Dean’s Lecture - Full text - MIT Libraries
MS Regulating, C Cells - The Mount Sinai Journal OF Medicine, 2004 - mssm.edu
... Key Words: Anoikis, PI3 kinase, Stat3, Rho GTPases, anchorage. ... triphosphatase
IGF-1: insulin-like growth factor-1 IGFR: IGF-1 receptor ILK: integrin-linked ...
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A10 Receptors or intracellular mediators involved in non-lipid-derived signalling pathways
RM Nuesing, C Wagner, A Kurtz, S Narumiya, M Choi, … - ndt.oupjournals.org
... Our laboratory have previously reported that STAT3 maybe involved in thrombin-induced
expression of the Timp-1gene in cultured human mesan- gial cells. ...
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IDENTIFICATION OF A CELL SENESCENCE GENE AT 6Q16. 3 IN BREAST CANCER CELLS Raghbir S. Athwal, Neena …
VK Zhawar, GP Kaur - mrmc-rad6.army.mil
... (2) STAT3 activation (phosphorylation ... Here, we present evidence that the
Integrin-Linked Kinase (ILK) gene maps to the commonly deleted chromosome 11p15. ...
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Targeting the Epidermal Growth Factor Receptor in Cancer - Full text - MIT Libraries
CE Biomarkers, PMC Therapeutics - Cancer Research, 2003 - cancerres.aacrjournals.org
... YW, Wang LM, Jove R., Vande Woude GF Requirement of Stat3 signaling for ... Attwell S.,
Roskelley C., Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis ...
Web Search - cancerres.aacrjournals.org

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... BTK, C20orf97, CTMP, GNB1, GRB2, GRB10, HSPB1, HSPCA, HSPCB, ILK, IMPDH1, INPP5D ...
JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A ...
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Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, … - Full text - MIT Libraries
JA Recio, G Merlino - Oncogene, 2002 - nature.com
... SH2-containing proteins such as PI3K, phospholipase Cg (PLC-g), Stat3, Src, Grb2 ...
1), platelet-derived growth factor (PDGF), integrin-linked kinase (ILK) and HGF ...
Cited by 23 - Web Search - nature.com - ncbi.nlm.nih.gov

Homeostatic control of lymphocyte survival: potential origins and implications - Full text - MIT Libraries
DR Plas, JC Rathmell, CB Thompson - Nature Immunology, 2002 - nature.com
... Activation of both STAT1 and STAT3, as well as the PI3K-Akt pathway have ... kinase
(FAK), and serine-threonine kinases, such as integrin-linked kinase (ILK) 54 . ...
Cited by 33 - Web Search - nature.com - ncbi.nlm.nih.gov

Dexamethasone Increased Plasminogen Activator Inhibitor-1 Expression on Human Umbilical Vein …
YYAIH Ikeda, N Otsuka, T Yoshiki - Pathobiology, 2004 - content.karger.com
... IÎB-ß L40407 5.1 YY1 Z14077 6.9 NF-E2-like 1 X77366 4.5 STAT3 L29277 5.0 ... Protein
kinases bcr X02596 9.1 IRAK-1 L76191 27.4 raf-A X04790 5.8 ILK U40282 5.0 ...
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Proteomics Approaches to Identify Phosphorylation Modifications Induced by Galectin-1 in Jurkat T- …
A Binding, MLC Lines - mcponline.org
... Nocodazole treatment also induced phosphorylation of Stat3 Ser-727, which is rapamycin ...
Integrin-linked kinase (ILK), a cytoplasmic beta1 and beta3 integrin bind ...
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Minireview: Cyclin D1: Normal and Abnormal Functions - Full text - MIT Libraries
M Fu, C Wang, Z Li, T Sakamaki, RG Pestell - Endocrinology, 2004 - endo.endojournals.org
... with its essential cofactors such as CBP/p300; alternatively, STAT3 nuclear
localization ... cyclin D1 via focal adhesion kinase and integrin-linked kinase (ILK). ...
Cited by 8 - Web Search - endo.endojournals.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer - Full text - MIT Libraries
MN Younes, S Kim, OG Yigitbasi, M Mandal, SA … - Mol Cancer Ther, 2005 - mct.aacrjournals.org
... Regulation of tumor angiogenesis by integrin-linked kinase (ILK). ... by a selective
small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR ...
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AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is … - Full text - MIT Libraries
M Sun, G Wang, JE Paciga, RI Feldman, ZQ Yuan, XL … - Am J Pathol, 2001 - ajp.amjpathol.org
... of Thr-308 and Ser-473 by PDK1 and PDK2/ILK, respectively ... Activation of oncogenic
signaling proteins, such as Stat3, mitogen-activated protein kinase, and p110 ...
Cited by 84 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov

