Subnucleaere Lokalisation des Transkriptionsfaktors STAT3 - Full text - MIT Libraries
A Herrmann - J. Cell Sci - sylvester.bth.rwth-aachen.de
I Subnucleäre Lokalisation des Transkriptionsfaktors STAT3 ... 6 1.2.3.
Aktivierung und nucleäre Translokation von STAT3..... ...
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Posttranslational modification of TEL and TEL/AML1 by SUMO-1 and cell-cycle-dependent assembly into … - Full text - MIT Libraries
SR Chakrabarti, R Sood, S Nandi, G Nucifora - Blood, 2004 - dx.doi.org
... A. Kuster, S. Haan, W. Becker, PC Heinrich, and G. Muller-Newen STAT3 is enriched ...
V. Senyuk, S. Sitailo, Y. Chi, and G. Nucifora Interaction of EVI1 with cAMP ...
Cited by 52 - Web Search - pnas.org - pubmedcentral.nih.gov - ijp-online.com - all 8 versions »

Transcriptional regulation during myelopoiesis
N Lenny, JJ Westendorf, SW Hiebert - Mol Biol Rep, 1997 - springerlink.com
... of AML-1 fused to several alternate transcripts, including the Evi1 transcription
regulator [43 ... Both STAT1 and STAT3 are activated by GM-CSF [124], and STAT3 is ...
Cited by 41 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

RB and hbrm cooperate to repress the activation functions of E2F1 - Full text - MIT Libraries
D Trouche, C Le Chalony, C Muchardt, M Yaniv, T … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... Home page B. Barre, A. Vigneron, and O. Coqueret The STAT3 Transcription Factor
Is a ... page Y. Chi, V. Senyuk, S. Chakraborty, and G. Nucifora EVI1 Promotes Cell ...
Cited by 126 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

The role of the AML1 transcription factor in leukemogenesis
RB Lorsbach, JR Downing - Int J Hematol, 2001 - cardenjennings.metapress.com
... well, including the t(16;21) [AML1-MTG16],t(3;21) [AML1-EVI1],and t ... structurally
related DNA-binding proteins including p53, NF- B, NFAT, STAT1, and STAT3 [10,11 ...
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Fusion of the ets Transcription Factor TEL to Jak2 Results in Constitutive Jak-Stat Signaling - Full text - MIT Libraries
MYH Jen, BK Beattie, JA Squire, DA Frank, DL … - Blood, 1999 - bloodjournal.org
... 56 Therefore, TEL-Jak2 JH1 could potentially directly recruit and activate Stat1,
Stat3, and Stat5. ... resulting in the fusion of one allele of TEL to EVI1 65 and ...
Cited by 43 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

