MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia - Full text - MIT Libraries
SA Armstrong, JE Staunton, LB Silverman, R Pieters … - Nature Genetics, 2002 - nature.com
... Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4:11 ... M.
Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. ...
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Deregulated homeobox gene expression in cancer: cause or consequence? - Full text - MIT Libraries
C Abate-Shen - Nature Reviews Cancer, 2002 - nature.com
... 8. Chen, F. & Capecchi, MR Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9 ... D.,
Busslinger, M. & Aguzzi, A. Deregulated expression of PAX5 in medulloblastoma ...
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Homeobox genes: a molecular link between development and cancer
I PhD, II Dentist, TIIID Student - scielo.br
... Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation
t(7 ... Nutt SL, Eberhard D, Horcher M. Pax5 determines the identity of B cells from ...
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The role of homeobox genes in hematopoiesis
MC Magli - Biotherapy, 1998 - ingentaconnect.com
... HOXA9 t(7;11)(p15;p15) AML HOX11 t (10q24) breakpoints T-ALL PAX5 t (9p13) breakpoints
NHL PBX1 t(1;19) pre-B-ALL LH2 Aberrant expression CML b. Murine ...
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Comprehensive genotypic analysis of leukemia: clinical and therapeutic implications
L Kelly, J Clark, DG Gilliland - Curr. Opin. Oncol, 2002 - co-oncology.com
... In addition, the PAX5-paired box domain is retained in the fusion ... t(7;11)(p15;p15)
translocations giving rise to the BCR/ABL and NUP98/HOXA9 fusions associated ...
Cited by 11 - Web Search - siteman.wustl.edu - co-oncology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Ho me o box genes: a mole cu lar link betwe en deve lop ment and cancer Ge nes home o box: uma rela …
IDUCTI ON - Pesqui Odontol Bras, 2003 - scielo.br
... Fusi on of the nucle o po rin gene NUP98 to HOXA9 by the chromo so me translo ... Nutt
SL, Eberhard D, Horcher M. Pax5 deter mi nes the iden tity of B cells from ...
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E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... B progenitors, and infection with retrovirus encoding Hoxb8, Hoxa9, or Nup98-HoxA9
did not ... 2) nor the early B-cell differentiation genes Pax5, λ5, or VpreB ...
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Acute Leukemias New insights into MLL gene rearranged acute leukemias using gene expression …
A Kohlmann, C Schoch, M Dugas, S Schnittger, W … - Leukemia, 2005 - nature.com
... As given in Figure 3, HOXA9 as well as MEIS1 show up as genes with higher ... PAX5, the
B-cell-lineage-specific activator was designated as one of the top-ranked ...
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High incidence of proviral integrations in the Hoxa locus in a new model of E 2 a-PBX 1-induced B- … - Full text - MIT Libraries
J Bijl, M Sauvageau, A Thompson, G Sauvageau - Genes & Development, 2005 - genesdev.org
... 3A, right panels) and they expressed Pax5 (Supplementary Tables S2, S3), indicating ...
follows: Four were located in the intergenic region between Hoxa9 and Hoxa10 ...
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The roles of transcription factors in B lymphocyte commitment, development, and transformation
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Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... CR Kovac, MA Sepulveda, and BK Birshtein The Interaction of Pax5 (BSAP) with ... S.
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[PS] CITATIONS FOR PROTEIN/DNA (REGULATORY) - Full text - MIT Libraries
PDA White, X Ding, JC Vanderspek, JR Murphy, D … - J. Biol. Chem, 2004 - aist.go.jp
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t (8; 21) Breakpoints on Chromosome 21 in Acute Myeloid Leukemia are Clustered within a Limited … - Full text - MIT Libraries
H Miyoshi, K Shimizu, T Kozu, N Maseki, Y Kaneko, … - Proceedings of the National Academy of Sciences - pnas.org
... A. Mamo, E. Kroon, L. Jerome, J. Bijl, HJ Lawrence, K. Humphries, and G. Sauvageau
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Comparative genomics provides evidence for an ancient genome duplication event in sh
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Fusion of the TEL Gene on 12p13 to the AML1 Gene on 21q22 in Acute Lymphoblastic Leukemia - Full text - MIT Libraries
TR Golub, GF Barker, SK Bohlander, SW Hiebert, DC … - Proceedings of the National Academy of Sciences, 1995 - pnas.org
... Etten, J. Borrow, D. Housman, B. Druker, and DG Gilliland A murine model of CML
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The use of genetic microarray analysis to classify and predict prognosis in haematological … - Full text - MIT Libraries
AP Levene, GJ Morgan, FE Davies - Clinical and Laboratory Haematology, 2003 - blackwell-synergy.com
... Significantly, HOXA9 is deregulated by the t(7;11)(p15;p15) chromosomal translocation
in a ... B cell transcription factors including c-MYC, CIITA, Id3 PAX5 and Spi ...
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The pathophysiology of HOX genes and their role in cancer - Full text - MIT Libraries
DG Grier, A Thompson, A Kwasniewska, GJ McGonigle, … - J Pathol, 2005 - doi.wiley.com
... A nested pattern of Hoxa cluster genes was found, with Hoxa9 expressed in the
proximal part of the limbs, where the humerus or femur develops. ...