GSK 3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 … - Full text - MIT Libraries
JJ Grzesiak, KC Smith, DW Burton, LJ Deftos, M … - International Journal of Cancer, 2005 - doi.wiley.com
... serum; Fn, fibronectin; GSK3, glycogen synthase kinase 3; IL, interleukin; ILK,
integrin-linked ... Notably, STAT3, MEK1/2, CREB, ERK1 and ERK2 were all heavily ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Differential regulation of cell motility and invasion by FAK - Full text - MIT Libraries
DA Hsia, SK Mitra, CR Hauck, DN Streblow, JA … - J. Cell Biol, 2003 - intl.jcb.org
... 2 A). Both v-Src and ILK were similarly distributed within ... A). Anti-phosphotyrosine
(pTyr) blotting and phospho-specific antibodies to STAT3 (pSTAT3) revealed ...
Cited by 50 - Web Search - dx.doi.org - intl.jcb.org - ncbi.nlm.nih.gov - all 5 versions »

Anoikis: roadblock to cell transplantation
I Zvibel, F Smets, H Soriano - Cell Transplant, 2002 - ingentaconnect.com
... S.; Roskelley, C.; Dedhar, S. The integrin-linked kinase (ILK) suppresses anoikis. ...
and antiapoptotic ac- tions of hepatocyte growth factor through ERK, STAT3, ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase - Full text - MIT Libraries
MP Myers, JP Stolarov, C Eng, J Li, SI Wang, MH … - Proc Natl Acad Sci USA, 1997 - dx.doi.org
... Home page, J Gen Virol Home page S. Sun and BM Steinberg PTEN is a negative regulator
of STAT3 activation in human papillomavirus-infected cells J. Gen. ...
Cited by 275 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3, 4, 5,- … - Full text - MIT Libraries
H Sun, R Lesche, DM Li, J Liliental, H Zhang, J … - Cell, 1999 - dx.doi.org
... CS Zong, S. Uttamsingh, P. Sachdev, M. Bhanot, MT Le, JLK Chan, and LH Wang The
Role of Phosphatidylinositol 3-Kinase, Rho Family GTPases, and STAT3 in Ros ...
Cited by 183 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Cellular Physiology and Biochemistry
C Hydration, I Signalling - Cell Physiol Biochem, 2000 - content.karger.com
... integrin-linked kinase (ILK) [42] which are components of the focal adhesion signalling ...
30 min in a significant stimulation of STAT1 and STAT3 DNA binding [46 ...
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Short Communication - Full text - MIT Libraries
M Sun, G Wang, JE Paciga, RI Feldman, ZQ Yuan, XL … - American Journal of Pathology, 2001 - ajp.amjpathol.org
... of Thr-308 and Ser-473 by PDK1 and PDK2/ILK, respectively ... Activation of oncogenic
signaling proteins, such as Stat3, mitogen-activated protein kinase, and p110 ...
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Validating siRNAs for Signal Transduction Research
NRM Antibodies - ozyme.fr
... Several kinases, including ILK-1, PDK1, Akt itself, and perhaps other AGC kinases,
have the potential to phosphorylate Akt at this site (4). Phosphorylated Akt ...
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[CITATION] Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis … - Full text - MIT Libraries
AP Putzke, ST Hikita, DO Clegg, JH Rothman - Development, 2005
Page 1. 3185 Introduction The complex forms of animals are sculpted from
amorphous collections of cells by alterations in cell shape ...
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[CITATION] Signal Transduction Virtual Journal - Full text - MIT Libraries
AP Putzke, ST Hikita, DO Clegg, JH Rothman - Development
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Role of Akt signaling in vascular homeostasis and angiogenesis - Full text - MIT Libraries
I Shiojima, K Walsh - Circ Res, 2002 - circres.ahajournals.org
... integrin signaling molecules including focal adhesion kinase (FAK), ILK, and Shc ...
antiapoptotic actions of hepatocyte growth factor through ERK, Stat3, and Akt ...
Cited by 75 - Web Search - intl-circres.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 7 versions »

Order and disorder: the role of extracellular matrix in epithelial cancer
D Radisky, J Muschler, MJ Bissell - Cancer Invest, 2002 - taylorandfrancis.metapress.com
... These include tyrosine kinases such as focal adhesion kinase (FAK), integrin-linked
kinase (ILK), and members of the Src kinase family, as well as serine ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis
RK Sironen, HM Karjalainen, K Toerroenen, MA Elo, … - Biorheology, 2002 - iospress.metapress.com
... 0.5 0.9 2.0 growth factor D16431 signal transducer and activator of transcription
3 (STAT3) ... integrin-linked kinase (ILK) 0.2 0.9 2.1 signal transduction U40282 ...
Cited by 2 - Web Search - uku.fi - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma …
SJ Rogers, C Box, KJ Harrington, C Nutting, P Rhys … - Expert Opin. Ther. Targets, 2005 - ashley-pub.com
... for mediating cellular responses to growth factors or cytokine stimulation [17-19]
integrin ligation and signalling via integrin-linked kinase (ILK) [20] or ...
Web Search - ashley-pub.com