A comparative analysis of relative occurrence of transcription factor binding sites in vertebrate … - Full text - MIT Libraries
M Stepanova, T Tiazhelova, M Skoblov, A Baranova - Bioinformatics, 2005 - bioinformatics.oxfordjournals.org
... This is also indicative of positive selection for EVI1 TFBS in the mouse lineage.
On the other hand, binding sites for factors STAT1, STAT3 and V-JUN were ...
Web Search - bioinformatics.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Novel variant isoform of G-CSF receptor involved in induction of proliferation of FDCP-2 cells: … - Full text - MIT Libraries
N Awaya, H Uchida, Y Miyakawa, K Kinjo, H … - Journal of Cellular Physiology, 2002 - doi.wiley.com
... Moreover, these isoforms showed prolonged activation of STAT3 in response to G-CSF
than did the wild-type. ... The blot was reprobed with anti-STAT3 antibody. ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34 cells, allowing nerve growth …
JC Mulloy, V Jankovic, M Wunderlich, R Delwel, J … - pnas.org
... the formation of the AML1-ETO (RUNX1-CBFA2T1) [t(8;21)], RUNX1/MDS/EVI1 [t(3 ... prepared
and analyzed by Western blot for the level of ERK, AKT, STAT3, and STAT5 ...
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TEL-JAK2 Mediates Constitutive Activation of the Phosphatidylinositol 3'-Kinase/Protein Kinase B … - Full text - MIT Libraries
HHN Melody, MYH Jenny, BK Beattie, DL Barber - J. Biol. Chem, 2001 - jbc.org
... (TEL-JAK2 (5-12)) (9) and the other TEL allele was fused to EVI1 (11). All
three fusions have ... STAT3 (15), STAT5 (13-16) and STAT6 (15). ...
Cited by 11 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... IRF2 01 Interferon regulatory factor 2 Core should be AAGYGAAA not GAAA EVI1 06
Ectopic viral integration site 1 encoded factor Core should be ACAAGAT not AGAT ...
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An Overview of Translocation-Related Oncogenesis in the Chronic Myeloid Leukaemias
BJ Bain - Acta Haematologica, 2002 - content.karger.com
... ABL into a cell line has been shown to result in activation of STAT1, STAT3 and
STAT5 ... with t(3;12)(q26;p13) who was found to have an ETV6-MDS/EVI1 fusion gene ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Chromosomal Translocations in Hematologic Malignancies
CG Brunstein, SJ Dylla, CM Verfaillie - Current Genomics, 2002 - ingentaconnect.com
Page 1. Current Genomics, 2002, 3, 313-334 313 1389-2029/02 $35.00+.00 © 2002
Bentham Science Publishers Ltd. Chromosomal Translocations ...
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Leukemogenesis by CBF oncoproteins
AD Friedman - Leukemia, 1999 - nature.com
... t(3;21)(q26;q22) is an uncommon translocation associated with myelodysplastic syndrome,
therapy-associated AML, or CML blast-crisis and encodes AML1-MDS1/EVI1. ...
Cited by 45 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Role of Cyclic-AMP Binding Protein(CREB) in Leukemia Cell Proliferation and Acute Leukemias
D SHANKAR, K SAKAMOTO - Leukemia & Lymphoma, 2004 - dx.doi.org
... (STAT3) activation, which regulates differentiation and survival, while SHP-2, Grb2,
and Shc ... G. and Ren, R. (2000) ‘‘Human AML1/ MDS/EVI1 fusion protein ...
Cited by 1 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Estrogen-regulated Conditional Oncoproteins: Tools to Address Open Questions in Normal Myeloid Cell …
DB Sykes, MP Kamps - Leukemia & Lymphoma, 2003 - dx.doi.org
... N. and Perkins, AS (1996) “Retroviral insertional activation of the EVI1 oncogene
does ... T., Hibi, M. and Hirano, T. (1996) “A central role for Stat3 in IL-6 ...
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G ENETIC P ROFILE OF A CUTE M YELOID L EUKEMIA - Full text - MIT Libraries
C Mecucci, R Rosati, R La Starza - Reviews in Clinical & Experimental Hematology, 2002 - blackwell-synergy.com
... gene is involved at 3q21 as in the inv(3). Both EVI1 and MEL1 ... survival and proliferation
of c-kit mutant leukemic clones, such as STAT3 and phosphatidylinositol ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Cloning and Characterization of the Novel Chimeric Gene TEL/PTPRR in Acute Myelogenous Leukemia with … - Full text - MIT Libraries
F Nakamura, Y Nakamura, K Maki, Y Sato, K Mitani - Cancer Research, 2005 - cancerres.aacrjournals.org
... After cytokine depletion, phosphorylated signal transducers and activators of
transcription 3 (STAT3) significantly declined in mock cells, but remained in ...
Web Search - cancerres.aacrjournals.org

Analysis of the interaction of TIP60β and PIN1 with the ets family transcription factor ETV6
CD Zhang - edoc.ub.uni-muenchen.de
... SYK, and FGFR3, to transcription factors, such as AML1/RUNX1, EVI1, ... et al., 2003).
TIP60 interacts with STAT3 and represses STAT3-mediated gene expression. ...
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AML1 interconnected pathways of leukemogenesis
J Michaud, HS Scott, R Escher - Cancer Invest, 2003 - taylorandfrancis.metapress.com
... Transcription activators STAT3 d Signal transducer and acti- vator of transcription
3 Not specific In silico [223] Constitutive expression [57] ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... MYH11 379 P. Paul Liu, Lucio H. Castilla, and Neeraj Adya 22 EVI1
Rearrangements in Malignant Hematopoiesis 393 Giuseppina Nucifora ...
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Signaling of transforming growth factor-b family members through Smad proteins
S Itoh, F Itoh, MJA Goumans, P ten Dijke - cancer - ingentaconnect.com
... 86±88], as well as negative, eg by binding proto- oncogene products Evi1 [120],
Ski ... STAT3, which is activated by LIF, was found to interact indirectly with BMP ...
Cited by 41 - Web Search

Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas …
WO Lui, T Foukakis, J Liden, SR Thoppe, T Dwight, … - Oncogene, 2004 - nature.com
... V1 subunit A (ATP6V1A1) and signal transducer and activator of transcription 3
(STAT3) (data not ... showed that the t(3;21) fusion product (ie AML1-EVI1) found in ...
Cited by 1 - Web Search - nature.com - bea.ki.se - ncbi.nlm.nih.gov - Get it from MIT Libraries

