E-05 |
|
|
**** |
**** |
|
|
25 |
|
|
COUP |
MZF1 |
6063 |
6537 |
24% |
23% |
26% |
27% |
23% |
24% |
27% |
27% |
3.50E-06 |
6.80E-07 |
|
|
|
|
|
|
50 |
50 |
|
AREB6 |
NF1 |
10377 |
12394 |
26% |
26% |
23% |
24% |
26% |
27% |
24% |
24% |
3.50E-06 |
3.80E-07 |
|
|
* |
**** |
|
|
50 |
50 |
|
P300 |
NKX25 |
3755 |
4756 |
26% |
28% |
23% |
23% |
26% |
27% |
24% |
23% |
3.60E-06 |
0.00065 |
**** |
|
*** |
* |
|
|
25 50 |
|
|
NFAT |
IRF1 |
422 |
410 |
32% |
30% |
21% |
17% |
26% |
31% |
22% |
21% |
3.80E-06 |
0.023 |
|
|
|
|
|
|
25 |
|
|
CEBP |
HNF4 |
6415 |
7395 |
27% |
26% |
23% |
24% |
27% |
26% |
24% |
23% |
3.80E-06 |
3.80E-07 |
|
|
|
|
|
|
25 |
25 |
|
AML1 |
GKLF |
6353 |
7720 |
27% |
26% |
24% |
23% |
25% |
27% |
25% |
23% |
3.90E-06 |
0.0001 |
|
|
|
|
|
|
50 |
|
|
AML1 |
IK1 |
5151 |
6252 |
26% |
27% |
23% |
24% |
28% |
26% |
22% |
24% |
4.00E-06 |
3.40E-09 |
|
|
|
|
|
|
25 50 |
25 |
|
HOXA3 |
COMP1 |
7624 |
8467 |
25% |
23% |
27% |
25% |
24% |
24% |
27% |
25% |
4.20E-06 |
3.90E-05 |
|
|
|
|
|
|
25 |
|
|
HFH3 |
AML1 |
2364 |
3056 |
27% |
28% |
24% |
21% |
28% |
29% |
22% |
20% |
4.40E-06 |
5.60E-16 |
**** |
|
|
|
|
|
25 |
25 |
|
AP1FJ |
MSX1 |
6973 |
9392 |
24% |
25% |
27% |
23% |
23% |
26% |
27% |
24% |
4.50E-06 |
6.40E-09 |
|
|
|
|
|
|
25 |
25 |
|
MYOGNF1 |
AP4 |
9786 |
9770 |
25% |
24% |
27% |
25% |
24% |
23% |
28% |
24% |
4.60E-06 |
5.40E-10 |
|
|
|
|
|
|
25 |
25 |
|
HNF4 |
NF1 |
12726 |
15048 |
24% |
24% |
26% |
26% |
25% |
23% |
26% |
26% |
5.00E-06 |
7.50E-07 |
|
|
|
|
|
|
50 |
50 |
|
LMO2COM |
HNF1 |
6574 |
7004 |
27% |
25% |
23% |
24% |
27% |
26% |
23% |
25% |
5.20E-06 |
0.00016 |
|
|
|
|
|
|
25 |
|
|
COUP |
ELK1 |
3223 |
4107 |
22% |
24% |
28% |
26% |
23% |
25% |
27% |
26% |
5.70E-06 |
0.002 |
**** |
|
**** |
**** |
|
|
25 |
|
|
AML1 |
HAND1E47 |
5792 |
7615 |
26% |
27% |
23% |
23% |
26% |
27% |
24% |
23% |
5.70E-06 |
2.00E-06 |
|
|
|
|
|
|
25 50 |
25 |
|
MYCMAX |
ARP1 |
2367 |
3088 |
24% |
24% |
30% |
23% |
23% |
24% |
29% |
24% |
5.80E-06 |
9.50E-06 |
**** |
|
|
|
|
|
25 |
|
|
CEBP |
GATA1 |
5953 |
7043 |
27% |
25% |
23% |
24% |
27% |
26% |
24% |
24% |
5.90E-06 |
2.90E-05 |
|
|
** |
** |
|
|
25 50 |
25 |
|
SRY |
EN1 |
7707 |
8895 |
25% |
23% |
25% |
27% |
24% |
23% |
25% |
28% |
6.00E-06 |
1.50E-09 |
|
|
|
*** |
|
|
25 |
25 |
|
ELK1 |
COMP1 |
12017 |
14397 |
26% |
26% |
24% |
24% |
25% |
26% |
25% |
25% |