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Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT … - Full text - MIT Libraries
DE Zhang, P Zhang, ND Wang, CJ Hetherington, GJ … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... Home page, EMBO J. Home page B. Heavey, C. Charalambous, C. Cobaleda, and M. Busslinger
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Genomic approaches to the pathogenesis and treatment of acute lymphoblastic leukemias
SA Armstrong, JJD Hsieh, SJ Korsmeyer - Current Opinion in Hematology, 2002 - co-hematology.com
... et al.: Commitment to the B-lymphoid lineage depends on the transcription factor
Pax5. ... T, Feinstein E, Mor O, et al.: Upregulation of Meis1 and HoxA9 in acute ...
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Development of the Mammalian Female Reproductive Tract - Full text - MIT Libraries
Y Yin, L Ma - Journal of Biochemistry, 2005 - jb.oxfordjournals.org
... In the case of AbdB Hoxa genes, anterior limit of Hoxa9 expression was detected ... Meisler,
MH, and Busslinger, M. (1997) Cooperation of Pax2 and Pax5 in midbrain ...
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Control of Self-Renewal and Differentiation of Hematopoietic Stem Cells: HOXB4 on the Threshold - Full text - MIT Libraries
H KLUMP, B SCHIEDLMEIER, C BAUM - Ann. NY Acad. Sci, 2005 - annalsnyas.org
... organize hematopoiesis, for example AML1 (CBFA2), 14 PU.1, 15,16 Pax5, c-Myc ...
CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. ...
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Biology of hematopoietic stem cells - Full text - MIT Libraries
M Kondo, AJ Wagers, MG Manz, SS Prohaska, DC … - Annu. Rev. Immunol, 2003 - uiowa.edu
... HOXB4, as well as HOXA9, also enhances HSC ex- pansion in vivo when introduced via ...
of single CLPs coexpressed both B cell–specific (λ5 and/or Pax5) and T ...
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Gene Expression Profiling and Microarrays Gene expression profiling of leukemic cell lines reveals …
A Andersson, P Eden, D Lindgren, J Nilsson, C … - Leukemia, 2005 - nature.com
... The B-cell regulator PAX5 was upregulated in B-lineage ALL. ... Hoxa9 and Meis1 are
key targets for MLL-ENL-mediated cellular immortalization. ...
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Issues in Development
MAS MOORE - dx.doi.org
Page 1. STEM CELLS AND DEVELOPMENT 13:1–21 (2004) © Mary Ann Liebert, Inc. Issues
in Development Commentary The Role of Cell Migration in the Ontogeny of the ...
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HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription … - Full text - MIT Libraries
T Taghon, F Stolz, M De Smedt, M Cnockaert, B … - Blood, 2002 - bloodjournal.org
... 4. Thevenin C, Nutt SL, Busslinger M. Early function of Pax5 (BSAP) before the ... Mice
bearing a targeted interruption of the homeobox gene HOXA9 have defects in ...
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Cytogenetic and FISH Studies in Myelodysplasia, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia …
II Supplement - Genetic Testing - ishapd.org
... IgH PDGFRB, TEL IL3, IgH NPM, RARa DEK, CAN AF6, MLL IRF4, IgH HOXA9, NUP98 FGFR1,
ZNF198 c-MYC, IgH c-MYC, TCRad ETO, AML1 c-MYC, Ig1 AF9, MLL PAX5, IgH ABL ...
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Annual Review of Immunology - Full text - MIT Libraries
M Kondo, AJ Wagers, MG Manz, SS Prohaska, DC … - Annual Review of Immunology, 2003 - immunol.annualreviews.org
... HOXB4, as well as HOXA9, also enhances HSC expansion in vivo when introduced via ...
23% of single CLPs coexpressed both B cell-specific ( 5 and/or Pax5) and T cell ...
Web Search - phyto.annualreviews.org - phyto.annualreviews.org

The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... positively regulates granulocytic/monocytic differentiation, whereas its
down-regulation is necessary for progression of erythropoiesis HOXA9 important role ...
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Exploitation of stem cell plasticity - Full text - MIT Libraries
E Martin-Rendon, SM Watt - Transfusion Medicine, 2003 - blackwell-synergy.com
... Overexpression of HoxA9 in HSCs induces stem cell expansion (Thorsteinsdottir et
al., 2002), whereas HoxA5 and HoxA10 perturb their differentiation activity ...
Cited by 4 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Transcription factors, normal myeloid development, and leukemia - Full text - MIT Libraries
DG Tenen, R Hromas, JD Licht, DE Zhang - Blood, 1997 - bloodjournal.org
PDF Version of this Article. Citation Map. Email this article to a friend. Similar
articles found in: Blood Online PubMed. PubMed Citation. ...
Cited by 353 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Homeobox genes in normal and malignant cells - Full text - MIT Libraries
C Cillo, M Cantile, A Faiella, E Boncinelli - Journal of Cellular Physiology, 2001 - doi.wiley.com
... Lewis, 2000). Hoxa9, Hoxb9, and Hoxd9 regulate mammary gland development
during pregnancy (Chen and Capecchi, 1999). In contrast ...
Cited by 30 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Bibliography Current World Literature
MR Baer, LA Pixley, LA Ford… - Current Opinion in Oncology, 2002 - co-oncology.com
... Rozovskaia T, Feinstein E, Mor O, Foa R, Blechman J, Nakamura T, Croce CM, et al.:
Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 ...
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