A Peroxisome Proliferator-Activated Receptor-Alpha (PPARa) cDNA Cloned from Guinea-Pig Liver Encodes … - Full text - MIT Libraries
JD Tugwood, PR Holden, NH James, RA Prince, RA … - Arch. Toxicol, 1998 - springerlink.com
... for RNA loading. The rel- ative abundance of the PPARa transcripts was
esti- mated by scanning densitometry. After correcting for ...
Cited by 25 - Web Search - ncbi.nlm.nih.gov - csa.com

Design, synthesis, and evaluation of a new class of noncyclic 1, 3-dicarbonyl compounds as PPARa …
Z Li, C Liao, BCB Ko, S Shan, EHY Tong, Z Yin, D … - chipscreen.com
... left panel to right panel: compound 17 (purple) docked into the PPARa receptor co ...
12 h light/darkness cycle, a temperature of 21 °C, and a rel- ative humidity ...
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Peroxisome Proliferator-activated Receptors and their Relevance to Dermatology
P Friedmann, D Unit, LFS Block, S General - Acta Derm Venereol, 2005 - taylorandfrancis.metapress.com
... PPARa inhibits activation of NFkB via two mechanisms: first, PPARa interacts directly
with the Rel homology domain of the p65 subunit of NFkB (16, 44, 45). ...
Web Search - ingentaconnect.com

NF-kB: pivotal mediator or innocent bystander in atherogenesis - Full text - MIT Libraries
T Collins, MI Cybulsky - J Clin Invest, 2001 - pubmedcentral.nih.gov
... the nuclei of intimal smooth muscle cells contain both Rel proteins, suggesting
that ... PPARa stimulates b oxidation of fatty acids, while PPARg elicits adipocyte ...
Cited by 40 - Web Search

Role of redox-regulated transcription factors in inflammation, aging and age-related diseases
Y Lavrovsky, B Chatterjee, RA Clark, AK Roy - Exp Gerontol, 2000 - aging.pharm.pusan.ac.kr
... N-terminal region of approximately 300 amino acids termed the Rel homology domain ...
pro-inflammatory agent leukotriene B 4 (LTB 4 ) is a natural ligand for PPARa. ...
Cited by 49 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

Implementation of fatty acid carriers to skin irritation and the epidermal barrier - Full text - MIT Libraries
S NY - Contact Dermatitis, 2002 - ingentaconnect.com
... a clinical effect comparable to that of gluco- corticoids (3). Therefore, linoleic
acid may be rel- evant for modulated gene expression as a PPARa agonist. ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

Evidence That Peroxisome Proliferator–Activated Receptor Delta Influences Cholesterol Metabolism … - Full text - MIT Libraries
J Skogsberg, K Kannisto, TN Cassel, A Hamsten, P … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2003 - atvb.ahajournals.org
... against Sp-1 and nuclear factor (NF)- B; p50, p65, and c-Rel were used ... square test
was used to compare the observed numbers of PPARD and PPARA genotypes with ...
Cited by 4 - Web Search - intl-atvb.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 8 versions »

GEArray Q Series Human Cancer Drug Resistance & Metabolism Gene Array: AR-SAHS-019
FG Grouping - eurogentec.com
... Hormone Receptors: AR, ESR1 (ER-alpha), ESR2 (ER-beta-cx), PPARA, PPARD, PPARG ... MYC
(c-myc), NFKB1, NFKB2, NFKBIB (TRIP9), NFKBIE, RELB (l-rel), TNFRSF11A (Rank ...
View as HTML - Web Search - eurogentec.be

GEArray Q Series Mouse Cancer Drug Resistance & Metabolism Gene Array: AR-SAMM-019
FG Grouping - eurogentec.com
... Hormone Receptors: Ar, Esr1, Esr2, Igf2r, Ppara, Ppard, Pparg, Ppargc1, Rara, Rarb,
Rxra ... Mafb, Myc (c-myc), Nfkb1, Nfkb2, Nfkbib, Nfkbie, Relb (l-rel), Tnfrsf11A ...
View as HTML - Web Search - eurogentec.be

