Reading Assignements

Bi/CNS 163. Sleep and Dreams.

Winter 2000

Reading Assignments

You can pick up a copy of the papers in Beckman Institute, Room 23. If there are none, please email gabrielk@caltech.edu

Jan. 11. Sleep and memory

Dependence on REM sleep of overnight improvement of a perceptual skill. Karni, A., Tanne, D., Rubenstein, B.S., Askenasy, J.J.M. and Sagi, D. (1994) Science 265, 679-681.
Reactivation of Hippocampal Ensemble Memories During Sleep. Wilson, M.A. and McNaughton, B.L. (1994) Science 265, 676-679.

Suggested reading:

Skaggs, W. E. and B. L. McNaughton (1996). "Replay of neuronal firing sequences in rat hippocampus during sleep following spatial experience." Science 271: 1870-1873.

Smith, C. (1996). "Sleep States, Memory Processes and Synaptic Plasticity." Behavioural Brain Research 78: 49-56.

Crick, F. and G. Mitchison (1983). "The function of dream sleep." Nature 304: 111-114.

Hopfield, J. J., D. I. Feinstein, et al. (1983). "'Unlearning' has a stabilizing effect in collective memories." Nature 304: 158-159.

Brown, D. W. (1996). "Autism, Asperger's Syndrome and the Crick-Mitchison Theory of the Biological Function of REM sleep." Medical Hypotheses 47: 399-403.

Jan. 18. Sleep deprivation

Physiological correlates of prolonged sleep deprivation effects in rats. Rechtschaffen, A., Gilliland, M.A., Bergmann, B.M. and Winter, J.B. (1983) Science 221, 182-184.

Suggested reading:

Horne, J. (1988). Why we sleep: The functions of sleep in humans and other mammals. Oxford, Oxford University Press.

Everson, C. A. (1995). "Functional Consequences of sustained sleep deprivation in the rat." Behavioral Brain Research 69: 43-54.

Ross, J. J. (1965). "Neurological findings after prolonged sleep deprivation." Archives of Neurology 12: 399-403.

Jan. 25. Lucid dreaming

Lucid dreaming verified by volitional communication during rem sleep. La Berge, S.P., Dement, W.C., Nagel, L.E. and Zarcone, V.P. (1981) Perceptual and motor skills 52, 727-732

Suggested reading:

LaBerge, S. (1985). Lucid Dreaming. New York, Ballantine books.

LaBerge, S. (1990). Exploring the world of lucid dreaming. New York, Ballantine books.

Feb. 01. Brain and sleep

Functional neuroanatomy of human rapid eye movement sleep and dreaming. Macquet, P. and Franck, G. (1996) Nature 383, 163-166.
Adenosine : a mediator of the sleep-inducing effects of prolonged wakefulness.PorkkaHeiskanen, T., Strecker, R.E., Thakkar, M., Bjorkum, A.A., Green, R.W. and McCarley, R.W. (1997). Science 276, 1265-1268.

Suggested reading:

Braun, A. R. and P. Herscovitch (1998). "Dissociated pattern of activity in visual corties and their projections during human rapid eye movement sleep." Science 279: 91-95.

Hobson, J. A., E. F. Pace-Schott, et al. (1998). "To dream or not to dream ? Relevant data from new neuroimaging and electrophysiological studies." Current Opinion in Neurobiology. 8: 239-244.

Mechoulam, R., E. Fride, et al. (97). "Anandamide may mediate sleep induction." Nature 389: 25-27.

McCormick, D. A. and T. Bal (1997). "Sleep and arousal: thalamocortical mechanisms." Annual review of neuroscience 20: 185-215.

Steriade, M., D. A. McCormick, et al. (1993). "Thalamocortical oscillations in the sleeping and aroused brain." Science 262: 679-685.

Feb. 08. Evolution

Mukhametov L.M. Sleep in Marine Mammals. Exp. Brain. Res. Suppl. 8:227-237, (1984)

Suggested reading:

Kavanau, J. L. (1997). "Memory, sleep and the evolution of mechanisms of synaptic efficacy maintenance." Neuroscience 79: 7-44.

Tobler, I. (1995). "Is sleep fundamentally different between mammalian species ?" Behavioral Brain Research 69: 35-41.

Hobson, J. (1995). Sleep. New York, Scientific American Library.

Feb. 15. Circadian rythms, hibernation and sleep

Are ground squirrels sleep deprived during hibernation? Trachsel L., Edgar, D.M., Heller, H.C. (1991) American Journal of Physiology. 260 (6) :1123-1129.

Suggested reading:

Horne, J. (1988). Why we sleep: The functions of sleep in humans and other mammals. Oxford, Oxford University Press.

Hobson, J. (1995). Sleep. New York, Scientific American Library.

Feb 22. Molecular biology of sleep

Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation. Chemelli R., Willie, J., Sinton, C., Elmquist, J., Scammell, T., Lee, C., Richardson, J., Williams, S., Xiong, Y., Kisanuki, Y., Fitch, T., Nakazato, M., Hammer, R., Saper, C. and Yanagisawa, M. Cell 98:437-451, (1999)
Narcolepsy: A key role for hypocretins (orexins). Siegel J. Cell 98:409-412, (1999)

Suggested reading:

Siegel, J. (2000). "Narcolepsy." Scientific American Jan.

Kryger, M., T. Roth, et al. (1994). Principles and Practice of Sleep Medicine. Philadelphia, W.B. Saunders Company.

Feb 29. Sleep and brain injury

Paper to be determined

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