Androgen Receptor Signaling in Androgen-Refractory Prostate Cancer - Full text - MIT Libraries
N Prostate - Journal of the National Cancer Institute, 2001 - jncicancerspectrum.oupjournals.org
... IL-6 can also activate signal transducer and activators of tran- scription
(STATs), such as STAT3, through the Janus kinase pathway. ...
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Signal Transduction BY Cell Adhesion Receptors AND THE Cytoskeleton: - Full text - MIT Libraries
RL Juliano - Annu. Rev. Pharmacol. Toxicol, 2002 - pharmtox.annualreviews.org
Page 1. Annu. Rev. Pharmacol. Toxicol. 2002. 42:283–323 Copyright c 2002 by Annual
Reviews. All rights reserved S IGNAL T RANSDUCTION BY C ELL A DHESION ...
Cited by 103 - Web Search - phyto.annualreviews.org - med.unc.edu - ncbi.nlm.nih.gov - all 5 versions »

Full Text View - Full text - MIT Libraries
R DACKOUR, T CARTER, BM STEINBERG - In Vitro Cellular & Developmental Biology-Animal - bioone.org
... However, reducing levels of either ILK or PDK1 did not inhibit K13 expression ... PTEN
is a negative regulator of STAT3 activation in human papillomavirus-infected ...
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Cholesterol and prostate cancer - Full text - MIT Libraries
MR Freeman, KR Solomon - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
Page 1. Journal of Cellular Biochemistry 91:54–69 (2004) Cholesterol and Prostate
Cancer Michael R. Freeman 1,2 * and Keith R. Solomon ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Epithelial-Mesenchymal Transformation during Craniofacial Development - Full text - MIT Libraries
P Kang, KKH Svoboda - J Dent Res, 2005 - jdr.iadrjournals.org
... 1,1-dioctadecyl-3,3,3'-tetramethylindocarbocyanine perchlorate; EMT, epithelial-
mesenchymal transformation; FGF, fibroblast growth factor; ILK, integrin-linked ...
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[BOOK] Protein kinase functions
JR Woodgett - 2000 - print.google.com
... 410. Ilk TITLES IN THE SERI ES 1. Human Retroviruses fln,an R. Cull:':: 2. Steroid
Hormone Action Ala! ... 206 3.6 Stat2 208 3.7 Stat3 209 3.8 Stat4 21 1 3.9 Stat6 ...
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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the … - Full text - MIT Libraries
LC Cantley, BG Neel - Am. J. Pathol, 2004 - dx.doi.org
Full Text of this Article. PDF Version of this Article. Similar articles found
in: PNAS Online ISI Web of Science PubMed. PubMed Citation. ...
Cited by 494 - Web Search - pnas.org - pubmedcentral.nih.gov - wfu.edu - all 7 versions »

Annual Review of Pharmacology and Toxicology - Full text - MIT Libraries
RL Juliano - Annual Review of Pharmacology and Toxicology, 2002 - pharmtox.annualreviews.org
... ILK, an integrin-associated kinase, can also inhibit GSK-3 , thus linking the Wnt/
-catenin pathway to integrins. Cadherins also signal via other pathways. ...
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Analysis of the Protein Kinase B–Forkhead box O signaling pathway
APJ van den Heuvel - igitur-archive.library.uu.nl
Page 1. Analysis of the Protein Kinase B – Forkhead box O signaling pathway Analyse
van de proteine kinase B – Forkhead box O signaleringsroute ...
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Paxillin: Adapting to Change - Full text - MIT Libraries
MC Brown, CE Turner - Physiol Rev, 2004 - physrev.physiology.org
... 3). Within paxillin, LD1 mediates interactions with actopaxin (183), the
integrin-linked kinase (ILK) (184), vinculin (278), and the papillomavirus protein ...
Cited by 2 - Web Search - physrev.physiology.org - ncbi.nlm.nih.gov

Targeted therapy for epithelial ovarian cancer: Current status and future prospects
HT SEE, JJ KAVANAGH, W HU, RC BAST JR - Cancer, 2003 - ingentaconnect.com
Page 1. REVIEW ARTICLE Targeted therapy for epithelial ovarian cancer: Current status
and future prospects HT SEE, JJ KAVANAGH, W. HU & RC BAST, JR. ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Phosphotyrosine Signaling Networks in Epidermal Growth Factor Receptor Overexpressing Squamous … - Full text - MIT Libraries
A Thelemann, F Petti, G Griffin, K Iwata, T Hunt, … - Molecular & Cellular Proteomics, 2005 - mcponline.org
... Erk1/2, PI-3 kinase and STAT3/5. Focal adhesion proteins, FAK, Pyk2, paxillin,
ARF/GIT1, plakophillin were downregulated by transient ...
Cited by 3 - Web Search - mcponline.highwire.org - mcponline.org - ncbi.nlm.nih.gov - all 7 versions »