Stress-(and Diet-) Related Regulation of Hepatic Nuclear Receptors and Its Relevance for ABC- …
R Stienstra, E Lichtenauer-Kaligis, M Mueller - DRUG METABOLISM REVIEWS, 2004 - taylorandfrancis.metapress.com
... The PPARa-leukotriene B4 pathway to inflammation control. ... NF-kB and Rel proteins:
evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. ...
Web Search - nutrigene.4t.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Forum Review
RA DAYNES, E ENIOUTINA, DC JONES - ANTIOXIDANTS & REDOX SIGNALING, 2003 - dx.doi.org
... Restoration of PPARa, T-bet, interleukin-2, and IFNg responses was found in T ... least
five well characterized protein subunits (eg, p50, p52, p65, c-Rel, and RelB ...
Web Search - liebertonline.com - liebertonline.com - path.utah.edu

Causation of type 2 diabetes—the Gordian knot unravels - Full text - MIT Libraries
R Taylor - N Engl J Med, 2004 - fsm.ac.fj
... enzymes for the beta-oxidation of fatty acid, the rel- evance of an ... now known to
be agonists of peroxisome-prolif- erator–activated receptor a (PPARa)? ...
Cited by 15 - View as HTML - Web Search - courses.mcb.arizona.edu - dx.doi.org - content.nejm.org - all 7 versions »

Integrative Biological Analysis of the APOE* 3-Leiden Transgenic Mouse
CB Clish, E Davidov, M Oresic, TN Plasterer, G … - Omics A Journal of Integrative Biology, 2004 - dx.doi.org
... PC PPARa ... The shading inside the box indicates the rel- ative amount in the transgenic
animals compared to wild type controls (red 5 higher level; green 5 lower ...
Cited by 9 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Dual Role of Oxidized LDL on the NF-KappaB Signaling Pathway
F Robbesyn, R Salvayre, A Negre-Salvayre - Free Radical Research, 2004 - dx.doi.org
... [10–12] A characteristic feature of NF-kB proteins is that all the family members
share a highly conserved Rel homology domain ... [75 – 77] PPARa and PPARg ...
Cited by 3 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

INDUCTION OF THE HUMAN NEURONAL NITRIC OXIDE SYNTHASE EXPRESSION BY EPIDERMAL GROWTH FACTOR IS …
H Dihazi, J Kappler, V Gieselmann, F Dietz, A … - wissenschaft-online.de
... Mikhail Strokin Regulation of docosahexaenoic and arachidonic acid release in ... Recently,
we have shown that PPARa activators potentiate the expression of sPLA2 ...
View as HTML - Web Search - wissenschaft-online.de

Electrophoretic mobility-shift assay (EMSA) - Full text - MIT Libraries
M Humphreys - Proc. Natl Acad. Sci. USA, 1998 - nature.com
... was veri®ed by supershift with polyclonal antibodies speci®c for p65 (Rel A). ... Activation
of human aorta smooth-muscle cells is inhibited by PPARa but not by ...
Web Search

Expression and functional activity of PPARc in pancreatic b cells - Full text - MIT Libraries
HJ Welters, SC McBain, M Tadayyon, JHB Scarpello, … - British Journal of Pharmacology, 2004 - nature.com
... Rel a t i v e ex pre ssion lev ... curves were constructed from liver (a, b) and adipose
(c) and used to monitor the expression of PPAR isoforms (PPARa – panel a ...
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Novel Candidate Genes for Atherosclerosis Are Identified by Representational Difference Analysis- …
T Andersson, S Bor&auml ng, M Larsson, V Wirta, A … - Pathobiology, 2001 - content.karger.com
Page 1. Original Paper Pathobiology 2001;69:304–314 Novel Candidate Genes for
Atherosclerosis Are Identified by Representational Difference ...
Cited by 5 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Regulatory potential of n-3 fatty acids in immunological and inflammatory processes
H Grimm, K Mayer, P Mayser, E Eigenbrodt - Br J Nutr, 2002 - ingentaconnect.com
... cells, since they direct fatty acids away from storage towards oxidation by functioning
as ligand activators for PPARa and downregulate ... a and IL -6 rel ease ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Dietary Compounds in Relation to Dietary Diversity and Human Health
CL Hughes, TR Dhiman - Journal of Medicinal Food, 2002 - dx.doi.org
... within human popu- lations caused by dietary composition be rel- evant to ... CLA would
activate peroxisome prolifera- tor-activated receptors (PPARa, PPARb, or ...
Cited by 1 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor jB in …
K Kristiansen - ingentaconnect.com
... show that PPARd physically interacts with the N-term- inal Rel homology domain of
p65. ... The p65-dependent repression of PPARd- but not PPARa- or PPARc- mediated ...
Web Search