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal … - Full text - MIT Libraries
J Schwaller, J Frantsve, J Aster, IR Williams, MH … - The EMBO Journal, 1998 - embojournal.npgjournals.com
... ABL in t(9;12) (q34;p13) in rare cases of childhood ALLs (Papadopolous et al., 1995);
MN1 in t(12;22) (p13;q11) in AML (Buijs et al., 1995 ); and MDS/EVI1 in t ...
Cited by 107 - Web Search - nature.com - med.kuleuven.ac.be - ncbi.nlm.nih.gov - all 8 versions »

NEW EMBO MEMBER’S REVIEW - Full text - MIT Libraries
J Massague, D Wotton - The EMBO Journal, 2000 - embojournal.npgjournals.com
... astrocyte formation is mediated by a complex between Smad1 and Stat3 bridged by ... The
zinc-finger transcriptional repressor protein Evi1, which also exists as a ...
Cited by 4 - Web Search - emboj.org - pubmedcentral.nih.gov

NEW EMBO MEMBER'S REVIEW Transcriptional control by the TGF-b/Smad signaling system - Full text - MIT Libraries
J MassagueA, D Wotton - The EMBO Journal, 2000 - emboj.org
... astrocyte formation is mediated by a complex between Smad1 and Stat3 bridged by ... The
zinc-®nger transcriptional repressor protein Evi1, which also exists as a ...
Cited by 107 - Web Search - nature.com

AML1-MTG8 leukemic protein induces the expression of granulocyte colony-stimulating factor (G-CSF) … - Full text - MIT Libraries
K Shimizu, I Kitabayashi, N Kamada, T Abe, N … - Blood, 2000 - bloodjournal.org
... transcription factors such as AML1-MTG8/ETO, TEL-AML1, AML1-EVI1, AML1-MTG16 ... for
the transmission of growth signals 21 , 22 via JAK2 activation, STAT3 and STAT5 ...
Cited by 22 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

On the Power of Profiles for Transcription Factor Binding Site Detection
S Rahmann, T Mueller, M Vingron - Statistical Applications in Genetics and Molecular Biology, 2003 - genereg.molgen.mpg.de
Page 1. On the Power of Profiles for Transcription Factor Binding Site Detection
Sven Rahmann 1,2,∗ , Tobias Muller 1,3 , and Martin Vingron 1 ...
Cited by 11 - View as HTML - Web Search - molgen.mpg.de - gi.cebitec.uni-bielefeld.de

Signaling of transforming growth factor-beta family members through Smad proteins - Full text - MIT Libraries
S Itoh, F Itoh, MJ Goumans, P ten Dijke - European Journal of Biochemistry, 2000 - content.febsjournal.org
... 86-88], as well as negative, eg by binding proto-oncogene products Evi1 [120], Ski ...
STAT3, which is activated by LIF, was found to interact indirectly with BMP ...
Cited by 95 - Cached - Web Search - ejbiochem.org - blackwell-synergy.com - ncbi.nlm.nih.gov - all 6 versions »

Statistical Applications in Genetics and Molecular Biology
FBS Detection - bepress.com
Page 1. Statistical Applications in Genetics and Molecular Biology Volume 2, Issue
1 2003 Article 7 On the Power of Profiles for Transcription ...
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TGF-induced SMAD2 phosphorylation predicts inhibition of thymidine incorporation in CD34 cells from …
S Koschmieder, WK Hofmann, J Kunert, S Wagner, K … - Leukemia, 2001 - nature.com
Page 1. Leukemia (2001) 15, 942–949 © 2001 Nature Publishing Group All
rights reserved 0887-6924/01 $15.00 www.nature.com/leu ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene … - Full text - MIT Libraries
SJ Erkeland, M Valkhof, C Heijmans-Antonissen, R … - Blood, 2003 - bloodjournal.org
... Phenotyping of Evi1, Evi11/Cb2, and Evi12 transformed leukemias isolated from a ...
STAT3-mediated differentiation and survival and of myeloid cells in response to ...
Cited by 9 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Divergence and convergence of TGF-b/BMP signaling - Full text - MIT Libraries
K Miyazono, K Kusanagi, H Inoue - J. Cell Physiol, 2001 - doi.wiley.com
... is known about transcription factors that interact with BR-Smads (Miyazono, 2001)
but it has been shown that BR-Smads indirectly interact with STAT3 through a ...
Cited by 135 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Production of high-titer helper-free retroviruses by transient transfection - Full text - MIT Libraries
WS PEAR, GP NOLAN, ML SCOTT, D BALTIMORE - Proc. Nat. Acad. Sci, 1993 - pnas.org
... Home page, Blood Home page I. Nishikata, H. Sasaki, M. Iga, Y. Tateno, S. Imayoshi,
N. Asou, T. Nakamura, and K. Morishita A novel EVI1 gene family, MEL1 ...
Cited by 1223 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 5 versions »