Signal transduction pathways regulating granulocyte differentiation and function
S Vereecken-Verploegen - library.uu.nl
... Integrin linked kinase (ILK) has been shown to phosphorylate PKB on Ser 473 in vitro
and when over expressed in cells 92 . ... 473 308 Active CaMKK ILK ? ? ? PRK2 ...
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Bortezomib as a potential treatment for prostate cancer - Full text - MIT Libraries
CN Papandreou, CJ Logothetis - Cancer Res, 2004 - cancerres.aacrjournals.org
... N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction ... S, Gray
V, et al Inhibition of integrin-linked kinase (ILK) suppresses activation of ...
Cited by 6 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Protein Phosphorylation and Signal Transduction Modulation: Chemistry Perspectives for Small- …
TK Sawyer, WC Shakespeare, Y Wang, R … - Medicinal Chemistry, 2005 - ingentaconnect.com
... Raf kinase Aurora kinases Protein Kinase-C (PKC) Protein Kinase-B (PKB/Akt) mTor
(FRAP) Polo-like kinases (Plk) Integrin-linked kinase (ILK) Glycogen synthase ...
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ON THE MECHANISMS OF INTERFERON ALPHA INDUCED APOPTOSIS
L THYRELL - diss.kib.ki.se
... Introduction of a constitutive active form of the STAT3 oncogene (STAT3C)
was shown to inhibit IFN's pro-apoptotic activity. The ...
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Clinical, cellular, and molecular aspects of cancer invasion - Full text - MIT Libraries
M Mareel, A Leroy, M Mareel, A Leroy - Physiol Rev, 2003 - intl-physrev.physiology.org
... is accompanied by localization of -CTN in the nucleus and an increased expression
of MMP-9, next to an increase of integrin-linked kinase (ILK), 1 - and 3 ...
Cited by 48 - Web Search - biochem.wisc.edu - ncbi.nlm.nih.gov - all 5 versions »

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological … - Full text - MIT Libraries
PP Roux, J Blenis - Microbiol. Mol. Biol. Rev, 2004 - pubmedcentral.nih.gov
... various membrane proteins (CD120a, Syk, and calnexin), nuclear substrates (SRC-1,
Pax6, NF-AT, Elk-1, MEF2, c-Fos, c-Myc, and STAT3), cytoskeletal proteins ...
Cited by 28 - Web Search - cellbio.med.harvard.edu - dx.doi.org - mmbr.asm.org - all 5 versions »

RNA interference: A primer for the uninitiated
RNAI Silencing - imgenex.com
Page 1. 2004 Catalog Update RNAi Products TLR Antibodies NF- B Antibodies & Inhibitors
Antibodies Expression Systems Kits & Reagents Recombinant Proteins ...
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A LIM protein, Hic-5, functions as a potential coactivator for Sp 1 - Full text - MIT Libraries
M Shibanuma, J Kim-Kaneyama, S Sato, K Nose - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... with multiple signaling molecules such as src, Crk, Csk, FAK, PYK2, ILK, PTP-PEST ...
Synergistic signaling in fetal brain by STAT3–Smad1 complex bridged by p300. ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Modulation of Vascular Endothelial Growth Factor Activity During Wound Healing Affects Granulation …
B Lange-Asschenfeldt, P Velasco, L Janes, L Brown, … - blackwell-synergy.com
... 004 Nuclear Translocation of Phosphorylated STAT3 is Essential for Endothelial Cell
Migration Induced by Basic FGF: STAT3 Phosphorylation is Involved in Tube ...
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SPECIALIZED LECTURES
J Bockaert, M Caron, T Schwartz, G Vassart, W … - blackwellpublishing.com
... Completely foreign chimeric receptors and, remarkably, in the absence of STAT3,
the endogenous IL-6 receptor can efficiently mediate an IFN-c-like response. ...
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Analysis of the Structure and Function of Protein Phosphatase 2A
K Schmidt - unibas.ch
Page 1. Analysis of the Structure and Function of Protein Phosphatase 2A
Inauguraldissertation zur Erlangung der Würde eines Doktors der Philosophie ...
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Bibliography Current World Literature
LSA Augustin, L DalMaso, CL Vecchia, M Parpinel, E … - Current Opinion in Oncology, 2002 - co-oncology.com
November 2002, 14:6 > Bibliography Current World Literature. ...
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