Unique renal tubule changes induced in rats and mice by the peroxisome proliferators 2, 4- …
K Ozaki, JF Mahler, JK Haseman, CR Moomaw, ML … - Toxicologic Pathology, 2001 - taylorandfrancis.metapress.com
... c pattern of expression is consistent with a role for PPARa , but not ... were also included
because, like humans, they are considered to be rel- atively resistant ...
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Unique Renal Tubule Changes Induced in Rats and Mice by the Peroxisome Proliferators 2, 4- …
K Ozaki, JF Mahler, JK Haseman, CR Moomaw, ML … - Toxicologic Pathology, 2001 - dx.doi.org
... c pattern of expression is consistent with a role for PPARa , but not ... were also included
because, like humans, they are considered to be rel- atively resistant ...
Web Search - ingentaconnect.com - csa.com

NF-kB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type - Full text - MIT Libraries
B Lin, C Williams-Skipp, Y Tao, MS Schleicher, LL … - Cell Death Differ, 1999 - nature.com
... terminal region of homology, termed the Rel homology domain, mediates dimerization,
DNA ... to play a role in apoptosis mediated by engagement of PPARa and PPARg ...
Cited by 51 - Web Search - nature.com - ncbi.nlm.nih.gov

Cyclopentenone Prostaglandins: New Insights on Biological Activities and CellularTargets
DS Straus, CK Glass - Key words, 2001 - doi.wiley.com
Page 1. Cyclopentenone Prostaglandins: New Insights on Biological Activities
and CellularTargets Daniel S. Straus, 1 Christopher K. Glass 2 ...
Cited by 105 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Marise Andreani, Jean-Luc Olivier 2 and Gilbert Bereziat
A Phospholipases - doi.wiley.com
Page 1. 2 Control of Eicosanoid Production by Cellular and Secreted Phospholipase
A 2 Marise Andreani 1 , Jean-Luc Olivier 2 and Gilbert Béréziat 1 ...
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Peroxisome Proliferator-activated Receptors in Atherosclerosis and Inflammation--An Update
CS Elangbam, RD Tyler, RM Lightfoot - Toxicologic Pathology, 2001 - dx.doi.org
... NF-j B is a mem- ber of the Rel family of proteins ... expression of peroxisome
proliferator-activated receptors (PPARs): Tissue distribution of PPARa , b , and ...
Cited by 15 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Phosphorylation of PPARg via Active ERK1/2 Leads to its Physical Association With p65 and Inhibition … - Full text - MIT Libraries
F Chen, M Wang, JP O’Connor, M He, T Tripathi, … - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... The expression of each PPAR isoform varies from tissue to tissue. PPARa is expressed
in hepatocytes, cardiomyocytes, and proximal tubule cells of the kidney. ...
Cited by 12 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Glutathione S-Transferase Polymorphisms and Their Biological Consequences
JD Hayes, RC Strange, JD Hayes, FTC Alert - Pharmacology, 2000 - content.karger.com
Page 1. Pharmacology 2000;61:154–166 Glutathione S-Transferase Polymorphisms and
Their Biological Consequences John D. Hayes a Richard C. Strange b ...
Cited by 94 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