6.00E-06 |
0.26 |
|
|
* |
* |
|
|
50 |
|
|
PAX6 |
NFAT |
8693 |
8717 |
24% |
23% |
26% |
26% |
24% |
23% |
27% |
26% |
6.10E-06 |
2.10E-06 |
|
|
|
|
|
|
25 |
25 |
|
NFAT |
RREB1 |
2068 |
2076 |
23% |
22% |
26% |
29% |
23% |
23% |
26% |
27% |
6.10E-06 |
0.018 |
**** |
|
|
|
|
|
25 50 |
|
|
MYOGNF1 |
SP1 |
9050 |
7202 |
24% |
23% |
27% |
25% |
24% |
25% |
27% |
25% |
6.40E-06 |
0.0041 |
|
|
**** |
**** |
|
|
25 |
|
|
PAX5 |
GATA3 |
2769 |
3242 |
29% |
26% |
23% |
23% |
26% |
26% |
23% |
24% |
6.40E-06 |
0.0097 |
**** |
|
|
|
|
|
50 |
|
|
RFX1 |
SRY |
4321 |
5544 |
27% |
27% |
23% |
23% |
27% |
28% |
22% |
23% |
6.60E-06 |
1.30E-14 |
**** |
|
**** |
**** |
|
|
25 |
25 |
|
MEIS1A/HOXA9 |
NF1 |
6628 |
8181 |
25% |
26% |
23% |
27% |
26% |
25% |
24% |
24% |
6.70E-06 |
0.012 |
|
|
|
|
|
|
25 |
|
|
HNF1 |
P53 |
4128 |
4856 |
24% |
23% |
28% |
24% |
24% |
25% |
28% |
24% |
6.80E-06 |
0.00067 |
**** |
|
|
|
|
|
25 |
|
|
CEBP |
RREB1 |
1648 |
1777 |
20% |
24% |
27% |
29% |
22% |
24% |
26% |
28% |
7.70E-06 |
0.0011 |
**** |
|
* |
|
|
|
25 50 |
50 |
|
|
|
total n |
total n mm |
% of each pattern hs[9] |
|
% of each pattern mm[10] |
|
Chi2 test[11] |
expression p value[12] |
TSS position bias[13] |
order p value (binomial) |
maxd[14] |
|
name 1[15] |
name 2[16] |
hs |
mm |
5'-3' |
3'-5' |
3'-3' |
5'-5' |
5'-3' |
3'-5' |
3'-3' |
5'-5' |
p hs |
p mm |
hs |
mm |
hs |
mm |
hs |
mm |
hs |
mm |
|
|
|
NOTES: |
|
|
A) Click on
header for brief explanation of entries in each column |
|
B)
Statistical significance:* = "p<0.01", ** = "p<0.001", *** = "p<0.0001", **** = "p<0.00001" |
|
C) A gray
shade in the TF names (columns 1 and 2) indicates that the order/orientation
pattern was conserved between hs
(humans) and mm (mouse,
e.g. AP2-SP1 was significant both in hs and mm but
TCF11-ARP1 was significant only in hs) |
|
D) When an
interaction was observed for multiple maxd values, here we report the
values corresponding to the minimum Chi2 p value (i.e. the strongest evidence) |
|
E)
Entries marked in red correspond to the examples discussed in the text (Due
to note D, the values reported here may not be the same as those quoted in
the main text which may correspond to a different maxd) |
|
F) For hs, 77% of the TF pairs reported here
showed significant pattern biases for more than one value of maxd |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|