Molecular regulation of cytokine gene expression during the immune response
JP Viola, A Rao - J Clin Immunol, 1999 - springerlink.com
... Homozygous disruption of the STAT3 gene resulted in an embryonic lethal phenotype
that attests to the pleiotropic role of cytokines in early development (37). ...
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Dokumentation und Evaluation der Weiterbildung Abstracts
S mit Nabelschnurblut, E Session, SC … - Onkologie, 2004 - content.karger.com
Page 1. 8 Stammzelltransplantation mit Nabelschnurblut Ch. Urban Klinische Abteilung
für Pädiatrische Hämatologie/Onkologie Universitätsklinik ...
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The Common Viral Insertion Site Evi12 Is Located in the 5'-Noncoding Region of Gnn, a Novel Gene … - Full text - MIT Libraries
E van den Akker, Y Vankan-Berkhoudt, PJM Valk, B … - J Virol, 2005 - jvi.asm.org
... Phenotyping of Evi1, Evi11/Cb2, and Evi12 transformed leukemias isolated from a
novel ... SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact ...
Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Bibliography Current World Literature
MR Baer, LA Pixley, LA Ford… - Current Opinion in Oncology, 2002 - co-oncology.com
... MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and ... Schuringa JJ,
Wierenga ATJ, Kruijer W, Vellenga E: Constitutive Stat3, Tyr705, and Ser727 ...
Web Search - co-rheumatology.com - co-gastroenterology.com - co-endocrinology.com - all 9 versions »

S tem C ells
UMESC Lines - stemcells.nih.gov
... The nanog gene is capable of maintaining mouse ES cell self-renewal independent
of the LIF/Stat3 pathway associated with transcription factors such as Oct-4 ...
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Current World Literature; Bibliography
T Blake, N Adya, CH Kim… - Current Opinion in Hematology, 2001 - co-hematology.com
July 2001, 8:4 > Current World Literature;Bibliography... < Previous |
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Differentielle Genexpressionsanalyse von Smad4 defizienten Pankreaskarzinomzelllinien nach …
DBM Zapatka - www-brs.ub.ruhr-uni-bochum.de
... zum Beispiel AP-1, die SP-1- und AML-Familie) oder negativem Einfluss (zum
Beispiel Evi1 und E1A) auf TGFβ Zielgene wurden beschrieben ...
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Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts
C Sillaber, M Mayerhofer, H Agis, V Sagaster, C … - Wien Klin Wochenschr, 2003 - springer.at
Page 1. 485 Sillaber et al., Chronic myeloid leukemia Wien Klin Wochenschr
(2003) 115/13–14: 485–504 © Springer-Verlag 2003 ...
Cited by 4 - View as HTML - Web Search - biologicalprocedures.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

cis-Regulatory Control of Cell Fate-Specific Genes in Caenorhabditis elegans Vulval Organogenesis
M Kirouac, PW Sternberg - etd.caltech.edu
Page 1. cis-Regulatory Control of Cell Fate-Specific Genes in Caenorhabditis elegans
Vulval Organogenesis Martha Kirouac and Paul W. Sternberg ...
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Bibliography Current World Literature
JY Bertrand, S Giroux, R Golub… - Current Opinion in Hematology, 2005 - co-hematology.com
May 2005, 12:3 > Bibliography Current World Literature. ...
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TGFβ and its Smad Connection to Cancer
S Thiagalingam, K Cheng, RL Foy, HJ Lee, D … - Current Genomics, 2002 - ingentaconnect.com
... Similarly, DNA binding factors such as SIP1 and TGIF or non-DNA binding factors
such as Evi1, Ski and SnoN could interact with the Smad proteins in the ...
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Bibliography Current World Literature
CD Bloomfield, KJ Archer, K Mrozek, DM Lillington, … - Current Opinion in Oncology, 2003 - co-oncology.com
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cis-Regulatory control of three cell fate-specific genes in vulval organogenesis of C. elegans and C … - Full text - MIT Libraries
M Kirouac, PW Sternberg - Dev Biol, 2003 - etd.caltech.edu
Page 1. cis-Regulatory Control of Three Cell Fate-Specific Genes in Vulval
Organogenesis of C. elegans and C. briggsae Thesis by Martha Kirouac ...
Cited by 16 - View as HTML - Web Search - etd.caltech.edu - ncbi.nlm.nih.gov