New Approaches to Mechanism Analysis for Drug Discovery Using DNA Microarray Data Combined with …
H Sato, S Ishida, K Toda, R Matsuda, Y Hayashi, M … - Current Drug Discovery Technologies, 2005 - ingentaconnect.com
... protein kinase p38 PI3K = Phosphatidylinositol 3 kinase PPARa = Peroxisome proliferator ...
contribute to the oncogenicity of the retroviral oncoprotein v-Rel. ...
Web Search

REGULATION ET CROISSANCE: UN MODELE MONETAIRE-FINANCIER POUR UNE ECONOMIE OUVERTE
JG Loranger, G Boismenu - Forum de la regulation, Paris, 2001 - cpds.umontreal.ca
... m onnaie endog ène n'a ppara ît pas explicitemen t dan s le modèle. ... n 'existe plus
(vo ir l'équ ation f 2 du tableau 1). Le plein emploi structu rel E* ...
Cited by 1 - View as HTML - Web Search

Genes and human elite athletic performance - Full text - MIT Libraries
DG MacArthur, KN North - Human Genetics, 2005 - springerlink.com
... in the peroxisome prolif- erator-activated receptor a gene PPARA (Jamshidi et al ...
studies that obtained a positive association were generally rel- atively small ...
Web Search - ncbi.nlm.nih.gov

Role of Peroxisome Proliferator-Activated Receptor g Ligands in the Vessel Wall
A Jozkowicz, J Dulak, J Nanobashvili, M Prager, I … - springer.at
... Three types of PPAR have been described so far: PPARa, PPARd, and PPARg,
each encoded by a different gene (34). PPARa is expressed ...
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Resveratrol: Preventing properties against vascular alterations and ageing
D Delmas, B Jannin, N Latruffe - Molecular Nutrition & Food Research, 2005 - doi.wiley.com
Page 1. 377 i 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.mnf-journal.de
Mol. Nutr. Food Res. 2005, 49, 377–395 DOI 10.1002/mnfr.200400098 Review ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

EPIDEMIOLOGY
V Paracchini, P Pedotti, E Taioli - Am J Epidemiol, 2005 - cdc.gov
... There are three known subtypes of PPARs: PPARA, PPARD, and PPARG. ... compared with White
Americans, while the prevalence in Asian Americans is rel- atively low ...
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TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays (Column Separation Version) Cat. #
MA1210, MA1211, MA1212l, MA1213 & MA1214, MA1215 Product ...
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Education, occupational prestige, and income of Asian Americans
HR Barringer, DT Takeuchi, P Xenos - 1990 - psychology.ucdavis.edu
... Shanta Danara), whose care me theory, it is noteworthy that most of them ppara bluonA
-the data all fil=-.madc po _"_ anal to questioned some or all the ...
Cited by 25 - View as HTML - Web Search - Library Search

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... AAGTT not AAGT PPARA 01 PPAR/RXR heterodimers Core should be AAAGGT not
AAAG VMYB 02 v-Myb Core should be AACGG not AACG MYT1 01 ...
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The role of inflammation in atherothrombosis: current and future strategies of medical treatment - Full text - MIT Libraries
T Geisler, DL Bhatt - Med Sci Monit, 2004 - medscimonit.com
... The CURE trial showed a better outcome for pa- tients with acute coronary syndrome
treated with clopidog- rel plus aspirin on admission, although a higher ...
Cited by 1 - View as HTML - Web Search - medscimonit.com - ncbi.nlm.nih.gov

Research Article Carboxypeptidase E and thrombospondin-1 are differently expressed in subcutaneous …
JM Ramis, NLW Franssen-van Hal, E Kramer, I Llado, … - springerlink.com
... To perform the rel- ative standard curve, arbitrary template concentration values
(0.1, 0.01 and 0.001) were given to the three cDNA dilutions (mentioned above ...
Web Search

Molecular Classification of Renal Tumors by Gene Expression Profiling - Full text - MIT Libraries
AN Schuetz, Q Yin-Goen, MB Amin, CS Moreno, C … - Journal of Molecular Diagnostics, 2005 - jmd.amjpathol.org
... Rel- ative normalized gene expression was compared in renal tumor subtypes, with
statistical significance assessed by analysis of variance. ...
Web Search - jmd.amjpathol.org - ncbi.nlm.nih.gov

Plant Peroxisomes, Reactive Oxygen Metabolism and Nitric Oxide - Full text - MIT Libraries
A Luis, FJ Corpas, LM Sandalio, JM Palma, JB … - IUBMB Life, 2003 - dx.doi.org
... In the transgenic plants obtained, PPARa from frog (Xenopus laevis) was functional
and its expression in tobacco led to changes in general lipid metabolism and ...
Cited by 5 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov

Cell Death Pathways in Pancreatitis and Pancreatic Cancer
ASGSJ Pandol - Pancreatology, 2004 - content.karger.com
... NF-ÎB is a family of proteins sharing the Rel homology domain, which bind to DNA
as homo- or heterodimers resulting in activation of a multi- tude of stress ...
Web Search - content.karger.com - dx.doi.org

Inhibition of transforming growth factor beta 1-induced hepatoma cell apoptosis by liver tumor … - Full text - MIT Libraries
A Buchmann, C Willy, CL Buenemann, C Stroh, A … - Cell Death and Differentiation, 1999 - nature.com
Page 1. Inhibition of transforming growth factor beta1-induced hepatoma
cell apoptosis by liver tumor promoters: characterization ...
Cited by 19 - Web Search - nature.com - ncbi.nlm.nih.gov

Free Papers - Full text - MIT Libraries
CH WONG, CJ CHUA, CK LIAM, KL GOH, JINY KIM, SWOO … - Journal of Gastroenterology and Hepatology, 2004 - blackwell-synergy.com
Page 1. A296 Journal of Gastroenterology and Hepatology (2004) 19 (Suppl.)
Free Papers Conclusions The Id1 protein may play an important ...
Web Search - ingentaconnect.com

[BOOK] Bile Acids: From Genomics to Disease and Therapy
G Paumgartner, U Leuschner, D Keppler - 2003 - print.google.com
Page 1. Bile Acids: From Genomics to Disease and Therapy Page 2. • e ii iigu [uJ
vj•y4 Bile Acids: From Genomics to Disease and Therapy Edited by ...
Web Search - Get it from MIT Libraries - Library Search

Confounding Variables and Data Interpretation
KT Morgan, GA Boorman, HR Brown, Z Jayyosi, LM … - doi.wiley.com
... The transcriptome is highly dynamic, with many mRNA species having rel- atively
short half-lives, often less than 20 minutes, while interacting with an array ...
Web Search

PPAR gamma signaling exacerbates mammary gland tumor development - Full text - MIT Libraries
E Saez, J Rosenfeld, A Livolsi, P Olson, E … - Genes Dev, 2004 - genesdev.org
Institution: Google Indexer Sign In as Individual. GENES &
DEVELOPMENT 18:528-540, 2004 ISSN 0890-9369/ $5.00 ...
Cited by 17 - Web Search - belmonte.salk.edu - pubmedcentral.nih.gov - dx.doi.org - all 10 versions »

A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing … - Full text - MIT Libraries
CN Serhan - Histochemistry and Cell Biology, 2004 - springerlink.com
... In hepatocytes, ATL signifi- cantly reduces PPARa and cytokine-induced neutrophil
chemoattractant (CINC)-1 (Planagumà et al. 2002). With ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human … - Full text - MIT Libraries
M Heim, O Frank, G Kampmann, N Sochocky, T … - Endocrinology, 2004 - dfbs.ch
... Expression levels less than 1.0E-07 rel- ative to 18S rRNA were marginally low and
therefore considered not to be present by definition. Heim et al. ...
Cited by 5 - View as HTML - Web Search - dfbs.ch - endo.endojournals.org - ncbi.nlm.nih.gov - all 5 versions »